Search Results - "Pupier, Guilhem"
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Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer
Published in Immunity (Cambridge, Mass.) (08-03-2022)“…The presence of intratumoral tertiary lymphoid structures (TLS) is associated with positive clinical outcomes and responses to immunotherapy in cancer. Here,…”
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Unraveling the complex interplay between anti-tumor immune response and autoimmunity mediated by B cells and autoantibodies in the era of anti-checkpoint monoclonal antibody therapies
Published in Frontiers in immunology (2024)“…The intricate relationship between anti-tumor immunity and autoimmunity is a complex yet crucial aspect of cancer biology. Tumor microenvironment often…”
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B cells! Don't go the wrong way in this tumor
Published in Immunity (Cambridge, Mass.) (09-07-2024)“…The association of tertiary lymphoid structures (TLSs) with survival and immunotherapy response brought B cells to center stage. In a pan-cancer B cells atlas…”
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Tertiary lymphoid structures and B cells: An intratumoral immunity cycle
Published in Immunity (Cambridge, Mass.) (10-10-2023)“…The generation of anti-tumor immunity in the draining lymph nodes is known as the cancer immunity cycle. Accumulating evidence supports the occurrence of such…”
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Activation of B cells in Tertiary Lymphoid Structures in cancer: Anti-tumor or anti-self?
Published in Seminars in immunology (01-01-2023)“…Whereas T cells in the tumor microenvironment have been the main focus as cancer controlling cells and targets of immunotherapies, B cells have recently gained…”
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Abstract SY16-02: Generation of B cell immunity in tertiary lymphoid structures supports response to immunotherapy
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract The presence of tertiary lymphoid structures (TLSs) and a high intratumoral density of B lymphocytes have been associated with improved survival in…”
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