Search Results - "Puperi, Daniel S"

3-Dimensional spatially organized PEG-based hydrogels for an aortic valve co-culture model by Puperi, Daniel S, Balaoing, Liezl R, O'Connell, Ronan W, West, Jennifer L, Grande-Allen, K. Jane

“…Abstract Physiologically relevant in vitro models are needed to study disease progression and to develop and screen potential therapeutic interventions for…”
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Anisotropic poly(ethylene glycol)/polycaprolactone hydrogel-fiber composites for heart valve tissue engineering by Tseng, Hubert, Puperi, Daniel S, Kim, Eric J, Ayoub, Salma, Shah, Jay V, Cuchiara, Maude L, West, Jennifer L, Grande-Allen, K Jane

“…The recapitulation of the material properties and structure of the native aortic valve leaflet, specifically its anisotropy and laminate structure, is a major…”
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3D Printed Modeling of the Mitral Valve for Catheter-Based Structural Interventions by Vukicevic, Marija, Puperi, Daniel S., Jane Grande-Allen, K., Little, Stephen H.

“…As catheter-based structural heart interventions become increasingly complex, the ability to effectively model patient-specific valve geometry as well as the…”
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Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma by Chen, Yulong, Terajima, Masahiko, Yang, Yanan, Sun, Li, Ahn, Young-Ho, Pankova, Daniela, Puperi, Daniel S, Watanabe, Takeshi, Kim, Min P, Blackmon, Shanda H, Rodriguez, Jaime, Liu, Hui, Behrens, Carmen, Wistuba, Ignacio I, Minelli, Rosalba, Scott, Kenneth L, Sanchez-Adams, Johannah, Guilak, Farshid, Pati, Debananda, Thilaganathan, Nishan, Burns, Alan R, Creighton, Chad J, Martinez, Elisabeth D, Zal, Tomasz, Grande-Allen, K Jane, Yamauchi, Mitsuo, Kurie, Jonathan M

“…Epithelial tumor metastasis is preceded by an accumulation of collagen cross-links that heighten stromal stiffness and stimulate the invasive properties of…”
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Integrating valve-inspired design features into poly(ethylene glycol) hydrogel scaffolds for heart valve tissue engineering by Zhang, Xing, Xu, Bin, Puperi, Daniel S., Yonezawa, Aline L., Wu, Yan, Tseng, Hubert, Cuchiara, Maude L., West, Jennifer L., Grande-Allen, K. Jane

“…[Display omitted] The development of advanced scaffolds that recapitulate the anisotropic mechanical behavior and biological functions of the extracellular…”
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Ascorbic acid promotes extracellular matrix deposition while preserving valve interstitial cell quiescence within 3D hydrogel scaffolds by Wu, Yan, Puperi, Daniel S., Grande‐Allen, K. Jane, West, Jennifer L.

“…Current options for aortic valve replacements are non‐viable and thus lack the ability to grow and remodel, which can be problematic for paediatric…”
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Hyaluronan Hydrogels for a Biomimetic Spongiosa Layer of Tissue Engineered Heart Valve Scaffolds by Puperi, Daniel S, O’Connell, Ronan W, Punske, Zoe E, Wu, Yan, West, Jennifer L, Grande-Allen, K. Jane

“…Advanced tissue engineered heart valves must be constructed from multiple materials to better mimic the heterogeneity found in the native valve. The trilayered…”
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Electrospun Polyurethane and Hydrogel Composite Scaffolds as Biomechanical Mimics for Aortic Valve Tissue Engineering by Puperi, Daniel S, Kishan, Alysha, Punske, Zoe E, Wu, Yan, Cosgriff-Hernandez, Elizabeth, West, Jennifer L, Grande-Allen, K. Jane

“…In this study, a composite scaffold consisting of an electrospun polyurethane and poly­(ethylene glycol) hydrogel was investigated for aortic valve tissue…”
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Erratum to: 3D Printed Modeling of the Mitral Valve for Catheter-Based Structural Interventions by Vukicevic, Marija, Puperi, Daniel S., Grande-Allen, K. Jane, Little, Stephen H.

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Differential cell-matrix responses in hypoxia-stimulated aortic versus mitral valves by Sapp, Matthew C., Krishnamurthy, Varun K., Puperi, Daniel S., Bhatnagar, Saheba, Fatora, Gabrielle, Mutyala, Neelesh, Grande-Allen, K. Jane

“…Tissue oxygenation often plays a significant role in disease and is an essential design consideration for tissue engineering. Here, oxygen diffusion profiles…”
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Application of hydrogels in heart valve tissue engineering by Zhang, Xing, Xu, Bin, Puperi, Daniel S, Wu, Yan, West, Jennifer L, Grande-Allen, K Jane

“…With an increasing number of patients requiring valve replacements, there is heightened interest in advancing heart valve tissue engineering (HVTE) to provide…”
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Ascorbic acid promotes extracellular matrix deposition while preserving valve interstitial cell quiescence within 3D hydrogel scaffolds: Ascorbic acid and valve interstitial cells by Wu, Yan, Puperi, Daniel S., Grande-Allen, K. Jane, West, Jennifer L.

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Biomimetic heterogeneous scaffolds for a layered tissue engineered heart valve by Puperi, Daniel S

“…This dissertation describes strategies that I have developed to introduce mechanical and biochemical heterogeneity into synthetic tissue engineering scaffolds…”
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