Search Results - "Puolakkainen, P."

Classification, Severity Assessment, and Prevention of Recurrences in Acute Pancreatitis by Seppänen, H., Puolakkainen, P.

“…Background: Acute pancreatitis is a common disease, the incidence of which is 75–100/100,000/year in Finland. The worldwide incidence of acute pancreatitis is…”
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Activated matrix metalloproteinase 8 in serum predicts severity of acute pancreatitis by Turunen, A., Kuuliala, K., Kuuliala, A., Tervahartiala, T., Mustonen, H., Puolakkainen, P., Kylänpää, L., Sorsa, T.

“…Severe acute pancreatitis (SAP) has high morbidity and mortality but there are no widely accepted predictive biomarkers in clinical use. Matrix…”
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Long-term nationwide trends in the treatment of and outcomes among pancreatic cancer patients in Finland by Aaltonen, P., Carpén, O., Mustonen, H., Puolakkainen, P., Haglund, C., Peltola, K., Seppänen, H.

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Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: a multicentre study by Neoptolemos, JP, Kemppainen, EA, Mayer, JM, Fitzpatrick, JM, Raraty, MGT, Slavin, J, Beger, H-G, Hietaranta, AJ, Puolakkainen, PA

“…There is a pressing clinical requirement for an early simple test of severity in acute pancreatitis. We investigated the use of an assay of trypsinogen…”
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Signalling Profiles of Blood Leucocytes in Sepsis and in Acute Pancreatitis in Relation to Disease Severity by Kuuliala, K., Penttilä, A. K., Kaukonen, K.‐M., Mustonen, H., Kuuliala, A., Oiva, J., Hämäläinen, M., Moilanen, E., Pettilä, V., Puolakkainen, P., Kylänpää, L., Repo, H.

“…Intracellular signalling in blood leucocytes shows multiple aberrations in acute pancreatitis (AP) complicated by organ dysfunction (OD). We studied whether…”
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Disintegrin and metalloproteinases (ADAMs) expression in gastroesophageal reflux disease and in esophageal adenocarcinoma by Kauttu, T., Mustonen, H., Vainionpää, S., Krogerus, L., Ilonen, I., Räsänen, J., Salo, J., Puolakkainen, P.

“…Background Clinically useful marker molecules for the progression of gastroesophageal reflux disease and Barrett’s esophagus (BE) to esophageal adenocarcinoma…”
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Early prediction of organ failure by combined markers in patients with acute pancreatitis by Mentula, P., Kylänpää, M.-L., Kemppainen, E., Jansson, S.-E., Sarna, S., Puolakkainen, P., Haapiainen, R., Repo, H.

“…Background: Several biological markers and clinical scoring systems have been used to predict the course of acute pancreatitis. Because organ failure is the…”
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Early antibiotic treatment in acute necrotising pancreatitis by Sainio, V, Kemppainen, E, Puolakkainen, P, Taavitsainen, M, Kivisaari, L, Valtonen, V, Haapiainen, R, Schröder, T, Kivilaakso, E

“…Despite improvements in surgical treatment and intensive care, mortality from severe acute pancreatitis remains high. We have carried out a randomised study of…”
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The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice by Tiala, Inkeri, Wakkinen, Janica, Suomela, Sari, Puolakkainen, Pauli, Tammi, Raija, Forsberg, Sofi, Rollman, Ola, Kainu, Kati, Rozell, Björn, Kere, Juha, Saarialho-Kere, Ulpu, Elomaa, Outi

“…The CCHCR1 gene (Coiled-Coil α-Helical Rod protein 1) within the major psoriasis susceptibility locus PSORS1 is a plausible candidate gene for the risk effect…”
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Procalcitonin strip test in the early detection of severe acute pancreatitis by Kylänpää-Bäck, M.-L., Takala, A., Kemppainen, E., Puolakkainen, P., Haapiainen, R., Repo, H.

“…Background: Early identification of patients who subsequently develop severe acute pancreatitis would enable the selection of patients who may benefit from…”
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The effect of Helicobacter pylori eradication on the natural course of atrophic gastritis with dysplasia by Kokkola, A., Sipponen, P., Rautelin, H., Härkönen, M., Kosunen, T. U., Haapiainen, R., Puolakkainen, P.

“…Background: There are few data on the natural course of Helicobacter pylori‐related atrophic gastritis. Aim: To investigate the effect of H. pylori eradication…”
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Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing by Salmela, M. T., Pender, S. L. F., Karjalainen-Lindsberg, M.-L., Puolakkainen, P., MacDonald, T. T., Saarialho-Kere, U.

“…Background: Matrix metalloproteinases (MMPs) play a crucial role in wound healing of the skin, airways, and cornea, but data on MMPs in normal intestinal wound…”
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1063 POSTER Vasohibin-1 and Vasohibin-2 Are Expressed in Both Gastric Cancer Cells and Tumour-associated Macrophages and Play Roles in Anti-Angiogenesis Not Only as Intrinsic Inhibitors by Shen, Z.L, Seppánen, H, Vainionpáá, S, Ye, Y.J, Wang, S, Mustonen, H, Puolakkainen, P

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The Risk of Gastric Carcinoma and Carcinoid Tumours in Patients with Pernicious Anaemia: A Prospective Follow-Up Study by KOKKOLA, A, SJÖBLOM, S.-M, HAAPIAINEN, R, SIPPONEN, P, PUOLAKKAINEN, P, JÄRVINEN, H

“…Background: This endoscopic follow-up study was undertaken to evaluate the risk of gastric cancer (GC) and carcinoids in patients with pernicious anaemia (PA)…”
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Distinct expression profiles of stromelysin-2 (MMP-10), collagenase-3 (MMP-13), macrophage metalloelastase (MMP-12), and tissue inhibitor of metalloproteinases-3 (TIMP-3) in intestinal ulcerations by Vaalamo, M, Karjalainen-Lindsberg, ML, Puolakkainen, P, Kere, J, Saarialho-Kere, U

“…Programmed expression of matrix metalloproteinases is involved in wound healing in various organs. We have previously demonstrated enhanced expression of…”
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Serum amyloid A is a better early predictor of severity than C-reactive protein in acute pancreatitis by Mayer, J. M., Raraty, M., Slavin, J., Kemppainen, E., Fitzpatrick, J., Hietaranta, A., Puolakkainen, P., Beger, H. G., Neoptolemos, J. P.

“…Background: Serum amyloid A (SAA) is an early and sensitive marker of the extent of tissue trauma and inflammation. The aim of this study was to compare the…”
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Differential expression of three matrix metalloproteinases, MMP-19, MMP-26, and MMP-28, in normal and inflamed intestine and colon cancer by BISTER, V.-O, SALMELA, M. T, KARJALAINEN-LINDSBERG, M.-L, URIA, J, LOHI, J, PUOLAKKAINEN, P, LOPEZ-OTIN, C, SAARIALHO-KERE, U

“…Several matrix metalloproteinases (MMPs) have been implicated in intestinal inflammation, mucosal wound healing, and cancer progression. The purpose of this…”
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Intron 1 retaining cyclooxygenase 1 splice variant is induced by osmotic stress in human intestinal epithelial cells by Nurmi, J.T., Puolakkainen, P.A., Rautonen, N.E.

“…The biological roles of intron 1 retaining cyclooxygenase (Cox) 1 splice variants Cox-3 and PCox-1a (Cox-1ir) are not known. In humans, Cox-3 transcription has…”
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Anti-inflammatory macrophage induced MMP9 and ADAM8 expression increases invasion rate of pancreatic cancer cells by Seppänen, H, Mustonen, H, Vainionpää, S, Shen, Z.H, Repo, H, Kemppainen, E, Puolakkainen, P

“…Conclusion: Anti-inflammatory macrophages increase pancreatic cancer cell migration rate in basement membrane matrix by inducing ADAM8 and MMP9 expression in…”
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Cytokines as predictors of organ failure in severe acute pancreatitis by Nieminen, A, Maksimow, M, Mentula, P, Kyhälä, L, Kylänpää, L, Puolakkainen, P, Kemppainen, E, Repo, H, Salmi, M

“…Background: Acute pancreatitis (AP) causes a complex inflammatory response that can lead to multiple organ failure and death…”
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