Search Results - "Punyawudho, Baralee"
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Dosage Optimization of Efavirenz Based on a Population Pharmacokinetic–Pharmacogenetic Model of HIV-infected Patients in Thailand
Published in Clinical therapeutics (01-07-2020)“…Efavirenz exhibits high interindividual variability in plasma concentrations, leading to unpredictable efficacy and toxicity. Polymorphism of CYP2B6 516G > T…”
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Optimized fosfomycin regimens for treating carbapenem‐resistant Acinetobacter baumannii in critically ill patients with varying degrees of renal function
Published in Clinical and translational science (01-10-2024)“…Fosfomycin has been used to treat carbapenem‐resistant Acinetobacter baumannii (CRAB) infections. However, there is insufficient information on dosage…”
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Is Early Monitoring Better? Impact of Early Vancomycin Exposure on Treatment Outcomes and Nephrotoxicity in Patients with Methicillin-Resistant Staphylococcus aureus Infections
Published in Antibiotics (Basel) (01-10-2020)“…Optimal early vancomycin target exposure remains controversial. To clarify the therapeutic exposure range, we investigated the association between vancomycin…”
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Population Pharmacokinetics and Dose Optimization Based on Renal Function of Rivaroxaban in Thai Patients with Non-Valvular Atrial Fibrillation
Published in Pharmaceutics (21-08-2022)“…Low-dose rivaroxaban has been used in Asian patients with direct oral anticoagulants (DOACs) eligible for atrial fibrillation (AF). However, there are few…”
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Therapeutic drug monitoring of antiretroviral drugs in HIV-infected patients
Published in Expert review of clinical pharmacology (01-12-2016)“…Therapeutic drug monitoring (TDM) may be beneficial when applied to antiretroviral (ARV). Even though TDM can be a valuable strategy in HIV management, its…”
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Comparative Pharmacokinetics and Tissue Distribution of Hexahydrocurcumin Following Intraperitoneal vs Oral Administration in Mice Using LC-MS/MS
Published in ACS omega (01-10-2024)“…A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated to determine hexahydrocurcumin (HHC) levels in mouse plasma,…”
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Impact of Albumin and Omeprazole on Steady-State Population Pharmacokinetics of Voriconazole and Development of a Voriconazole Dosing Optimization Model in Thai Patients with Hematologic Diseases
Published in Antibiotics (Basel) (01-09-2020)“…This study aimed to identify factors that significantly influence the pharmacokinetics of voriconazole in Thai adults with hematologic diseases, and to…”
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Population pharmacokinetics of nevirapine in Thai HIV-infected patients
Published in Antiviral therapy (01-01-2014)“…Nevirapine-based antiretroviral therapy is widely used as a first-line treatment for HIV-infected patients in resource-limited settings. Nevirapine plasma…”
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Population Pharmacokinetics of Carbamazepine in Elderly Patients
Published in Therapeutic drug monitoring (01-04-2012)“…Carbamazepine is a commonly used antiepileptic drug in elderly patients. This study analyzed prospective data collected as part of a randomized, double-blinded…”
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Population pharmacokinetics of mycophenolate mofetil in Thai lupus nephritis patients
Published in International journal of clinical pharmacology and therapeutics (01-04-2012)“…Mycophenolic acid (MPA) has become the first-line drug therapy for proliferative lupus nephritis, a common and serious complication of systemic lupus…”
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Characterization of the Time Course of Carbamazepine Deinduction by an Enzyme Turnover Model
Published in Clinical pharmacokinetics (01-01-2009)“…Background and objective: Carbamazepine is a potent inducer of drug metabolizing enzymes, which results in a number of clinically significant drug-drug…”
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Influence of ABCC2 and ABCC4 polymorphisms on tenofovir plasma concentrations in Thai HIV-infected patients
Published in Antimicrobial agents and chemotherapy (01-06-2015)“…Tenofovir (TFV) is eliminated by renal excretion, which is mediated through multidrug-resistant protein 2 (MRP2) and MRP4, encoded by ABCC2 and ABCC4,…”
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Influence of the UGT2B7 -161C>T polymorphism on the population pharmacokinetics of lamotrigine in Thai patients
Published in European journal of clinical pharmacology (01-06-2013)“…Background and objectives: A high inter-individual variability in the pharmacokinetics of lamotrigine has been observed. Lamotrigine is primarily metabolized…”
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Population pharmacokinetics and dose optimisation of ritonavir-boosted atazanavir in thai HIV-infected patients
Published in International journal of antimicrobial agents (01-03-2017)“…Highlights • Population mean clearance (CL/ F ) of ATV in Thai HIV-infected patients was lower than reported values in other ethnicities. • ATV CL/F was…”
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The population pharmacokinetics of dolutegravir co-administered with rifampicin in Thai people living with HIV: Assessment of alternative dosing regimens
Published in CPT: pharmacometrics and systems pharmacology (23-09-2024)“…Tuberculosis is the most common opportunistic infection in individuals with HIV, and rifampicin is crucial in the treatment of tuberculosis. Drug-drug…”
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Population Pharmacokinetics of Pediatric Lopinavir/Ritonavir Oral Pellets in Children Living with HIV in Africa
Published in Clinical pharmacology and therapeutics (01-05-2024)“…Antiretroviral therapy for children living with HIV (CLHIV) under 3 years of age commonly includes lopinavir/ritonavir (LPV/r). However, the original liquid…”
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Pharmacogenetics-based population pharmacokinetic analysis of tenofovir in Thai HIV-infected patients
Published in Pharmacogenomics (01-11-2017)“…To develop a population pharmacokinetic model and identify sources of variability, genetic and nongenetic factors, of tenofovir. The and polymorphisms were…”
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Pharmacogenetics-based population pharmacokinetic analysis for dose optimization of ritonavir-boosted atazanavir in Thai adult HIV-infected patients
Published in Expert review of clinical pharmacology (02-01-2022)“…This population pharmacokinetic-pharmacogenetic study aimed to investigate the optimal dose of RTV-boosted ATV (ATV/RTV) for Thai adult HIV-infected patients…”
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Influence of CYP3A5 and SLCO1B1 polymorphisms on atazanavir/r concentrations in Thai HIV-infected patients
Published in Pharmacogenomics (01-05-2019)“…To evaluate the influence of genetic polymorphisms on plasma trough concentrations of atazanavir (ATV) and ritonavir (RTV). The concentration-to-dose ratios…”
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