Search Results - "Puma, D."

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory by Fá, M., Puzzo, D., Piacentini, R., Staniszewski, A., Zhang, H., Baltrons, M. A., Li Puma, D. D., Chatterjee, I., Li, J., Saeed, F., Berman, H. L., Ripoli, C., Gulisano, W., Gonzalez, J., Tian, H., Costa, J. A., Lopez, P., Davidowitz, E., Yu, W. H., Haroutunian, V., Brown, L. M., Palmeri, A., Sigurdsson, E. M., Duff, K. E., Teich, A. F., Honig, L. S., Sierks, M., Moe, J. G., D’Adamio, L., Grassi, C., Kanaan, N. M., Fraser, P. E., Arancio, O.

“…Non-fibrillar soluble oligomeric forms of amyloid-β peptide (oAβ) and tau proteins are likely to play a major role in Alzheimer’s disease (AD). The prevailing…”
Get full text

Neuromodulatory Action of Picomolar Extracellular Aβ42 Oligomers on Presynaptic and Postsynaptic Mechanisms Underlying Synaptic Function and Memory by Gulisano, Walter, Melone, Marcello, Ripoli, Cristian, Tropea, Maria Rosaria, Li Puma, Domenica D, Giunta, Salvatore, Cocco, Sara, Marcotulli, Daniele, Origlia, Nicola, Palmeri, Agostino, Arancio, Ottavio, Conti, Fiorenzo, Grassi, Claudio, Puzzo, Daniela

“…Failure of anti-amyloid-β peptide (Aβ) therapies against Alzheimer's disease (AD), a neurodegenerative disorder characterized by high amounts of the peptide in…”
Get full text

LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent by Puzzo, Daniela, Piacentini, Roberto, Fá, Mauro, Gulisano, Walter, Li Puma, Domenica D, Staniszewski, Agnes, Zhang, Hong, Tropea, Maria Rosaria, Cocco, Sara, Palmeri, Agostino, Fraser, Paul, D'Adamio, Luciano, Grassi, Claudio, Arancio, Ottavio

“…The concurrent application of subtoxic doses of soluble oligomeric forms of human amyloid-beta (oAβ) and Tau (oTau) proteins impairs memory and its…”
Get full text

Protection of primary neurons and mouse brain from Alzheimer’s pathology by molecular tweezers by Attar, Aida, Ripoli, Cristian, Riccardi, Elisa, Maiti, Panchanan, Li Puma, Domenica D., Liu, Tingyu, Hayes, Jane, Jones, Mychica R., Lichti-Kaiser, Kristin, Yang, Fusheng, Gale, Greg D., Tseng, Chi-hong, Tan, Miao, Xie, Cui-Wei, Straudinger, Jeffrey L., Klärner, Frank-Gerrit, Schrader, Thomas, Frautschy, Sally A., Grassi, Claudio, Bitan, Gal

“…Alzheimer’s disease is a devastating cureless neurodegenerative disorder affecting >35 million people worldwide. The disease is caused by toxic oligomers and…”
Get full text

Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer’s disease-like pathology by Tropea, Maria Rosaria, Li Puma, Domenica D., Melone, Marcello, Gulisano, Walter, Arancio, Ottavio, Grassi, Claudio, Conti, Fiorenzo, Puzzo, Daniela

“…•α7nAChR deletion causes an impairment of hippocampal synaptic plasticity and memory in 12-month-old mice.•α7 KO mice present an age-dependent increase of…”
Get full text

HSV-1 infection induces phosphorylated tau propagation among neurons via extracellular vesicles by Protto, V, Miteva, M T, Iannuzzi, F, Marcocci, M E, Li Puma, D D, Piacentini, R, Belli, M, Sansone, L, Pietrantoni, A, Grassi, C, Palamara, A T, De Chiara, G

“…Extracellular vesicles (EV), key players in cell-to-cell communication, may contribute to disease propagation in several neurodegenerative diseases, including…”
Get full text

Kappa free light chains is a valid tool in the diagnostics of MS: A large multicenter study by Leurs, CE, Twaalfhoven, HAM, Lissenberg-Witte, BI, van Pesch, V, Dujmovic, I, Drulovic, J, Castellazzi, M, Bellini, T, Pugliatti, M, Kuhle, J, Villar, LM, Alvarez-Cermeño, JC, Alvarez-Lafuente, R, Hegen, H, Deisenhammer, F, Walchhofer, LM, Thouvenot, E, Comabella, M, Montalban, X, Vécsei, L, Rajda, C, Galimberti, D, Scarpini, E, Altintas, A, Rejdak, K, Frederiksen, JL, Pihl-Jensen, G, Jensen, PEH, Khalil, M, Voortman, MM, Fazekas, F, Saiz, A, La Puma, D, Vercammen, M, Vanopdenbosch, L, Uitdehaag, BMJ, Killestein, J, Bridel, C, Teunissen, C

“…Objective: To validate kappa free light chain (KFLC) and lambda free light chain (LFLC) indices as a diagnostic biomarker in multiple sclerosis (MS). Methods:…”
Get full text

HSV-1 and Alzheimer's disease: more than a hypothesis by Piacentini, Roberto, De Chiara, Giovanna, Li Puma, Domenica D, Ripoli, Cristian, Marcocci, Maria E, Garaci, Enrico, Palamara, Anna T, Grassi, Claudio

“…Among the multiple factors concurring to Alzheimer's disease (AD) pathogenesis, greater attention should be devoted to the role played by infectious agents…”
Get full text

Effects of different amyloid β-protein analogues on synaptic function by Ripoli, Cristian, Piacentini, Roberto, Riccardi, Elisa, Leone, Lucia, Li Puma, Domenica D, Bitan, Gal, Grassi, Claudio

“…Abstract Perisynaptic accumulations of amyloid β-protein (Aβ) play a critical role in the synaptic dysfunction underlying the cognitive impairment observed in…”
Get full text

Extremely low-frequency electromagnetic fields enhance the survival of newborn neurons in the mouse hippocampus by Podda, Maria V., Leone, Lucia, Barbati, Saviana A., Mastrodonato, Alessia, Li Puma, Domenica D., Piacentini, Roberto, Grassi, Claudio

“…In recent years, much effort has been devoted to identifying stimuli capable of enhancing adult neurogenesis, a process that generates new neurons throughout…”
Get full text

Active case-finding for TB among incarcerated women in Peru by Puma, D., Geadas, C., Calderon, R. I., Yuen, C. M., Jiménez, J., CÓrdova, M., Martínez, B., Peinado, J., Lecca, L., Tovar, M.

Get full text

Study of Viscoelastic Rubber Mounts on Vehicle Suspensions with In-Wheel Electric Motors by Puma-Araujo, Santiago D., Galluzzi, Renato, Sánchez-Sánchez, Xavier, Ramirez-Mendoza, Ricardo A.

“…Rubber bushings and mounts are vastly used in automotive applications as support and interface elements. In suspension systems, they are commonly employed to…”
Get full text

Influence of the Processing Parameters on the Microstructure and Mechanical Properties of 316L Stainless Steel Fabricated by Laser Powder Bed Fusion by Barrionuevo, Germán Omar, Ramos-Grez, Jorge Andrés, Sánchez-Sánchez, Xavier, Zapata-Hidalgo, Daniel, Mullo, José Luis, Puma-Araujo, Santiago D.

“…Complex thermo-kinetic interactions during metal additive manufacturing reduce the homogeneity of the microstructure of the produced samples. Understanding the…”
Get full text

Focus on biological identity of endothelial progenitors cells by Zaccone, V, Flore, R, Santoro, L, De Matteis, G, Giupponi, B, Li Puma, D D, Santoliquido, A

“…Circulating Endothelial Progenitor Cells (EPCs) were discovered by Asahara et al in 1997 and defined as bone marrow CD34+/KDR+ cells endowed with angiogenic…”
Get more information

Intracellular Accumulation of Amyloid-  (A ) Protein Plays a Major Role in A -Induced Alterations of Glutamatergic Synaptic Transmission and Plasticity by Ripoli, C., Cocco, S., Li Puma, D. D., Piacentini, R., Mastrodonato, A., Scala, F., Puzzo, D., D'Ascenzo, M., Grassi, C.

Get full text

Prevalence of red ear syndrome in juvenile primary headaches by Raieli, V, Compagno, A, Brighina, F, La Franca, G, Puma, D, Ragusa, D, Savettieri, G, D'Amelio, M

“…Previous studies have suggested a relationship between 'red ear syndrome' (RES) and pediatric migraine. Aims of this study were (i) to assess the frequency,…”
Get more information

The effect of amyloid-β peptide on synaptic plasticity and memory is influenced by different isoforms, concentrations, and aggregation status by Gulisano, Walter, Melone, Marcello, Li Puma, Domenica D., Tropea, Maria Rosaria, Palmeri, Agostino, Arancio, Ottavio, Grassi, Claudio, Conti, Fiorenzo, Puzzo, Daniela

“…The increase of oligomeric amyloid-beta (oAβ) has been related to synaptic dysfunction, thought to be the earliest event in Alzheimer's disease…”
Get full text

Intracellular accumulation of amyloid-β (Aβ) protein plays a major role in Aβ-induced alterations of glutamatergic synaptic transmission and plasticity by Ripoli, Cristian, Cocco, Sara, Li Puma, Domenica D, Piacentini, Roberto, Mastrodonato, Alessia, Scala, Federico, Puzzo, Daniela, D'Ascenzo, Marcello, Grassi, Claudio

“…Intracellular accumulation of amyloid-β (Aβ) protein has been proposed as an early event in AD pathogenesis. In patients with mild cognitive impairment,…”
Get full text

Tau is not necessary for amyloid-β-induced synaptic and memory impairments by Puzzo, Daniela, Argyrousi, Elentina K, Staniszewski, Agnieszka, Zhang, Hong, Calcagno, Elisa, Zuccarello, Elisa, Acquarone, Erica, Fa', Mauro, Li Puma, Domenica D, Grassi, Claudio, D'Adamio, Luciano, Kanaan, Nicholas M, Fraser, Paul E, Arancio, Ottavio

“…The amyloid hypothesis posits that the amyloid-beta (Aβ) protein precedes and requires microtubule-associated protein tau in a sort of trigger-bullet mechanism…”
Get full text

The prevalence of allodynia, osmophobia and red ear syndrome in the juvenile headache: preliminary data by Raieli, Vincenzo, Pandolfi, Eleonora, La Vecchia, Michela, Puma, Domenico, Calò, Alessandra, Celauro, Antonio, Ragusa, Donatella

“…The aim of the study was to determine the frequency of clinical allodynia, osmophobia and red ear syndrome in a young population. Medical records of the…”
Get full text