Search Results - "Puls, T. J."

3D collagen fibrillar microstructure guides pancreatic cancer cell phenotype and serves as a critical design parameter for phenotypic models of EMT by Puls, T J, Tan, Xiaohong, Whittington, Catherine F, Voytik-Harbin, Sherry L

“…Pancreatic cancer, one of the deadliest cancers, is characterized by high rates of metastasis and intense desmoplasia, both of which are associated with…”
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Development of a Novel 3D Tumor-tissue Invasion Model for High-throughput, High-content Phenotypic Drug Screening by Puls, T. J., Tan, Xiaohong, Husain, Mahera, Whittington, Catherine F., Fishel, Melissa L., Voytik-Harbin, Sherry L.

“…While much progress has been made in the war on cancer, highly invasive cancers such as pancreatic cancer remain difficult to treat and anti-cancer clinical…”
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Thrombin generation and fibrin formation under flow on biomimetic tissue factor‐rich surfaces by Onasoga‐Jarvis, A. A., Puls, T. J., O'Brien, S. K., Kuang, L., Liang, H. J., Neeves, K. B.

“…Summary Background Blood flow regulates coagulation and fibrin assembly by controlling the rate of transport of zymogens, enzymes and plasma proteins to and…”
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Abstract A57: Novel 3D tumor-stromal model highlights the importance of ECM composition and biophysical properties in pancreatic cancer EMT and drug resistance by Puls, TJ, Tan, Xiaohong, Whittington, Catherine, Voytik-Harbin, Sherry

“…Abstract Introduction: Epithelial to mesenchymal transition (EMT), where cells detach from basement membrane (BM) and invade interstitial matrix (IM), plays a…”
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Abstract 5783: In vitro modeling of patient derived bladder cancer cell lines in 3D culture systems by Elbanna, May, Chintala, Sreenivasulu, Ciamporcero, Eric, Adelayie, Remi, Orillion, Ashley, Arisa, Sreevani, Damayanti, Nur, Grimard, Michelle, Puls, TJ, Harbin, Sherry, Fishel, Melissa, Pili, Roberto

“…Abstract Background: Drug screening is a key component for drug development and optimizing anti-tumor therapies. Traditionally, in vitro drug testing has been…”
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