Search Results - "Pullinger, R"

A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci by Liu, Ying, Helms, Cynthia, Liao, Wilson, Zaba, Lisa C, Duan, Shenghui, Gardner, Jennifer, Wise, Carol, Miner, Andrew, Malloy, M J, Pullinger, Clive R, Kane, John P, Saccone, Scott, Worthington, Jane, Bruce, Ian, Kwok, Pui-Yan, Menter, Alan, Krueger, James, Barton, Anne, Saccone, Nancy L, Bowcock, Anne M

“…A genome-wide association study was performed to identify genetic factors involved in susceptibility to psoriasis (PS) and psoriatic arthritis (PSA),…”
Get full text

Rare and Common Variants in CARD14, Encoding an Epidermal Regulator of NF-kappaB, in Psoriasis by Jordan, Catherine T., Cao, Li, Roberson, Elisha D.O., Duan, Shenghui, Helms, Cynthia A., Nair, Rajan P., Duffin, Kristina Callis, Stuart, Philip E., Goldgar, David, Hayashi, Genki, Olfson, Emily H., Feng, Bing-Jian, Pullinger, Clive R., Kane, John P., Wise, Carol A., Goldbach-Mansky, Raphaela, Lowes, Michelle A., Peddle, Lynette, Chandran, Vinod, Liao, Wilson, Rahman, Proton, Krueger, Gerald G., Gladman, Dafna, Elder, James T., Menter, Alan, Bowcock, Anne M.

“…Psoriasis is a common inflammatory disorder of the skin and other organs. We have determined that mutations in CARD14, encoding a nuclear factor of kappa light…”
Get full text

KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients by Terrelonge, Mark, LaHue, Sara C., Tang, Christopher, Movsesyan, Irina, Pullinger, Clive R., Dubal, Dena B., Leung, Jacqueline, Douglas, Vanja C.

“…Despite the association between cognitive impairment and delirium, little is known about whether genetic differences that confer cognitive resilience also…”
Get full text

Separation of postprandial lipoproteins: improved purification of chylomicrons using an ApoB100 immunoaffinity method by Jones, Grace Marie, Caccavello, Russell, Palii, Sergiu P., Pullinger, Clive R., Kane, John P., Mulligan, Kathleen, Gugliucci, Alejandro, Schwarz, Jean-Marc

“…Elevated levels of triglyceride-rich lipoproteins (TRLs), both fasting and postprandial, are associated with increased risk for atherosclerosis. However,…”
Get full text

APOL1 Risk Variants Associate With the Prevalence of Stroke in African American Current and Past Smokers by Rakic, Jelena Mustra, Pullinger, Clive R, Van Blarigan, Erin L, Movsesyan, Irina, Stock, Eveline Oestreicher, Malloy, Mary J, Kane, John P

“…African American smokers have 2.5 times higher risk for stroke compared with nonsmokers (higher than other races). About 50% of the African American population…”
Get full text

Partial LPL deletions: rare copy-number variants contributing towards severe hypertriglyceridemia by Dron, Jacqueline S., Wang, Jian, McIntyre, Adam D., Cao, Henian, Robinson, John F., Duell, P. Barton, Manjoo, Priya, Feng, James, Movsesyan, Irina, Malloy, Mary J., Pullinger, Clive R., Kane, John P., Hegele, Robert A.

“…Severe hypertriglyceridemia (HTG) is a relatively common form of dyslipidemia with a complex pathophysiology and serious health complications. HTG can develop…”
Get full text

Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia by Dong, Weilai, Wong, Karen H.Y., Liu, Youbin, Levy-Sakin, Michal, Hung, Wei-Chien, Li, Mo, Li, Boyang, Jin, Sheng Chih, Choi, Jungmin, Lopez-Giraldez, Francesc, Vaka, Dedeepya, Poon, Annie, Chu, Catherine, Lao, Richard, Balamir, Melek, Movsesyan, Irina, Malloy, Mary J., Zhao, Hongyu, Kwok, Pui-Yan, Kane, John P., Lifton, Richard P., Pullinger, Clive R.

“…Low levels of high density lipoprotein-cholesterol (HDL-C) are associated with an elevated risk of arteriosclerotic coronary heart disease. Heritability of…”
Get full text

Association of functionally significant Melanocortin-4 but not Melanocortin-3 receptor mutations with severe adult obesity in a large North American case–control study by Calton, Melissa A., Ersoy, Baran A., Zhang, Sumei, Kane, John P., Malloy, Mary J., Pullinger, Clive R., Bromberg, Yana, Pennacchio, Len A., Dent, Robert, McPherson, Ruth, Ahituv, Nadav, Vaisse, Christian

“…Functionally significant heterozygous mutations in the Melanocortin-4 receptor (MC4R) have been implicated in 2.5% of early onset obesity cases in European…”
Get full text

Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function by Mak, Angel C Y, Pullinger, Clive R, Tang, Ling Fung, Wong, Jinny S, Deo, Rahul C, Schwarz, Jean-Marc, Gugliucci, Alejandro, Movsesyan, Irina, Ishida, Brian Y, Chu, Catherine, Poon, Annie, Kim, Phillip, Stock, Eveline O, Schaefer, Ernst J, Asztalos, Bela F, Castellano, Joseph M, Wyss-Coray, Tony, Duncan, Jacque L, Miller, Bruce L, Kane, John P, Kwok, Pui-Yan, Malloy, Mary J

“…The identification of a patient with a rare form of severe dysbetalipoproteinemia allowed the study of the consequences of total absence of apolipoprotein E…”
Get more information

An internal promoter underlies the difference in disease severity between N- and C-terminal truncation mutations of Titin in zebrafish by Zou, Jun, Tran, Diana, Baalbaki, Mai, Tang, Ling Fung, Poon, Annie, Pelonero, Angelo, Titus, Erron W, Yuan, Christiana, Shi, Chenxu, Patchava, Shruthi, Halper, Elizabeth, Garg, Jasmine, Movsesyan, Irina, Yin, Chaoying, Wu, Roland, Wilsbacher, Lisa D, Liu, Jiandong, Hager, Ronald L, Coughlin, Shaun R, Jinek, Martin, Pullinger, Clive R, Kane, John P, Hart, Daniel O, Kwok, Pui-Yan, Deo, Rahul C

“…Truncating mutations in the giant sarcomeric protein Titin result in dilated cardiomyopathy and skeletal myopathy. The most severely affected dilated…”
Get full text

Apolipoprotein E e4 allele increases the risk of early postoperative delirium in older patients undergoing noncardiac surgery by Leung, Jacqueline M, Sands, Laura P, Wang, Yun, Poon, Annie, Kwok, Pui-yan, Kane, John P, Pullinger, Clive R

“…Whether patients who subsequently develop early postoperative delirium have a genetic predisposition that renders them at risk for postoperative delirium has…”
Get full text

Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia by Reue, Karen, Péterfy, Miklós, Malloy, Mary J, Pajukanta, Päivi, Mao, Hui Z, Weissglas-Volkov, Daphna, Pullinger, Clive R, Frost, Philip H, Doolittle, Mark H, Ben-Zeev, Osnat, Aouizerat, Bradley E, Kane, John P

“…Hypertriglyceridemia is a hallmark of many disorders, including metabolic syndrome, diabetes, atherosclerosis and obesity. A well-known cause is the deficiency…”
Get full text

The acute wheezy adult with airways disease in the emergency department: a retrospective case-note review of exacerbations of COPD by Russell, Rek, Beer, S, Pavord, I D, Pullinger, R, Bafadhel, M

“…There has been an increase in interest in the peripheral blood eosinophil count as a biomarker in COPD. Few studies have examined the eosinophil count in…”
Get full text

Levels of Prebeta-1 High-Density Lipoprotein Are a Strong Independent Positive Risk Factor for Coronary Heart Disease and Myocardial Infarction: A Meta-Analysis by Pullinger, Clive R, O'Connor, Patricia M, Naya-Vigne, Josefina M, Kunitake, Steven T, Movsesyan, Irina, Frost, Philip H, Malloy, Mary J, Kane, John P

“…Background We previously showed that levels of prebeta-1 high-density lipoprotein (HDL), the principal acceptor of cholesterol effluxed from cells, including…”
Get full text

Relation of Increased Prebeta-1 High-Density Lipoprotein Levels to Risk of Coronary Heart Disease by Guey, Lin T., PhD, Pullinger, Clive R., PhD, Ishida, Brian Y., PhD, O'Connor, Patricia M., MD, Zellner, Christian, MD, Francone, Omar L., PhD, Laramie, Jason M., PhD, Naya-Vigne, Josefina M., MD, Siradze, Ketevan A., MD, Deedwania, Prakash, MD, Redberg, Rita F., MD, Frost, Philip H., MD, Seymour, Albert B., PhD, Kane, John P., MD, PhD, Malloy, Mary J., MD

“…Preβ-1 high-density lipoprotein (HDL) plays a key role in reverse cholesterol transport by promoting cholesterol efflux. Our aims were (1) to test previous…”
Get full text

Symptom Experience in HIV-Infected Adults: A Function of Demographic and Clinical Characteristics by Lee, Kathryn A., RN, PhD, Gay, Caryl, PhD, Portillo, Carmen J., RN, PhD, Coggins, Traci, BS, Davis, Harvey, RN, PhD, Pullinger, Clive R., PhD, Aouizerat, Bradley E., PhD

“…Abstract Personal characteristics that interact with both HIV diagnosis and its medical management can influence symptom experience. Little is known about how…”
Get full text

Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia by Beigneux, Anne P, Miyashita, Kazuya, Ploug, Michael, Blom, Dirk J, Ai, Masumi, Linton, MacRae F, Khovidhunkit, Weerapan, Dufour, Robert, Garg, Abhimanyu, McMahon, Maureen A, Pullinger, Clive R, Sandoval, Norma P, Hu, Xuchen, Allan, Christopher M, Larsson, Mikael, Machida, Tetsuo, Murakami, Masami, Reue, Karen, Tontonoz, Peter, Goldberg, Ira J, Moulin, Philippe, Charrière, Sybil, Fong, Loren G, Nakajima, Katsuyuki, Young, Stephen G

“…Six patients with severe hypertriglyceridemia (chylomicronemia) were found to have autoantibodies against a capillary endothelial-cell protein (GPIHBP1) that…”
Get full text

Assessing the Role of the Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1) Three-finger Domain in Binding Lipoprotein Lipase by Beigneux, Anne P., Davies, Brandon S.J., Tat, Shelly, Chen, Jenny, Gin, Peter, Voss, Constance V., Weinstein, Michael M., Bensadoun, André, Pullinger, Clive R., Fong, Loren G., Young, Stephen G.

“…Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) is an endothelial cell protein that transports lipoprotein lipase…”
Get full text

Cytokine Polymorphisms are Associated with Daytime Napping in Adults Living with HIV by Byun, Eeeseung, RN, PhD, Gay, Caryl L., PhD, Portillo, Carmen J., RN, PhD, Pullinger, Clive R., PhD, Aouizerat, Bradley E., MAS, PhD, Lee, Kathryn A., RN, PhD

“…Abstract Objective/Background Daytime napping longer than one hour has been associated with an increased risk for all-cause mortality. Associations between…”
Get full text

Identification of Four Gene Variants Associated with Myocardial Infarction by Shiffman, Dov, Ellis, Stephen G., Rowland, Charles M., Malloy, Mary J., Luke, May M., Iakoubova, Olga A., Pullinger, Clive R., Cassano, June, Aouizerat, Bradley E., Fenwick, Raymond G., Reitz, Richard E., Catanese, Joseph J., Leong, Diane U., Zellner, Christian, Sninsky, John J., Topol, Eric J., Devlin, James J., Kane, John P.

“…Family history is a major risk factor for myocardial infarction (MI). However, known gene variants associated with MI cannot fully explain the genetic…”
Get full text