Search Results - "Pulivendala, Gauthami"

Honokiol: A polyphenol neolignan ameliorates pulmonary fibrosis by inhibiting TGF-β/Smad signaling, matrix proteins and IL-6/CD44/STAT3 axis both in vitro and in vivo by Pulivendala, Gauthami, Bale, Swarna, Godugu, Chandraiah

“…Pulmonary fibrosis (PF) is an epithelial/fibroblastic crosstalk disorder of the lungs with highly complex etiopathogenesis. Limited treatment possibilities are…”
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Niclosamide alleviates pulmonary fibrosis in vitro and in vivo by attenuation of epithelial-to-mesenchymal transition, matrix proteins & Wnt/β-catenin signaling: A drug repurposing study by Boyapally, Raju, Pulivendala, Gauthami, Bale, Swarna, Godugu, Chandraiah

“…Drug repurposing off late has been emerging as an inspiring alternative approach to conventional, exhaustive and arduous process of drug discovery. It is a…”
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Inhalation of sustained release microparticles for the targeted treatment of respiratory diseases by Pulivendala, Gauthami, Bale, Swarna, Godugu, Chandraiah

“…Delivering drugs through inhalation for systemic and local applications has been in practice since several decades to treat various diseases. In recent times,…”
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Ferulic acid ameliorates the progression of pulmonary fibrosis via inhibition of TGF-β/smad signalling by Ali, Syed Afroz, Saifi, Mohd Aslam, Pulivendala, Gauthami, Godugu, Chandraiah, Talla, Venu

“…Natural products are one of the best sources for the discovery of novel drugs and compounds for multiple diseases. Pulmonary fibrosis (PF) is a chronic,…”
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Withaferin A attenuates bleomycin‐induced scleroderma by targeting FoxO3a and NF‐κβ signaling: Connecting fibrosis and inflammation by Bale, Swarna, Pulivendala, Gauthami, Godugu, Chandraiah

“…Scleroderma is an inflammatory autoimmune disease which begins with inflammation due to tissue injury and advances to progressive accumulation of extracellular…”
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Nimbolide ameliorates fibrosis and inflammation in experimental murine model of bleomycin-induced scleroderma by Diddi, Snehalatha, Bale, Swarna, Pulivendala, Gauthami, Godugu, Chandraiah

“…Background Clinical manifestations of skin fibrosis are very variable and ambiguous, making its management quite critical and challenging. The lack of…”
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Synthesis and evaluation of new 4(3H)-Quinazolinone derivatives as potential anticancer agents by Gatadi, Srikanth, Pulivendala, Gauthami, Gour, Jitendra, Malasala, Satyaveni, Bujji, Sushmitha, Parupalli, Ramulu, Shaikh, Mujahid, Godugu, Chandraiah, Nanduri, Srinivas

“…A series of new 4(3H)-quinazolinones were synthesized and evaluated for their cytotoxic activity against a set of human cancer cell lines MDA-MB-231 and MCF-7…”
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Therapeutic effects of Nimbolide, an autophagy regulator, in ameliorating pulmonary fibrosis through attenuation of TGF-β1 driven epithelial-to-mesenchymal transition by Prashanth Goud, M., Bale, Swarna, Pulivendala, Gauthami, Godugu, Chandraiah

“…Pulmonary fibrosis is an irreversible lung disorder with predictable decline in lung function leading to respiratory insufficiency. Incidence of pulmonary…”
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Abstract 7064: BRCA 1/2 haploinsufficiency-associated metabolic dysfunction in benign fallopian tube epithelia by Ravix, Jovanka, Paudel, Iru, Pulivendala, Gauthami, Sowamber, Ramlogan, Smith, Elizabeth, Schlumbrecht, Matthew, Lombard, David, George, Sophia

“…In 3-17% of women with BRCA1/2 mutations who undergo risk-reducing surgery, pre-neoplastic and neoplastic lesions are found in their fallopian tubes that…”
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Natural product topical therapy in mitigating imiquimod-induced psoriasis-like skin inflammation-underscoring the anti-psoriatic potential of Nimbolide by More, Nilesh, Sharma, Nivya, Pulivendala, Gauthami, Bale, Swarna, Godugu, Chandraiah

“…BACKGROUND: Psoriasis is a chronic inflammatory dermatological disorder having complex pathophysiology with autoimmune and genetic factors being the major…”
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Abstract C038: BRCA2 haploinsufficiency driven neoplastic events in the fallopian tube epithelia by Ravix, Jovanka, Paudel, Iru, Sowamber, Ramlogan, Pulivendala, Gauthami, Lombard, David, George, Sophia

“…One in 70 women will develop ovarian cancer over their lifetime in the US and epithelial ovarian cancer (EOC) remains the deadliest gynecological cancer. EOC…”
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