Search Results - "Puligilla, Ramya"

Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney by Bolten, Jan Stephan, Tanner, Christine, Rodgers, Griffin, Schulz, Georg, Levano, Soledad, Weitkamp, Timm, Waldner, Samuel, Puligilla, Ramya Deepthi, Bodmer, Daniel, Müller, Bert, Huwyler, Jörg

“…Nephrotoxicity is an important drug safety aspect to be assessed during drug discovery and development. To study renal toxicity, in vitro cell-based assays are…”
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High efficiency preparation of monodisperse plasma membrane derived extracellular vesicles for therapeutic applications by Alter, Claudio L., Detampel, Pascal, Schefer, Roman B., Lotter, Claudia, Hauswirth, Patrick, Puligilla, Ramya D., Weibel, Vera J., Schenk, Susanne H., Heusermann, Wolf, Schürz, Melanie, Meisner-Kober, Nicole, Palivan, Cornelia, Einfalt, Tomaž, Huwyler, Jörg

“…Extracellular vesicles (EVs) are highly interesting for the design of next-generation therapeutics. However, their preparation methods face challenges in…”
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Zebrafish Larvae as an in vivo Model for Antimicrobial Activity Tests against Intracellular Salmonella by Hauswirth, Patrick, Buck, Jonas, Puligilla, Ramya, Alter, Claudio Luca, Sieber, Sandro, Claudi, Beatrice, Fanous, Joseph, Bumann, Dirk, Huwyler, Jörg

“…Blood infections from multi-drug-resistant pose a major health burden. This is especially true because can survive and replicate intracellularly, and the…”
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Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments by Hopf, Nancy B, Suter-Dick, Laura, Huwyler, Jörg, Borgatta, Myriam, Hegg, Lucie, Pamies, David, Paschoud, Hélène, Puligilla, Ramya Deepthi, Reale, Elena, Werner, Sophie, Zurich, Marie-Gabrielle

“…Chemicals are not required to be tested systematically for their neurotoxic potency, although they may contribute to the development of several neurological…”
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Comparison of ionizable lipids for lipid nanoparticle mediated DNA delivery by Lotter, Claudia, Kuzucu, Evrim Ümit, Casper, Jens, Alter, Claudio Luca, Puligilla, Ramya Deepthi, Detampel, Pascal, Lopez, Juana Serrano, Ham, Alexander Sebastian, Huwyler, Jörg

“…•DNA delivery via lipid nanoparticle (LNP) formulations is underexplored.•Our study combines DNA expression plasmids with clinically used ionizable lipids.•In…”
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Zebrafish by Bolten, Jan Stephan, Tanner, Christine, Rodgers, Griffin, Schulz, Georg, Levano, Soledad, Weitkamp, Timm, Waldner, Samuel, Puligilla, Ramya Deepthi, Bodmer, Daniel, Müller, Bert, Huwyler, Jörg

“…Nephrotoxicity is an important drug safety aspect to be assessed during drug discovery and development. To study renal toxicity, in vitro cell-based assays are…”
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Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models by Bolten, Jan Stephan, Mancuso, Riccardo Vincenzo, Roos, Noëmi Johanna, Mayr, Aline, Puligilla, Ramya Deepthi, Kraus, Lisa, Odermatt, Alex, Fricker, Gert, Huwyler, Jörg

“…Iopamidol is a nonionic, low-osmolar iodinated contrast agent used for angiography. Its clinical use is associated with renal dysfunction. Patients suffering…”
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Nano Plasma Membrane Vesicle‐Lipid Nanoparticle Hybrids for Enhanced Gene Delivery and Expression by Alter, Claudio Luca, Lotter, Claudia, Puligilla, Ramya Deepthi, Bolten, Jan Stephan, Sedzicki, Jaroslaw, Marchese, Jason, Schittny, Valentin, Rucci, Francesca, Beverly, Michael, Palivan, Cornelia G., Detampel, Pascal, Einfalt, Tomaž, Huwyler, Jörg

“…Abstract Lipid nanoparticles (LNPs) have emerged as the leading nonviral nucleic acid (NA) delivery system, gaining widespread attention for their use in…”
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Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney by Jan Stephan Bolten, Christine Tanner, Griffin Rodgers, Georg Schulz, Soledad Levano, Timm Weitkamp, Samuel Waldner, Ramya Deepthi Puligilla, Daniel Bodmer, Bert Müller, Jörg Huwyler

“…Nephrotoxicity is an important drug safety aspect to be assessed during drug discovery and development. To study renal toxicity, in vitro cell-based assays are…”
Get full text