Search Results - "Pulido, Marina"

Characterization of Extended-Spectrum β-Lactamase-Producing Shigella sonnei in Spain: Expanding the Geographic Distribution of Sequence Type 152/CTX-M-27 Clone by López-Cerero, Lorena, Stolz, Emilio, Pulido, Marina R, Pascual, Alvaro

“…We describe the first occurrence in Spain of community cases of CTX-M-27-producing Shigella sonnei sequence type 152 (ST152), resistant to quinolones and…”
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Immunization with lipopolysaccharide-deficient whole cells provides protective immunity in an experimental mouse model of Acinetobacter baumannii infection by García-Quintanilla, Meritxell, Pulido, Marina R, Pachón, Jerónimo, McConnell, Michael J

“…The increasing clinical importance of infections caused by multidrug resistant Acinetobacter baumannii warrants the development of novel approaches for…”
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A lipopolysaccharide-free outer membrane vesicle vaccine protects against Acinetobacter baumannii infection by Pulido, Marina R., García-Quintanilla, Meritxell, Pachón, Jerónimo, McConnell, Michael J.

“…•LPS-deficient A. baumannii produces outer membrane vesicles (OMVs).•OMVs derived from LPS-free A. baumannii are highly immunogenic.•Immunization with OMVs…”
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Identification of a Stable Chromosomal Tandem Multicopy of bla VIM-63 , a New bla VIM-2 Carbapenemase by Pulido, Marina R, García-Montaner, Andrea, López-Cerero, Lorena, Fernández-Cuenca, Felipe, Gutiérrez-Fernández, José, Pascual, Álvaro

“…This study characterizes a new genetic structure containing a multicopy of a variant with an A676C substitution, . This gene was detected on the chromosome of…”
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Identification of a Stable Chromosomal Tandem Multicopy of blaVIM-63, a New blaVIM-2 Carbapenemase by Pulido, Marina R., García-Montaner, Andrea, López-Cerero, Lorena, Fernández-Cuenca, Felipe, Gutiérrez-Fernández, José, Pascual, Álvaro

“…This study characterizes a new genetic structure containing a multicopy of a blaVIM-2 variant with an A676C substitution, blaVIM-63. This gene was detected on…”
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Genetic features of BEL-1-producing and KPC-2-producing E. coli from hospital wastewater: human source or sewages adaptation by Romero-Oraá, Laura, Pulido, Marina R., Galán, Fatima, Palacios, María Victoria García, Pascual, Alvaro, López-Cerero, Lorena

“…Hospital sewage is an ecosystem that facilitates the transfer of antibiotic and heavy metal resistance genes and the interaction of human and environmental…”
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Rab18 dynamics in adipocytes in relation to lipogenesis, lipolysis and obesity by Pulido, Marina R, Diaz-Ruiz, Alberto, Jiménez-Gómez, Yolanda, Garcia-Navarro, Socorro, Gracia-Navarro, Francisco, Tinahones, Francisco, López-Miranda, José, Frühbeck, Gema, Vázquez-Martínez, Rafael, Malagón, Maria M

“…Lipid droplets (LDs) are organelles that coordinate lipid storage and mobilization, both processes being especially important in cells specialized in managing…”
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Emerging therapies for multidrug resistant Acinetobacter baumannii by García-Quintanilla, Meritxell, Pulido, Marina R, López-Rojas, Rafael, Pachón, Jerónimo, McConnell, Michael J

“…The global emergence of multidrug resistant Acinetobacter baumannii has reduced the number of clinically available antibiotics that retain activity against…”
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Pazopanib or methotrexate–vinblastine combination chemotherapy in adult patients with progressive desmoid tumours (DESMOPAZ): a non-comparative, randomised, open-label, multicentre, phase 2 study by Toulmonde, Maud, MD, Pulido, Marina, MSc, Ray-Coquard, Isabelle, Prof, Andre, Thierry, Prof, Isambert, Nicolas, MD, Chevreau, Christine, MD, Penel, Nicolas, Prof, Bompas, Emmanuelle, MD, Saada, Esma, MD, Bertucci, François, MD, Lebbe, Celeste, MD, Le Cesne, Axel, MD, Soulie, Patrick, MD, Piperno-Neumann, Sophie, MD, Sweet, Stephen, PhD, Cecchi, Fabiola, PhD, Hembrough, Todd, PhD, Bellera, Carine, PhD, Kind, Michèle, MD, Crombe, Amandine, MD, Lucchesi, Carlo, PhD, Le Loarer, François, MD, Blay, Jean-Yves, Prof, Italiano, Antoine, Prof

“…SummaryBackgroundDesmoid tumours are locally aggressive tumours associated with substantial morbidity. No systemic treatments are approved for this disease,…”
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First steps towards a vaccine against Acinetobacter baumannii by Garcia-Quintanilla, Meritxell, Pulido, Marina R, McConnell, Michael J

“…Acinetobacter baumannii has become an important cause of human infections, most notably in the hospital setting. In addition, the global dissemination of…”
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Progress on the development of rapid methods for antimicrobial susceptibility testing by Pulido, Marina R, García-Quintanilla, Meritxell, Martín-Peña, Reyes, Cisneros, José Miguel, McConnell, Michael J

“…Antimicrobial susceptibility testing is essential for guiding the treatment of many types of bacterial infections, especially in the current context of rising…”
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Immunization with lipopolysaccharide-free outer membrane complexes protects against Acinetobacter baumannii infection by Pulido, Marina R., García-Quintanilla, Meritxell, Pachón, Jerónimo, McConnell, Michael J.

“…•OMCs extracted from LPS-free A. baumannii are highly immunogenic.•Immunization with OMCs from LPS-free A. baumannii provides protective immunity.•The presence…”
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Pathogenic Acinetobacter species have a functional type I secretion system and contact-dependent inhibition systems by Harding, Christian M., Pulido, Marina R., Di Venanzio, Gisela, Kinsella, Rachel L., Webb, Andrew I., Scott, Nichollas E., Pachón, Jerónimo, Feldman, Mario F.

“…Pathogenic Acinetobacter species, including Acinetobacter baumannii and Acinetobacter nosocomialis, are opportunistic human pathogens of increasing relevance…”
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Phenotypic changes associated with Colistin resistance due to Lipopolysaccharide loss in Acinetobacter baumannii by Carretero-Ledesma, Marta, García-Quintanilla, Meritxell, Martín-Peña, Reyes, Pulido, Marina R., Pachón, Jerónimo, McConnell, Michael J.

“…Acinetobacter baumannii can acquire resistance to colistin via complete loss of lipopolysaccharide (LPS) biosynthesis due to mutations in the lpxA, lpxC and…”
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Synergistic Effect of SOS Response and GATC Methylome Suppression on Antibiotic Stress Survival in Escherichia coli by Diaz-Diaz, S, Recacha, E, Pulido, Marina R, Romero-Muñoz, María, de Gregorio-Iaria, B, Docobo-Pérez, F, Pascual, A, Rodríguez-Martínez, J M

“…The suppression of the SOS response has been shown to enhance the activity of quinolones. Furthermore, Dam-dependent base methylation has an impact on…”
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Heterogeneity of SOS response expression in clinical isolates of Escherichia coli influences adaptation to antimicrobial stress by Diaz-Diaz, Sara, Garcia-Montaner, Andrea, Vanni, Roberta, Murillo-Torres, Marina, Recacha, Esther, Pulido, Marina R., Romero-Muñoz, Maria, Docobo-Pérez, Fernando, Pascual, Alvaro, Rodriguez-Martinez, Jose Manuel

“…In recent years, new evidence has shown that the SOS response plays an important role in the response to antimicrobials, with involvement in the generation of…”
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Vaccines for Antibiotic-Resistant Bacteria: Possibility or Pipe Dream? by García-Quintanilla, Meritxell, Pulido, Marina R, Carretero-Ledesma, Marta, McConnell, Michael J

“…The increasing incidence of infections caused by antibiotic-resistant bacteria from multiple species, together with the paucity of new antibiotics in the…”
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RecA inactivation as a strategy to reverse the heteroresistance phenomenon in clinical isolates of Escherichia coli by Diaz-Diaz, S., Yerbes, Pilar, Recacha, E., de Gregorio-Iaria, B., Pulido, Marina R., Romero-Muñoz, María, Docobo-Pérez, F., Pascual, A., Rodríguez-Martínez, J.M.

“…•Clinical heteroresistance is associated with acquired resistance gene copy number.•Clinical heteroresistance is dependent on RecA activity.•RecA constitutes a…”
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Impact of metronomic trabectedin combined with low-dose cyclophosphamide on sarcoma microenvironment and correlation with clinical outcome: results from the TARMIC study by Sun, Cheng-Ming, Toulmonde, Maud, Spalato-Ceruso, Mariella, Peyraud, Florent, Bessede, Alban, Kind, Michèle, Cousin, Sophie, Buy, Xavier, Palussiere, Jean, Bougouin, Antoine, Sautès-Fridman, Catherine, Fridman, Hervé Wolf, Pulido, Marina, Italiano, Antoine

“…Soft tissue sarcomas (STS) are diverse mesenchymal tumors with few therapeutic options in advanced stages. Trabectedin has global approval for treating STS…”
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The L-α-Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity by MORENO-NAVARRETE, José Maria, CATALAN, Victoria, IMBERNON, Mónica, ROSS, Ruth A, MALAGON, Maria M, DIEGUEZ, Carlos, FERNANDEZ-REAL, Jose Manuel, FRÜHBECK, Gema, NOGUEIRAS, Ruben, WHYTE, Lauren, DIAZ-ARTEAGA, Adenis, VAZQUEZ-MARTINEZ, Rafael, ROTELLAR, Fernando, GUZMAN, Rocio, GOMEZ-AMBROSI, Javier, PULIDO, Marina R, RUSSELL, Wendy R

“…GPR55 is a putative cannabinoid receptor, and l-α-lysophosphatidylinositol (LPI) is its only known endogenous ligand. We investigated 1) whether GPR55 is…”
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