Search Results - "Pulido, E J"

Therapeutic implications of interleukin-10 in surgical disease by Selzman, C H, Shames, B D, Miller, S A, Pulido, E J, Meng, X, McIntyre, Jr, R C, Harken, A H

“…Pharmacological therapy of surgical disease often involves manipulating the physiologic balance between pro- and anti-inflammatory responses. Many agents…”
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The Biology of Estrogen-Mediated Repair of Cardiovascular Injury by Selzman, Craig H, Whitehill, Thomas A, Shames, Brian D, Pulido, Edward J, Cain, Brian C, Harken, Alden H

“…Women appear to be protected from cardiovascular disease until the onset of menopause. Considerable evidence supports the atheroprotective effects of…”
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Cardiotrophin-1 Attenuates Endotoxin-Induced Acute Lung Injury by Pulido, Edward J., Shames, Brian D., Pennica, Diane, O'Leary, Rhona M., Bensard, Denis D., Cain, Brian S., McIntyre, Robert C.

“…Cardiotrophin-1 (CT-1) is a recently discovered member of the gp130 cytokine family, which includes IL-6, IL-11, leukemia inhibitory factor, ciliary…”
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Thirty years of clinical trials in acute respiratory distress syndrome by McIntyre, Robert C, Pulido, Edward J, Bensard, Denis D, Shames, Brian D, Abraham, Edward

“…OBJECTIVETo systematically review clinical trials in acute respiratory distress syndrome (ARDS). DATA SOURCESComputerized bibliographic search of published…”
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Neutralization of IL-18 Reduces Neutrophil Tissue Accumulation and Protects Mice Against Lethal Escherichia coli and Salmonella typhimurium Endotoxemia by Netea, Mihai G, Fantuzzi, Giamila, Kullberg, Bart Jan, Stuyt, Rogier J. L, Pulido, Edward J, McIntyre, Robert C., Jr, Joosten, Leo A. B, Van der Meer, Jos W. M, Dinarello, Charles A

“…In addition to stimulating IFN-gamma synthesis, IL-18 also possesses inflammatory effects by inducing synthesis of the proinflammatory cytokines TNF and…”
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Chemokines as mediators of diseases related to surgical conditions by Shames, B D, Zallen, G S, McIntyre, Jr, R C, Bensard, D D, Pulido, E J, Miller, S A, Pomerantz, B J, Selzman, C H, Meng, X, Harken, A H

“…Chemokines are important mediators of inflammation. Animal studies suggest that inhibition of chemokine action results in a decrease in inflammation. Novel…”
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Therapeutic Antidysrhythmic and Functional Protection in Human Atria by Cain, Brian S., Meldrum, Daniel R., Meng, Xianzhong, Pulido, Edward J., Banerjee, Anirban, Harken, Alden H.

“…Approximately 30% of patients suffer supraventricular dysrhythmias after cardiac bypass. While the heart can be constructively preconditioned to maintain…”
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Exogenous Calcium Preconditions Myocardium from Patients Taking Oral Sulfonylurea Agents by Cain, Brian S., Meldrum, Daniel R., Meng, Xianzhong, Pulido, Edward J., Shames, Brian D., Selzman, Craig H., Banerjee, Anirban, Harken, Alden H.

“…We have previously reported that atrial trabeculae from patients taking oral sulfonylurea hypoglycemic agents cannot be preconditioned by transient ischemia,…”
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LPS-Induced NF-κB Activation and TNF-α Release in Human Monocytes Are Protein Tyrosine Kinase Dependent and Protein Kinase C Independent by Shames, Brian D., Selzman, Craig H., Pulido, Edward J., Meng, Xianzhong, Meldrum, Daniel R., McIntyre, Robert C., Harken, Alden H., Banerjee, Anirban

“…Background.Tumor necrosis factor alpha (TNF-α) is an important mediator of septic shock. Endotoxin (LPS) signal transduction in human monocytes leads to…”
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L-arginine attenuates lipopolysaccharide-induced lung chemokine production by Calkins, C M, Bensard, D D, Heimbach, J K, Meng, X, Shames, B D, Pulido, E J, McIntyre, Jr, R C

“…Chemokines stimulate the influx of leukocytes into tissues. Their production is regulated by nuclear factor-kappaB (NF-kappaB), an inducible transcription…”
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Differential inducible nitric oxide synthase expression in systemic and pulmonary vessels after endotoxin by Pulido, E J, Shames, B D, Fullerton, D A, Sheridan, B C, Selzman, C H, Gamboni-Robertson, F, Bensard, D D, McIntyre, Jr, R C

“…Inducible nitric oxide synthase (iNOS) is associated with vascular hypocontractility in systemic vessels after endotoxin lipopolysaccharide (LPS)…”
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Inhibition of PARS attenuates endotoxin-induced dysfunction of pulmonary vasorelaxation by Pulido, E J, Shames, B D, Selzman, C H, Barton, H A, Banerjee, A, Bensard, D D, McIntyre, Jr, R C

“…Endotoxin (Etx) causes excessive activation of the nuclear repair enzyme poly(ADP-ribose) synthase (PARS), which depletes cellular energy stores and leads to…”
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Adrenergic induction of bimodal myocardial protection: signal transduction and cardiac gene reprogramming by Meng, X, Shames, B D, Pulido, E J, Meldrum, D R, Ao, L, Joo, K S, Harken, A H, Banerjee, A

“…This study tested the hypothesis that in vivo norepinephrine (NE) treatment induces bimodal cardiac functional protection against ischemia and examined the…”
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Endotoxin Differentially Impairs Receptor-Mediated Relaxation in Rat Isolated Pulmonary and Thoracic Aortic Vessels by McIntyre, Robert C., Pulido, Edward J., Sheridan, Brett, Meldrum, Daniel R., Bensard, Denis D., Fullerton, David A.

“…PURPOSEThe purpose of this study was to determine the effect of endotoxin on vasorelaxation in the pulmonary and systemic circulations in response to the…”
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Interleukin-10 stabilizes inhibitory kappaB-alpha in human monocytes by Shames, B D, Selzman, C H, Meldrum, D R, Pulido, E J, Barton, H A, Meng, X, Harken, A H, McIntyre, Jr, R C

“…Interleukin-10 (IL-10) protects animals from lethal endotoxemia. This beneficial effect is mediated, in part, by inhibition of inflammatory cytokine…”
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Suppression of Tumor Necrosis Factor α Production by cAMP in Human Monocytes: Dissociation with mRNA Level and Independent of Interleukin-10 by Shames, Brian D., McIntyre, Robert C., Bensard, Denis D., Pulido, Edward J., Selzman, Craig H., Reznikov, Leonid L., Harken, Alden H., Meng, Xianzhong

“…Background. Elevation of cellular cAMP inhibits lipopolysaccharide(LPS)-stimulated tumor necrosis factor α (TNF-α) production and increases the expression of…”
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LPS-Induced NF-kappaB activation and TNF-alpha release in human monocytes are protein tyrosine kinase dependent and protein kinase C independent by Shames, B D, Selzman, C H, Pulido, E J, Meng, X, Meldrum, D R, McIntyre, Jr, R C, Harken, A H, Banerjee, A

“…Tumor necrosis factor alpha (TNF-alpha) is an important mediator of septic shock. Endotoxin (LPS) signal transduction in human monocytes leads to activation of…”
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Increased levels of myocardial IkappaB-alpha protein promote tolerance to endotoxin by Shames, B D, Meldrum, D R, Selzman, C H, Pulido, E J, Cain, B S, Banerjee, A, Harken, A H, Meng, X

“…Endotoxin [lipopolysaccharide (LPS)] causes tumor necrosis factor-alpha (TNF-alpha)-mediated myocardial contractile depression. Tolerance to the cardiac…”
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IL-1 regulates in vivo C-X-C chemokine induction and neutrophil sequestration following endotoxemia by Calkins, Casey M, Bensard, Denis D, Shames, Brian D, Pulido, Edward J, Abraham, Edward, Fernandez, Nathan, Meng, Xianzhong, Dinarello, Charles A, McIntyre, Jr, Robert C

“…The influx of neutrophils into tissues in response to inflammatory stimuli involves C-X-C chemokines. Interleukin-1 (IL-1) stimulates chemokine production in…”
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L-arginine in the control of lung chemokine production by Das, Undurti

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