Search Results - "Pujic, Zac"

Spontaneous and evoked activity patterns diverge over development by Avitan, Lilach, Pujic, Zac, Mölter, Jan, Zhu, Shuyu, Sun, Biao, Goodhill, Geoffrey J

“…The immature brain is highly spontaneously active. Over development this activity must be integrated with emerging patterns of stimulus-evoked activity, but…”
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Behavioral Signatures of a Developing Neural Code by Avitan, Lilach, Pujic, Zac, Mölter, Jan, McCullough, Michael, Zhu, Shuyu, Sun, Biao, Myhre, Ann-Elin, Goodhill, Geoffrey J.

“…During early life, neural codes must develop to appropriately transform sensory inputs into behavioral outputs. Here, we demonstrate a link between the…”
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Model-based decoupling of evoked and spontaneous neural activity in calcium imaging data by Triplett, Marcus A, Pujic, Zac, Sun, Biao, Avitan, Lilach, Goodhill, Geoffrey J

“…The pattern of neural activity evoked by a stimulus can be substantially affected by ongoing spontaneous activity. Separating these two types of activity is…”
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Control of neurite growth and guidance by an inhibitory cell-body signal by Bicknell, Brendan A, Pujic, Zac, Dayan, Peter, Goodhill, Geoffrey J

“…The development of a functional nervous system requires tight control of neurite growth and guidance by extracellular chemical cues. Neurite growth is…”
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Retraction: A mathematical model explains saturating axon guidance responses to molecular gradients by Nguyen, Huyen, Dayan, Peter, Pujic, Zac, Cooper-White, Justin, Goodhill, Geoffrey J

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A mathematical model explains saturating axon guidance responses to molecular gradients by Nguyen, Huyen, Dayan, Peter, Pujic, Zac, Cooper-White, Justin, Goodhill, Geoffrey J

“…Correct wiring is crucial for the proper functioning of the nervous system. Molecular gradients provide critical signals to guide growth cones, which are the…”
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Bayesian model predicts the response of axons to molecular gradients by Mortimer, Duncan, Feldner, Julia, Vaughan, Timothy, Vetter, Irina, Pujic, Zac, Rosoff, William J, Burrage, Kevin, Dayan, Peter, Richards, Linda J, Goodhill, Geoffrey J

“…Axon guidance by molecular gradients plays a crucial role in wiring up the nervous system. However, the mechanisms axons use to detect gradients are largely…”
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Axon guidance by growth-rate modulation by Mortimer, Duncan, Pujic, Zac, Vaughan, Timothy, Thompson, Andrew W, Feldner, Julia, Vetter, Irina, Goodhill, Geoffrey J

“…Guidance of axons by molecular gradients is crucial for wiring up the developing nervous system. It often is assumed that the unique signature of such guidance…”
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Zebrafish Chromosome 14 Gene Differential Expression in the fmr1hu2787 Model of Fragile X Syndrome by Barthelson, Karissa, Baer, Lachlan, Dong, Yang, Hand, Melanie, Pujic, Zac, Newman, Morgan, Goodhill, Geoffrey J., Richards, Robert I., Pederson, Stephen M., Lardelli, Michael

“…Zebrafish represent a valuable model for investigating the molecular and cellular basis of Fragile X syndrome (FXS). Reduced expression of the zebrafish FMR1…”
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Zebrafish N-cadherin, encoded by the glass onion locus, plays an essential role in retinal patterning by Malicki, Jarema, Jo, Hakryul, Pujic, Zac

“…Genetic screens in zebrafish identified several loci that play essential roles in the patterning of retinal architecture. Here, we show that one of them, glass…”
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RETRACTED: A mathematical model explains saturating axon guidance responses to molecular gradients by Nguyen, Huyen, Dayan, Peter, Pujic, Zac, Cooper-White, Justin, Goodhill, Geoffrey J

“…Correct wiring is crucial for the proper functioning of the nervous system. Molecular gradients provide critical signals to guide growth cones, which are the…”
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Mutation of the Zebrafish glass onion Locus Causes Early Cell-Nonautonomous Loss of Neuroepithelial Integrity Followed by Severe Neuronal Patterning Defects in the Retina by Pujic, Zac, Malicki, Jarema

“…Mutation of the glass onion locus causes drastic neuronal patterning defects in the zebrafish retina and brain. The precise stratified appearance of the…”
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Assays for eukaryotic cell chemotaxis by Pujic, Zac, Mortimer, Duncan, Feldner, Julia, Goodhill, Geoffrey J

“…Chemotaxis is essential for many biological processes. Much of our understanding of the mechanisms underlying chemotaxis is based on a variety of in vitro…”
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Analysis of gene function in the zebrafish retina by Malicki, Jarema, Jo, Hakryul, Wei, Xiangyun, Hsiung, Monica, Pujic, Zac

“…Mutagenesis screens in zebrafish have uncovered several hundred mutant alleles affecting the development of the retina and established the zebrafish as one of…”
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Forward and reverse genetic approaches to the analysis of eye development in zebrafish by Malicki, Jarema J, Pujic, Zac, Thisse, Christine, Thisse, Bernard, Wei, Xiangyun

“…The zebrafish has been established as a mainstream research system, largely due to the immense success of genetic screens. Over 2000 mutant alleles affecting…”
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Calcium signaling in axon guidance by Sutherland, Daniel J, Pujic, Zac, Goodhill, Geoffrey J

“…Highlights • Calcium signaling is crucial for guiding axons to their targets. • Calcium enters the growth cone through several different routes. • The calcium…”
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Spontaneous Activity in the Zebrafish Tectum Reorganizes over Development and Is Influenced by Visual Experience by Avitan, Lilach, Pujic, Zac, Mölter, Jan, Van De Poll, Matthew, Sun, Biao, Teng, Haotian, Amor, Rumelo, Scott, Ethan K., Goodhill, Geoffrey J.

“…Spontaneous patterns of activity in the developing visual system may play an important role in shaping the brain for function. During the period 4–9 dpf (days…”
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fmr1 Mutation Alters the Early Development of Sensory Coding and Hunting and Social Behaviors in Larval Zebrafish by Zhu, Shuyu I, McCullough, Michael H, Pujic, Zac, Sibberas, Jordan, Sun, Biao, Darveniza, Thomas, Bucknall, Bianca, Avitan, Lilach, Goodhill, Geoffrey J

“…Autism spectrum disorders (ASDs) are developmental in origin; however, little is known about how they affect the early development of behavior and sensory…”
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Behavioral Signatures of a Developing Neural Code by Avitan, Lilach, Pujic, Zac, Mölter, Jan, McCullough, Michael, Zhu, Shuyu, Sun, Biao, Myhre, Ann-Elin, Goodhill, Geoffrey J.

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Limitations of Neural Map Topography for Decoding Spatial Information by Avitan, Lilach, Pujic, Zac, Hughes, Nicholas J, Scott, Ethan K, Goodhill, Geoffrey J

“…Topographic maps are common throughout the nervous system, yet their functional role is still unclear. In particular, whether they are necessary for decoding…”
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