Search Results - "Puijk, W C"

Mimotopes: realization of an unlikely concept by Meloen, R. H., Puijk, W. C., Slootstra, J. W.

“…Theoretically it seems highly unlikely that relatively small peptides could mimic functionally discontinuous epitopes of antigens. Nevertheless various recent…”
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Design of synthetic peptides for diagnostics by Meloen, R H, Puijk, W C, Langeveld, J P M, Langedijk, J P M, Timmerman, P

“…Due to the advantageous properties of synthetic molecules compared to biological ones biological molecules in diagnostic tests are replaced increasingly by…”
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First peptide vaccine providing protection against viral infection in the target animal: studies of canine parvovirus in dogs by LANGEVELD, J. P. M, CASAL, J. I, OSTERHAUS, A. D. M. E, CORTES, E, DE SWART, R, VELA, C, DALSGAARD, K, PUIJK, W. C, SCHAAPER, W. M. M, MELOEN, R. H

“…A synthetic peptide vaccine which protects dogs against challenge with virulent canine parvovirus is described. The amino acid sequence used was discovered in…”
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Identification of epitopes within beta lactoglobulin recognised by polyclonal antibodies using phage display and PEPSCAN by Williams, S.C, Badley, R.A, Davis, P.J, Puijk, W.C, Meloen, R.H

“…Two different epitope mapping techniques were used to identify linear epitopes recognised by polyclonal IgG antibodies from rabbits immunised with bovine beta…”
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Efficient immunocastration of male piglets by immunoneutralization of GnRH using a new GnRH-like peptide by Meloen, R H, Turkstra, J A, Lankhof, H, Puijk, W C, Schaaper, W M, Dijkstra, G, Wensing, C J, Oonk, R B

“…Active immunization to immunomodulate regulatory processes suffers from the disadvantage that the antigen is usually 'self' and therefore poorly immunogenic…”
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B-cell epitopes of canine parvovirus: distribution on the primary structure and exposure on the viral surface by Langeveld, J.P.M. (Central Veterinary Institute, Lelystad, The Netherlands), Casal, J.I, Vela, C, Dalsgaard, K, Smale, S.H, Puijk, W.C, Meloen, R.H

“…Ten antigenic sites on canine parvovirus (CPV) were mapped with a complete set of overlapping nonapeptides of the capsid proteins Vp1 and VP2: five of these…”
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In vitro inhibition of the biological activity of follicle-stimulating hormone by anti-peptide antisera representing the human follicle-stimulating hormone beta subunit sequence 33-53 by WESTHOFF, W. E, SLOOTSTRA, J. W, PUIJK, W. C, VAN LEEUWEN, L, SCHAAPER, W. M. M, OONK, H. B, MELOEN, R. H

“…There are few male contraceptive methods, and research is required to broaden the scope of available male antifertility methods. Two approaches toward hormonal…”
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Induction of HIV-1 IIIb neutralizing antibodies in BALB/c mice by a chimaeric peptide consisting of a T-helper cell epitope of Semliki Forest virus and a B-cell epitope of HIV by FERNANDEZ, I. M, GOLDING, H, KRAAIJEVELD, C. A, BENAISSA-TROUW, B. J, DE VOS, N. M, HARMSEN, M, NOTTET, H. S. L. M, GOLDING, B, PUIJK, W. C, MELOEN, R. H, SNIPPE, H

“…A colinearly synthesized peptide consisting of a H-2d restricted T-helper cell epitope of Semliki Forest virus (SFV) and triple repeats of sequence GPGRAF,…”
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Location of CD4 dimerization site explains critical role of CDR3-like region in HIV-1 infection and T-cell activation and implies a model for complex of coreceptor-MHC by Langedijk, J P, Puijk, W C, van Hoorn, W P, Meloen, R H

“…CD4 cross-linking by antibodies or its natural ligands triggers a tyrosine kinase activity that is one of the necessary steps in the mechanism of human…”
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Structural aspects of antibody-antigen interaction revealed through small random peptide libraries by Slootstra, J W, Puijk, W C, Ligtvoet, G J, Langeveld, J P, Meloen, R H

“…Two small random peptide libraries, one composed of 4550 dodecapeptides and one of 8000 tripeptides, were synthesized in newly developed credit-card format…”
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Identification and Characterization of Heparin Binding Regions of the Fim2 Subunit of Bordetella pertussis by GEUIJEN, C. A. W, WILLEMS, R. J. L, HOOGERHOUT, P, PUIJK, W. C, MELOEN, R. H, MOOI, F. R

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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In vitro inhibition of the bioactivity of follicle-stimulating hormone by antisera against a peptide representing part of the FSH-receptor by Zijlstra-Westhoff, W.E, Slootstra, J.W, Puijk, W.C, Schaaper, W.M.M, Oonk, H.B, Meloen, R.H

“…The aim of the present work was to define an FSH receptor (FSHR) peptide that can induce antibodies that will inhibit the bioactivity of FSH. Therefore, the…”
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Synthetic Peptides Based Upon a Three-Dimensional Model for the Receptor Recognition Site of Follicle-Stimulating Hormone Exhibit Antagonistic or Agonistic Activity at Low Concentrations by Noort, M. Hage-van, Puijk, W. C., Plasman, H. H., Kuperus, D., Schaaper, W. M. M., N. J. C. M. Beekman, Grootegoed, J. A., Meloen, R. H.

“…Follicle-stimulating hormone (follitropin, FSH) belongs to a group of closely related glycoprotein hormones that contain two noncovalently linked dissimilar…”
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Manipulation of antipeptide immune response by varying the coupling of the peptide with the carrier protein by Schaaper, W M, Lankhof, H, Puijk, W C, Meloen, R H

“…Antibodies were raised against synthetic peptides of two regions of the surface protein VP1 of foot-and-mouth disease virus. The peptides were conjugated with…”
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Identification of linear epitopes on Semliki Forest virus E2 membrane protein and their effectiveness as a synthetic peptide vaccine by Snijders, Alies, Benaissa-Trouw, Barry J, Oosterlaken, Tom A. M, Puijk, Wouter C, Posthumus, Willem P. A, Meloen, Rob H, Boere, Wil A. M, Oosting, Janine D, Kraaijeveld, Cornelis A, Snippe, Harm

“…1 Eijkman-Winkler Laboratory of Medical Microbiology, Academic Hospital Utrecht, HP G04.614, Postbox 85500, 3508 GA Utrecht and 2 Central Veterinary Institute,…”
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Functional Reconstruction of Structurally Complex Epitopes using CLIPS™ Technology by Timmerman, P., Puijk, W. C., Boshuizen, R. S., Dijken, P.van, Slootstra, J. W., Beurskens, F. J., Parren, P.W. H.I., Huber, A., Bachmann, M. F., Meloen, R. H.

“…This review summarizes an illustrative set of data from our research on the reconstruction of structurally complex protein surfaces, i.e. those that fail to be…”
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Peptide transport by the multidrug resistance protein MRP1 by DE JONG, Mariska C, SLOOTSTRA, Jerry W, SCHEFFER, George L, SCHROEIJERS, Anouk B, PUIJK, Wouter C, DINKELBERG, Remco, KOOL, Marcel, BROXTERMAN, Henk J, MELOEN, Rob H, SCHEPER, Rik J

“…Small hydrophobic peptides were studied as possible substrates of the multidrug resistance protein (MRP)-1 (ABCC1) transmembrane transporter molecule. As…”
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Detection of epitopes on follicle-stimulating hormone and FSH-antiserum-induced suppression of bioactivity of follicle-stimulating hormone and luteinizing hormone by Westhoff, W.E., Slootstra, J.W., Puijk, W.C., Kuperus, D., Flinterman, J.F., Schaaper, W.M.M., Oonk, H.B., Meloen, R.H.

“…There are currently two major approaches to hormonal male contraception. One relies on testosterone (analogs) either alone or in combination with gonadotropin…”
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Comparative studies of tyrosine modification in pancreatic phospholipases. 2. Properties of the nitrotyrosyl, aminotyrosyl, and dansylaminotyrosyl derivatives of pig, horse, and ox phospholipases A2 and their zymogens by Meyer, H, Puijk, W. C, Dijkman, R, Foda-van der Hoorn, M. M. E. L, Pattus, F, Slotboom, A. J, De Haas, G. H

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Screening of a Small Set of Random Peptides: A New Strategy to Identify Synthetic Peptides that Mimic Epitopes by Sloostra, J. W., Puijk, W. C., Ligvoet, G. J., Kuperus, D., Schaaper, W. M. M., Meloen, R. H.

“…Small diversity libraries, composed of 4550 synthetic dodecapeptides and 8000 synthetic tripeptides, have been used to identify sequences homologous to small…”
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