Search Results - "Puiggros, Sergi Roig"
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Synergistic Activity of Floor-Plate- and Ventricular-Zone-Derived Netrin-1 in Spinal Cord Commissural Axon Guidance
Published in Neuron (Cambridge, Mass.) (20-02-2019)“…In vertebrates, commissural axons extend ventrally toward the floor plate in the spinal cord and hindbrain. Netrin-1, secreted by floor plate cells, was…”
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Uncoupling axon guidance and neuronal migration in Robo3‐deficient inferior olivary neurons
Published in Journal of comparative neurology (1911) (01-11-2022)“…Inferior olivary (IO) neurons are born in the dorsal hindbrain and migrate tangentially toward the ventral midline. During their dorsoventral migration, IO…”
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Commissural neurons transgress the CNS/PNS boundary in absence of ventricular zone-derived netrin 1
Published in Development (Cambridge) (15-01-2018)“…During the development of the central nervous system (CNS), only motor axons project into peripheral nerves. Little is known about the cellular and molecular…”
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Loss of floor plate Netrin-1 impairs midline crossing of corticospinal axons and leads to mirror movements
Published in Cell reports (Cambridge) (19-01-2021)“…In humans, execution of unimanual movements requires lateralized activation of the primary motor cortex, which then transmits the motor command to the…”
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THE ROLE OF NETRIN-1 IN MOUSE CEREBELLAR DEVELOPMENT
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Light-dependent development is tailored in visual neurons
Published in Nature (London) (03-03-2022)“…When mouse pups first open their eyes, what they see shapes neuronal connectivity. A study shows that this visual experience has cell-type-specific effects,…”
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Visual identity isn't a light decision for all neurons
Published in Nature (London) (03-03-2022)“…Writing in Cell, Cheng etal.4 take on this challenge by investigating how postnatal visual experience affects distinct neuronal cell types in the maturing…”
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Floor-plate-derived netrin-1 is dispensable for commissural axon guidance
Published in Nature (London) (18-05-2017)“…Preventing netrin secretion from floor-plate cells at the midline does not disrupt axonal guidance; commissural axons develop normally and the data suggest…”
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Molecular programs guiding arealization of descending cortical pathways
Published in Nature (London) (17-10-2024)“…Layer 5 extratelencephalic (ET) neurons are present across neocortical areas and send axons to multiple subcortical targets 1 – 6 . Two cardinal subtypes exist…”
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Construction and reconstruction of brain circuits: normal and pathological axon guidance
Published in Journal of neurochemistry (01-04-2020)“…Perception of our environment entirely depends on the close interaction between the central and peripheral nervous system. In order to communicate each other,…”
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