Search Results - "Puig, Luis"
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Tyk2 Targeting in Immune-Mediated Inflammatory Diseases
Published in International journal of molecular sciences (01-02-2023)“…The Janus kinase (Jak)/signal transducer and activating protein (STAT) pathways mediate the intracellular signaling of cytokines in a wide spectrum of cellular…”
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Long-term efficacy and safety of brodalumab in the treatment of psoriasis: 120-week results from the randomized, double-blind, placebo- and active comparator–controlled phase 3 AMAGINE-2 trial
Published in Journal of the American Academy of Dermatology (01-02-2020)“…Randomized controlled trials have shown the efficacy and safety of brodalumab in patients with moderate to severe plaque psoriasis. To evaluate the efficacy…”
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Risk Factors for Degree and Type of Sequelae After Involution of Untreated Hemangiomas of Infancy
Published in JAMA dermatology (Chicago, Ill.) (01-11-2016)“…Infantile hemangiomas involute to some extent, but they often leave sequelae that may cause disfigurement. Factors determining the risk of permanent sequelae…”
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Psoriasis and Systemic Inflammatory Diseases: Potential Mechanistic Links between Skin Disease and Co-Morbid Conditions
Published in Journal of investigative dermatology (01-07-2010)“…Psoriasis is now classified as an immune-mediated inflammatory disease (IMID) of the skin. It is being recognized that patients with various IMIDs, including…”
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Impact of ixekizumab on psoriasis itch severity and other psoriasis symptoms: Results from 3 phase III psoriasis clinical trials
Published in Journal of the American Academy of Dermatology (01-12-2016)“…Background Itch is a prevalent symptom of psoriasis that impacts quality of life. Objective We sought to describe improvements in itch severity, skin pain, and…”
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Generalized Pustular Psoriasis: A Review on Clinical Characteristics, Diagnosis, and Treatment
Published in Dermatology and therapy (01-03-2023)“…Generalized pustular psoriasis (GPP) is a rare, chronic, and severe inflammatory skin disorder characterized by sudden eruption of sterile pustules, often…”
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Nomenclature and clinical phenotypes of atopic dermatitis
Published in Therapeutic advances in chronic disease (2021)“…Atopic dermatitis is a heterogeneous disease and resists classification. In this review, we discuss atopic dermatitis nomenclature and identify morphologic…”
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The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases
Published in Frontiers in immunology (04-08-2023)“…Interleukin-17 family (IL-17s) comprises six structurally related members (IL-17A to IL-17F); sequence homology is highest between IL-17A and IL-17F,…”
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Predictors of Local Invasion in Infiltrative Basal Cell Carcinoma: Tumour Budding Outperforms the WHO Subtyping
Published in Acta dermato-venereologica (02-07-2024)“…Tumour budding (TB) correlates with increased local invasion in various neoplasms. Certain basal cell carcinomas (BCCs) exhibit local aggressiveness. Detecting…”
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Network meta-analyses comparing the efficacy of biologic treatments for achieving complete resolution of nail psoriasis at 24–28 and 48–52 weeks
Published in The Journal of dermatological treatment (31-12-2023)“…BACKGROUNDAvailable network meta-analyses (NMAs) comparing the efficacy of biologics in nail psoriasis (NP) have not included recently approved biologics such…”
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Comparative Efficacy and Relative Ranking of Biologics and Oral Therapies for Moderate-to-Severe Plaque Psoriasis: A Network Meta-analysis
Published in Dermatology and therapy (01-06-2021)“…Introduction The clinical benefits of biologic and oral treatments for moderate-to-severe plaque psoriasis are well-established, but efficacy outcomes can vary…”
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PsoBarrier EU study: a Multicentre, Cross-sectional Survey Investigating the Quality of Psoriasis Care in Four European Countries
Published in Acta dermato-venereologica (31-08-2023)“…Enhanced treatment options for psoriasis and growing use of guidelines increased the potential to better quality of psoriasis care in Europe. The aim of the…”
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Real-World Discontinuation and Switching Patterns for Interleukin-Inhibitor Treatments in Patients with Moderate-to-Severe Psoriasis in Japan
Published in Dermatology and therapy (01-01-2024)“…Introduction Patients with moderate-to-severe psoriasis (PsO) treated with interleukin (IL)-inhibitors may require treatment modification to achieve disease…”
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Calibration of omnidirectional cameras in practice: A comparison of methods
Published in Computer vision and image understanding (2012)“…► Survey of four calibration methods for central catadioptric systems. ► Three different central catadioptric systems and one non-central fish-eye lens were…”
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Drug survival of conventional systemic and biologic therapies for moderate-to-severe psoriasis in clinical practice in Spain: prospective results from the SAHARA study
Published in The Journal of dermatological treatment (18-05-2020)“…Background: A better understanding of determinants for drug survival of antipsoriatic agents may guide dermatologists in the right therapeutic choice…”
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Increasing Access to Effective Systemic Treatments in Patients with Moderate-to-Severe Psoriasis: Narrative Review
Published in Dermatology and therapy (01-10-2023)“…Psoriasis is a chronic, immune-mediated inflammatory disease with a worldwide prevalence ranging between 0.51 and 11.43%. It results in a large clinical and…”
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Safety of Ixekizumab Treatment for up to 5 Years in Adult Patients with Moderate-to-Severe Psoriasis: Results from Greater Than 17,000 Patient-Years of Exposure
Published in Dermatology and therapy (01-02-2020)“…Introduction Long-term safety data are critical for evaluating therapies for psoriasis. Ixekizumab has demonstrated efficacy and is well tolerated for the…”
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Real-World Long-Term Effectiveness of Risankizumab Among Patients with Moderate-to-Severe Psoriasis: Analysis from an International Medical Chart Review (RAPID) Study
Published in Dermatology and therapy (01-05-2024)“…Introduction Real-world data on the efficacy of risankizumab (RZB) in clinical moderate-to-severe plaque psoriasis (PsO) are limited. The RAPID study assessed…”
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IL-1 Family Cytokines in Inflammatory Dermatoses: Pathogenetic Role and Potential Therapeutic Implications
Published in International journal of molecular sciences (22-08-2022)“…The interleukin-1 (IL-1) family is involved in the correct functioning and regulation of the innate immune system, linking innate and adaptative immune…”
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Pimecrolimus in atopic dermatitis: Consensus on safety and the need to allow use in infants
Published in Pediatric allergy and immunology (01-06-2015)“…Atopic dermatitis (AD) is a distressing dermatological disease, which is highly prevalent during infancy, can persist into later life and requires long‐term…”
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