Search Results - "Puhger, Kyle"
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An expanded palette of dopamine sensors for multiplex imaging in vivo
Published in Nature methods (01-11-2020)“…Genetically encoded dopamine sensors based on green fluorescent protein (GFP) enable high-resolution imaging of dopamine dynamics in behaving animals. However,…”
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Journal Article -
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Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus
Published in eLife (09-04-2024)“…Locus coeruleus (LC) projections to the hippocampus play a critical role in learning and memory. However, the precise timing of LC-hippocampus communication…”
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Journal Article -
3
SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function
Published in Cell reports (Cambridge) (27-02-2018)“…Altering AMPA receptor (AMPAR) content at synapses is a key mechanism underlying the regulation of synaptic strength during learning and memory. Previous work…”
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Journal Article -
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Amnesia for context fear is caused by widespread disruption of hippocampal activity
Published in Neurobiology of learning and memory (01-11-2020)“…The hippocampus plays an essential role in the formation and retrieval of episodic memories in humans and contextual memories in animals. However, amnesia is…”
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Journal Article -
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Acute Disruption of the Dorsal Hippocampus Impairs the Encoding and Retrieval of Trace Fear Memories
Published in Frontiers in behavioral neuroscience (29-05-2019)“…A major function of the hippocampus is to link discontiguous events in memory. This process can be studied in animals using Pavlovian trace conditioning, a…”
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Journal Article -
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Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine
Published in Neurotoxicology and teratology (01-01-2015)“…Abstract Tetramethylenedisulfotetramine (TETS) is a potent convulsant poison that is thought to trigger seizures by inhibiting the function of the type A…”
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Journal Article -
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The hippocampus contributes to retroactive stimulus associations during trace fear conditioning
Published in iScience (15-03-2024)“…Binding events that occur at different times are essential for memory formation. In trace fear conditioning, animals associate a tone and footshock despite no…”
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Journal Article -
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The Hippocampus Contributes to Retroactive Stimulus Associations
Published 01-01-2022“…Trace fear conditioning (TFC) is a variant of Pavlovian conditioning in which the CS and US are separated by a temporal gap (aka trace interval). The…”
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Dissertation -
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Phasic locus coeruleus activity enhances trace fear conditioning by increasing dopamine release in the hippocampus
Published in eLife (09-04-2024)“…Locus coeruleus (LC) projections to the hippocampus play a critical role in learning and memory. However, the precise timing of LC-hippocampus communication…”
Get full text
Journal Article