Search Results - "Pugliese, Steven"

The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes by Pugliese, Steven C, Poth, Jens M, Fini, Mehdi A, Olschewski, Andrea, El Kasmi, Karim C, Stenmark, Kurt R

“…Hypoxic pulmonary hypertension (PH) comprises a heterogeneous group of diseases sharing the common feature of chronic hypoxia-induced pulmonary vascular…”
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The Post-Pulmonary Embolism Syndrome: Real or Ruse? by Pugliese, Steven C, Kawut, Steven M

“…CPET = cardiopulmonary exercise testing; CTA = computed tomography angiography; CTEPH = chronic thromboembolic pulmonary hypertension; PVD = pulmonary vascular…”
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Suppression of HIF2 signalling attenuates the initiation of hypoxia-induced pulmonary hypertension by Hu, Cheng-Jun, Poth, Jens M, Zhang, Hui, Flockton, Amanda, Laux, Aya, Kumar, Sushil, McKeon, Brittany, Mouradian, Gary, Li, Min, Riddle, Suzette, Pugliese, Steven C, Brown, R Dale, Wallace, Eli M, Graham, Brian B, Frid, Maria G, Stenmark, Kurt R

“…Most published studies addressing the role of hypoxia inducible factors (HIFs) in hypoxia-induced pulmonary hypertension development employ models that may not…”
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Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension by El Kasmi, Karim C, Pugliese, Steven C, Riddle, Suzette R, Poth, Jens M, Anderson, Aimee L, Frid, Maria G, Li, Min, Pullamsetti, Soni S, Savai, Rajkumar, Nagel, Maria A, Fini, Mehdi A, Graham, Brian B, Tuder, Rubin M, Friedman, Jacob E, Eltzschig, Holger K, Sokol, Ronald J, Stenmark, Kurt R

“…Macrophage accumulation is not only a characteristic hallmark but is also a critical component of pulmonary artery remodeling associated with pulmonary…”
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Characteristics, Outcomes, and Trends of Patients With COVID-19-Related Critical Illness at a Learning Health System in the United States by Anesi, George L, Jablonski, Juliane, Harhay, Michael O, Atkins, Joshua H, Bajaj, Jasmeet, Baston, Cameron, Brennan, Patrick J, Candeloro, Christina L, Catalano, Lauren M, Cereda, Maurizio F, Chandler, John M, Christie, Jason D, Collins, Tara, Courtright, Katherine R, Fuchs, Barry D, Gordon, Emily, Greenwood, John C, Gudowski, Steven, Hanish, Asaf, Hanson, 3rd, C William, Heuer, Monica, Kinniry, Paul, Kornfield, Zev Noah, Kruse, Gregory B, Lane-Fall, Meghan, Martin, Niels D, Mikkelsen, Mark E, Negoianu, Dan, Pascual, Jose L, Patel, Maulik B, Pugliese, Steven C, Qasim, Zaffer A, Reilly, John P, Salmon, John, Schweickert, William D, Scott, Michael J, Shashaty, Michael G S, Sicoutris, Corinna P, Wang, John K, Wang, Wei, Wani, Arshad A, Anderson, Brian J, Gutsche, Jacob T

“…The coronavirus disease 2019 (COVID-19) pandemic continues to surge in the United States and globally. To describe the epidemiology of COVID-19-related…”
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A Time- and Compartment-Specific Activation of Lung Macrophages in Hypoxic Pulmonary Hypertension by Pugliese, Steven C, Kumar, Sushil, Janssen, William J, Graham, Brian B, Frid, Maria G, Riddle, Suzette R, El Kasmi, Karim C, Stenmark, Kurt R

“…Studies in various animal models suggest an important role for pulmonary macrophages in the pathogenesis of pulmonary hypertension (PH). Yet, the molecular…”
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Novel Liver Injury Phenotypes and Outcomes in Clinical Trial Participants with Pulmonary Hypertension by Scott, Jacqueline V, Moutchia, Jude, McClelland, Robin L, Al-Naamani, Nadine, Weinberg, Ethan, Palevsky, Harold I, Minhas, Jasleen, Appleby, Dina K, Smith, Akaya, Pugliese, Steven C, Ventetuolo, Corey E, Kawut, Steven M

“…Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) cause right ventricular dysfunction which can impact other…”
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Pulmonary artery compliance in different forms of pulmonary hypertension by McCormick, Amber, Krishnan, Amita, Badesch, David, Benza, Raymond L, Bull, Todd M, De Marco, Teresa, Feldman, Jeremy, Hemnes, Anna R, Hirsch, Russel, Horn, Evelyn, Kennedy, Jaime, Mathai, Stephen C, McConnell, Wesley, Pugliese, Steven C, Sager, Jeffrey S, Shlobin, Oksana A, Simon, Marc A, Lammi, Matthew R

“…Pulmonary artery compliance (PAC), estimated as stroke volume (SV) divided by pulmonary artery pulse pressure (PP), may be a predictor of survival in pulmonary…”
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Unexplained Dyspnea: Hepatopulmonary Syndrome without Cirrhosis? by De la Fuente, Justin Rafael O, Buckley, Laura K, Kawut, Steven M, Pugliese, Steven C

“…Kawut et al discuss the case of a 64-year-old man, with a history of hepatic steatosis and obstructive sleep apnea, who was referred for evaluation of…”
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BMI and Treatment Response in Patients With Pulmonary Arterial Hypertension: A Meta-analysis by McCarthy, Breanne E, McClelland, Robyn L, Appleby, Dina H, Moutchia, Jude S, Minhas, Jasleen K, Min, Jeff, Mazurek, Jeremy A, Smith, K Akaya, Fritz, Jason S, Pugliese, Steven C, Urbanowicz, Ryan J, Holmes, John H, Palevsky, Harold I, Kawut, Steven M, Al-Naamani, Nadine

“…Obesity is increasingly prevalent in pulmonary arterial hypertension (PAH) but is associated with improved survival, creating an "obesity paradox" in PAH. It…”
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Electrocardiographic Abnormalities and Their Association with Outcomes in Randomized Clinical Trials of Pulmonary Arterial Hypertension by Minhas, Jasleen, Moutchia, Jude, Al-Naamani, Nadine, Mazurek, Jeremy A, Holmes, John H, Appleby, Dina, Smith, K Akaya, Fritz, Jason S, Pugliese, Steven C, Palevsky, Harold I, Kawut, Steven M

“…Pulmonary arterial hypertension (PAH) is a progressive disease with manifestations including right atrial enlargement, right ventricular dysfunction, dilation,…”
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Racial, Ethnic, and Socioeconomic Inequities in the Prescription of Direct Oral Anticoagulants in Patients With Venous Thromboembolism in the United States by Nathan, Ashwin S, Geng, Zhi, Dayoub, Elias J, Khatana, Sameed Ahmed M, Eberly, Lauren A, Kobayashi, Taisei, Pugliese, Steven C, Adusumalli, Srinath, Giri, Jay, Groeneveld, Peter W

“…Beginning in 2012, direct oral anticoagulants (DOACs) were approved for treatment and prevention of venous thromboembolism. Prior investigations have…”
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Outcomes of catheter-directed versus systemic thrombolysis for the treatment of pulmonary embolism: A real-world analysis of national administrative claims by Geller, Bram J, Adusumalli, Srinath, Pugliese, Steven C, Khatana, Sameed Ahmed M, Nathan, Ashwin, Weinberg, Ido, Jaff, Michael R, Kobayashi, Taisei, Mazurek, Jeremy A, Khandhar, Sameer, Yang, Lin, Groeneveld, Peter W, Giri, Jay S

“…Catheter-directed thrombolysis (CDT) and systemic thrombolysis (ST) are used to treat intermediate/high-risk pulmonary embolism (PE) in the absence of…”
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Management of Acute Pulmonary Embolism by Tice, Connor, Seigerman, Matthew, Fiorilli, Paul, Pugliese, Steven C., Khandhar, Sameer, Giri, Jay, Kobayashi, Taisei

“…Purpose of the Review Over 100,000 cardiovascular-related deaths annually are caused by acute pulmonary embolism (PE). While anticoagulation has historically…”
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Health-related quality of life and hospitalizations in chronic thromboembolic pulmonary hypertension versus idiopathic pulmonary arterial hypertension: an analysis from the Pulmonary Hypertension Association Registry (PHAR) by Minhas, Jasleen, Narasimmal, Sai Prasanna, M. Bull, Todd, Marco, Teresa De, McConnell, John Wesley, Lammi, Matthew R., Thenappan, Thenappan, P. Feldman, Jeremy, S. Sager, Jeffrey, B. Badesch, David, Ryan, John J., C. Grinnan, Daniel, Zwicke, Dianne, M. Horn, Evelyn, Elwing, Jean M., Moss, John E., Eggert, Michael, Shlobin, Oksana A., P. Frantz, Robert, D. Bartolome, Sonja, Mathai, Stephen C., Mazimba, Sula, C. Pugliese, Steven, Al-Naamani, Nadine

“…Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, morbid, potentially curable subtype of pulmonary hypertension that negatively impacts…”
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Anticoagulation in Pulmonary Arterial Hypertension by Robinson, Jeffrey C., Pugliese, Steven C., Fox, Daniel L., Badesch, David B.

“…Pulmonary arterial hypertension (PAH) is characterized by molecular and pathologic alteration to the pulmonary circulation, resulting in increased pulmonary…”
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Secular and Regional Trends among Pulmonary Arterial Hypertension Clinical Trial Participants by Min, Jeff, Appleby, Dina H, McClelland, Robyn L, Minhas, Jasleen, Holmes, John H, Urbanowicz, Ryan J, Pugliese, Steven C, Mazurek, Jeremy A, Smith, K Akaya, Fritz, Jason S, Palevsky, Harold I, Suh, Jude Moutchia, Al-Naamani, Nadine, Kawut, Steven M

“…The population of patients with pulmonary arterial hypertension (PAH) has evolved over time from predominantly young White women to an older, more racially…”
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Systemic arterial properties in pulmonary hypertension by Goodman, Randi, Chirinos, Julio A., Ky, Bonnie, Mazurek, Jeremy A., Smith, Kerri Akaya, Palevsky, Harold I., Fritz, Jason S., Pugliese, Steven C., Kawut, Steven M., Al-Naamani, Nadine

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Clinical use of extended-release oral treprostinil in the treatment of pulmonary arterial hypertension by Pugliese, Steven C, Bull, Todd M

“…The development of parenteral prostacyclin therapy marked a dramatic breakthrough in the treatment of pulmonary arterial hypertension (PAH). Intravenous (IV)…”
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Abstract 16338: Outcomes in Patients With High-Risk Pulmonary Embolism Undergoing Extracorporeal Membrane Oxygenation and Adjunctive Treatment Strategy, Including Percutaneous and Surgical Management- A Retrospective Study at a Tertiary Care Center by Park, Joseph H, Schurr, James W, Pugliese, Steven

“…Abstract only Introduction: The management of high-risk PE has remained challenging with high mortality rates. Several first-line treatments have been…”
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