Search Results - "Pugh, George"

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    Steviol glycosides in purified stevia leaf extract sharing the same metabolic fate by Purkayastha, Sidd, Markosyan, Avetik, Prakash, Indra, Bhusari, Sachin, Pugh, George, Lynch, Barry, Roberts, Ashley

    Published in Regulatory toxicology and pharmacology (01-06-2016)
    “…The safety of steviol glycosides is based on data available on several individual steviol glycosides and on the terminal absorbed metabolite, steviol. Many…”
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    In vitro metabolism of rebaudioside B, D, and M under anaerobic conditions: Comparison with rebaudioside A by Purkayastha, Sidd, Pugh, George, Lynch, Barry, Roberts, Ashley, Kwok, David, Tarka, Stanley M.

    Published in Regulatory toxicology and pharmacology (01-03-2014)
    “…•Anaerobic metabolism of rebaudiosides A, B, D, and M was evaluated.•Pooled human fecal homogenates from males and females used as source of…”
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    Chemical-specific adjustment factors (inter-species toxicokinetics) to establish the ADI for steviol glycosides by Roberts, Ashley, Lynch, Barry, Rogerson, Rebecca, Renwick, Andrew, Kern, Hua, Coffee, Matthew, Cuellar-Kingston, Nicole, Eapen, Alex, Crincoli, Christine, Pugh, George, Bhusari, Sachin, Purkayastha, Sidd, Carakostas, Michael

    Published in Regulatory toxicology and pharmacology (01-08-2016)
    “…The acceptable daily intake (ADI) of commercially available steviol glycosides is currently 0–4 mg/kg body weight (bw)/day, based on application of a 100-fold…”
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    In vitro metabolism of rebaudioside E under anaerobic conditions: Comparison with rebaudioside A by Purkayastha, Sidd, Bhusari, Sachin, Pugh, George, Teng, Xiaowei, Kwok, David, Tarka, Stanley M.

    Published in Regulatory toxicology and pharmacology (01-08-2015)
    “…The hydrolysis of the steviol glycosides rebaudioside (Reb) A and E, as well as steviolbioside (a metabolic intermediate) to steviol was evaluated in vitro…”
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    Evaluation of Side Effects and Patients' Perceptions during Tooth Bleaching by LEONARD JR, RALPH H., SMITH, LYNN R., GARLAND, GLENN E., TIWANA, KAREN K., ZAIDEL, LYNETTE A., PUGH JR, GEORGE, LIN, NORA C.

    “…ABSTRACT Objective:  The objective of this nightguard vital bleaching (NGVB) study was to compare tooth sensitivity (TS), gingival irritation (GIr), and other…”
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    COMPARATIVE EFFECTS OF PHTHALATE MONOESTERS ON GAP JUNCTIONAL INTERCELLULAR COMMUNICATION AND PEROXISOME PROLIFERATION IN RODENT AND PRIMATE HEPATOCYTES by Kamendulis, Lisa M., Isenberg, Jason S., Smith, Jacqueline H., Jr, George Pugh, Lington, Arthur W., Klaunig, James E.

    “…Several phthalate esters, compounds used as plasticizers in a variety of commercial products, have been shown to induce hepatic tumors in rodents. In this…”
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    High Levels of Hydrogen Peroxide in Overnight Tooth‐Whitening Formulas: Effects on Enamel and Pulp by Jr, GEORGE PUGH, ZAIDEL, LYNETTE, LIN, NORA, STRANICK, MICHAEL, BAGLEY, DANIEL

    “…ABSTRACT Purpose:: Limited data are available to assess the safety of high levels of hydrogen peroxide in overnight tooth‐whitening formulas. The purpose of…”
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    Involvement of dynorphin B in the antinociceptive effects of the cannabinoid CP55,940 in the spinal cord by Pugh, Jr, G, Mason, Jr, D J, Combs, V, Welch, S P

    “…Intrathecal administration of delta 9-tetrahydrocannabinol (delta 9-THC) but not the cannabinoid agonist CP55,940 enhances the antinociception produced by…”
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    Reversibility and persistence of di-2-ethylhexyl phthalate (DEHP)- and phenobarbital-induced hepatocellular changes in rodents by ISENBERG, Jason S, KAMENDULIS, Lisa M, ACKLEY, David C, SMITH, Jacqueline H, PUGH, George JR, LINGTON, Arthur W, MCKEE, Richard H, KLAUNIG, James E

    Published in Toxicological sciences (01-12-2001)
    “…The tumor promotion stage of chemical carcinogenesis has been shown to exhibit a persistence of cellular effects during treatment and the reversibility of…”
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    The potential developmental neurotoxicity of calcium cyclamate in CD rats by Roberts, Ashley, Renwick, Andrew G., Stannard, Diane, Myers, David, Pugh, George, Bhusari, Sachin

    Published in Food and chemical toxicology (01-07-2021)
    “…The developmental neurotoxicity of calcium cyclamate was evaluated in Sprague Dawley [Crl:CD(SD)] rats, administered in drinking water, in comparison to a…”
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    Comparative In vitro metabolism of purified mogrosides derived from monk fruit extracts by Bhusari, Sachin, Rodriguez, Chester, Tarka, Stanley M., Kwok, David, Pugh, George, Gujral, Jaspreet, Tonucci, David

    Published in Regulatory toxicology and pharmacology (01-03-2021)
    “…Mogrosides are the primary components responsible for the sweet taste of Monk fruit which is derived from Siraitia grosvenorii (Swingle), a herbaceous plant…”
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    Powerful proposals: How to give your business the winning edge by Pugh, David G, Bacon, Terry R

    Published 2005
    “…"Powerful Proposals" gives businesses proven strategies for creating customer-centered documents that outshine the competition every time. "Powerful Proposals"…”
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    The behavioral advantage: What the Smartest, Most Successful Companies Do Differently to Win in the B2B Arena by Bacon, Terry R, Pugh, David G

    Published 2004
    “…The "Behavioral Advantage" reveals the secrets behind what is essentially a chess game with competitors. To win the game, companies must develop: a carefully…”
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    Theory of Measures of Effectiveness for General-Purpose Military Forces: Part II. Lagrange Dynamic Programming in Time-Sequential Combat Games by Pugh, George E

    Published in Operations research (01-07-1973)
    “…This paper develops a method for converting the overall objectives of a military campaign into specific time-dependent objectives, suitable for guiding…”
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    Effects of di-isononyl phthalate, di-2-ethylhexyl phthalate, and clofibrate in cynomolgus monkeys by PUGH, G. JR, ISENBERG, J. S, KAMENDULIS, L. M, ACKLEY, D. C, CLARE, L. J, BROWN, R, LINGTON, A. W, SMITH, J. H, KLAUNIG, J. E

    Published in Toxicological sciences (01-07-2000)
    “…The effects of the peroxisome proliferators di-isononyl phthalate (DINP) and di-2-ethylhexyl phthalate (DEHP) were evaluated in young adult male cynomolgus…”
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