Search Results - "Puertas, R."

Imaging mass spectrometry (IMS) of cortical lipids from preclinical to severe stages of Alzheimer's disease by Gónzalez de San Román, E., Manuel, I., Giralt, M.T., Ferrer, I., Rodríguez-Puertas, R.

“…Alzheimer's disease (AD) is a progressive neurodegenerative disease affecting millions of patients worldwide. Previous studies have demonstrated alterations in…”
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Neuroanatomical characterization of the G protein-coupled receptor activity evoked by galanin-related ligands by Barreda-Gómez, G., Manuel, I., Rodríguez-Puertas, R.

“…Galanin neuropeptide is distributed throughout the mammalian nervous system modulating a plethora of diverse physiological functions, including nociception,…”
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Lipid mapping of the rat brain for models of disease by Martínez-Gardeazabal, J, González de San Román, E, Moreno-Rodríguez, M, Llorente-Ovejero, A, Manuel, I, Rodríguez-Puertas, R

“…Lipids not only constitute the primary component of cellular membranes and contribute to metabolism but also serve as intracellular signaling molecules and…”
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Matrix-assisted laser desorption ionization imaging mass spectrometry in lipidomics by Fernández, J. A., Ochoa, B., Fresnedo, O., Giralt, M. T., Rodríguez-Puertas, R.

“…The relevant structural, energetics, and regulatory roles of lipids are universally acknowledged. However, the high variability of lipid species and the large…”
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Analysis of the nexus between country risk, environmental policies, and human development by Martí, L., Cervelló-Royo, R., Puertas, R.

“…There is currently a two-way link between financial risk and climate change. International agreements on climate change involve more sustainable practices…”
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Atrial fibrillation is associated with hypermethylation in human left atrium, and treatment with decitabine reduces atrial tachyarrhythmias in spontaneously hypertensive rats by Doñate Puertas, R, Meugnier, E, Romestaing, C, Rey, C, Morel, E, Lachuer, J, Gadot, N, Scridon, A, Julien, C, Tronc, F, Chapuis, B, Valla, C, Janin, A, Pirola, L, Méjat, A, Rome, S, Chevalier, P

“…Atrial fibrillation (AF) is the most common cardiac arrhythmia. As the molecular mechanisms underlying the pathology are largely unknown, this cardiac…”
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Effects of galanin subchronic treatment on memory and muscarinic receptors by Barreda-Gómez, G, Lombardero, L, Giralt, M.T, Manuel, I, Rodríguez-Puertas, R

“…Graphical abstract…”
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Delta‐like protein 1 in the pituitary‐adipose axis in the adult male mouse by Bello, A. R., Puertas‐Avendaño, R. A., González‐Gómez, M. J., González‐Gómez, M., Laborda, J., Damas, C., Ruiz‐Hidalgo, M., Diaz, C.

“…With the aim of studying delta‐like protein 1 (DLK1) with respect to the relationship between adipocyte leptin and adenohypophyseal hormones, we carried out…”
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Plitidepsin as a successful rescue treatment for prolonged viral SARS-CoV-2 replication in a patient with previous anti-CD20 monoclonal antibody-mediated B cell depletion and chronic lymphocytic leukemia by Guisado-Vasco, P, Carralón-González, M M, Aguareles-Gorines, J, Martí-Ballesteros, E M, Sánchez-Manzano, M D, Carnevali-Ruiz, D, García-Coca, M, Barrena-Puertas, R, de Viedma, R García, Luque-Pinilla, J M, Sotres-Fernandez, G, Fernández-Sousa, J M, Luepke-Estefan, X E, López-Martín, J A, Jimeno, J M

“…There is an urgent need for highly efficacious antiviral therapies in immunosuppressed hosts who develop coronavirus disease (COVID-19), with special concern…”
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Role of the Non-Canonical Notch Ligand Delta-Like Protein 1 in Hormone-Producing Cells of the Adult Male Mouse Pituitary by Puertas-Avendaño, R. A., González-Gómez, M. J., Ruvira, M. D., Ruiz-Hidalgo, M. J., Morales-Delgado, N., Laborda, J., Díaz, C., Bello, A. R.

“…To better understand the role of the non‐canonical Notch ligand delta‐like protein 1 (DLK1), in hormone‐producing cells, we studied the cell distribution and…”
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Galanin activated Gi/o -proteins in human and rat central nervous systems by Barreda-Gómez, G, Giralt, M.T, Pazos, A, Rodríguez-Puertas, R

“…Highlights • The [35 S]GTPγS autoradiography activated by GAL shows the distribution of functional GALR in postmortem human brain. • The activity mediated by…”
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International ranking of climate change action: An analysis using the indicators from the Climate Change Performance Index by Puertas, R., Marti, L.

“…It is hard to argue against the reality of global warming, its consequences are becoming increasingly evident not only due to the effects of extreme weather…”
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Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of α2A-adrenoceptors by GONZALEZ-MAESO, J, RODRIGUEZ-PUENAS, R, MEANA, J. J, GARCIA-SEVILLA, J. A, GUIMON, J

“…Abnormalities in the density of neuroreceptors that regulate norepinephrine and serotonin release have been repeatedly reported in brains of suicide victims…”
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Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of alpha(2A)-adrenoceptors by González-Maeso, J, Rodríguez-Puertas, R, Meana, J J, García-Sevilla, J A, Guimón, J

“…Abnormalities in the density of neuroreceptors that regulate norepinephrine and serotonin release have been repeatedly reported in brains of suicide victims…”
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G protein-coupled galanin receptor distribution in the rat central nervous system by Barreda-Gómez, G., Giralt, M.T., Rodríguez-Puertas, R.

“…The action of galanin in the central nervous system is mediated by at least three galanin receptor subtypes (GalR1, GalR2 and GalR3) which belong to the family…”
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Autoradiography of receptor-activated G-proteins in post mortem human brain by Rodrı́guez-Puertas, R., González-Maeso, J., Meana, J.J., Pazos, A.

“…The agonist-stimulated guanosine 5′-(γ-[ 35S]thio)triphosphate binding assay was used to anatomically localize receptor-activated G-proteins by autoradiography…”
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Solid phases in cycloheptanol: Dynamic disorder and glass transitions by Salud, J., López, D.O., Diez-Berart, S., Pérez-Jubindo, M.A., de la Fuente, M.R., Rute, M.A., Puertas, R.

“…The stable solid polymorphism of cycloheptanol (C 7H 14O, for short C 7–OH) is revised in the present paper. Four solid stable phases, denoted on cooling from…”
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Static and dynamic studies on cycloheptanol as two-orientational glass-former by Puertas, R., Salud, J., López, D.O., Rute, M.A., Diez, S., Tamarit, J.Ll, Barrio, M., Pérez-Jubindo, M.A., de la Fuente, M.R., Pardo, L.C.

“…Two-orientational glass transitions of two different orientationally disordered states of cycloheptanol are investigated and compared through static…”
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Effects of central galanin administration on muscarinic cholinergic and galanin receptor G protein coupling by Barreda-Gómez, G., Giralt, M.T., Rodrı́guez-Puertas, R.

“…The neuropeptide galanin is expressed in the mammalian central nervous system and has been implicated in neurotrophic actions. Central galanin administration…”
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Cannabinoid applications in glaucoma by Pinar-Sueiro, S, Rodríguez-Puertas, R, Vecino, E

“…Abstract Introduction Glaucoma is a slowly progressive optic neuropathy that is one of the leading causes of legal blindness throughout the world. Currently…”
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