Search Results - "Puehringer, Dirk"
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Reversible Membrane Interaction of BAD Requires two C-terminal Lipid Binding Domains in Conjunction with 14-3-3 Protein Binding
Published in The Journal of biological chemistry (23-06-2006)“…BAD is a Bcl-2 homology domain 3 (BH3)-only proapoptotic member of the Bcl-2 protein family that is regulated by phosphorylation in response to survival…”
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EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons
Published in Nature neuroscience (01-04-2013)“…In this study, the authors show that, in newborn cortical neurons, the TrkB and TrkC receptors are transactivated by the EGF receptor, rather than by their…”
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Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment
Published in Nature communications (20-07-2023)“…Immune checkpoint blockade therapy is beneficial and even curative for some cancer patients. However, the majority don’t respond to immune therapy. Across…”
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Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy
Published in Acta neuropathologica (01-09-2015)“…Diabetic neuropathy (DNP), afflicting sensory and motor nerve fibers, is a major complication in diabetes. The underlying cellular mechanisms of axon…”
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Differential modulation of neurite growth by the S- and the L-forms of bag1, a co-chaperone of Hsp70
Published in Neuro-degenerative diseases (01-01-2007)“…Bag1 acts as a cochaperone for Hsp70. However, it also binds to members of the RAF family and to Akt. In addition, bag1 and Hsp70 are part of a complex with…”
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