Search Results - "Puech, A"

An innovative combination of cypropheptadine and prazosin for the treatment of alcohol use disorder: a double-blind, randomised, parallel-group, three-arm, multicentre, placebo-controlled phase 2 trial by Aubin, H.-J., Puech, A.

“…Introduction Animal studies have shown that the simultaneous blockade of α1b-noradrenergic receptors and 5HT2A-serotonergic receptors strongly decreases…”
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Persistent Organic Pollutants in albacore tuna (Thunnus alalunga) from Reunion Island (Southwest Indian Ocean) and South Africa in relation to biological and trophic characteristics by Munschy, C., Bodin, N., Potier, M., Héas-Moisan, K., Pollono, C., Degroote, M., West, W., Hollanda, S.J., Puech, A., Bourjea, J., Nikolic, N.

“…The contamination of albacore tuna (Thunnus alalunga) by Persistent Organic Pollutants (POPs), namely polychlorinated biphenyls (PCBs) and…”
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Serotonin and tolerance to delay of reward in rats by Bizot, J, Le Bihan, C, Puech, A J, Hamon, M, Thiébot, M

“…Tolerance to delay of gratification, taken to reflect impulsiveness, has been proposed to be under the preferential control of central serotonin (5-HT)…”
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Effect of itraconazole on the pharmacokinetics of prednisolone and methylprednisolone and cortisol secretion in healthy subjects by Lebrun‐Vignes, B., Archer, V. Corbrion, Diquet, B., Levron, J. C., Chosidow, O., Puech, A. J., Warot, D.

“…Aims  Itraconazole is a potent inhibitor of CYP3A4 activity and is often used in combination with corticosteroids. Since the latter are partly metabolized by…”
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Training-induced improvement in lipid oxidation in type 2 diabetes mellitus is related to alterations in muscle mitochondrial activity. Effect of endurance training in type 2 diabetes by Bordenave, S, Metz, L, Flavier, S, Lambert, K, Ghanassia, E, Dupuy, A.-M, Michel, F, Puech-Cathala, A.-M, Raynaud, E, Brun, J.-F, Mercier, J

“…Abstract Aim We investigated whether or not, in type 2 diabetic (T2D) patients, an individualized training effect on whole-body lipid oxidation would be…”
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Involvement of central cannabinoid (CB1) receptors in the establishment of place conditioning in rats by CHAPERON, F, SOUBRIE, P, PUECH, A. J, THIEBOT, M.-H

“…The involvement of cannabinoid processes in positive reinforcement was studied using an unbiased, one-compartment, conditioned place preference (CPP) procedure…”
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Benefits from mianserin augmentation of fluoxetine in patients with major depression non-responders to fluoxetine alone by FERRERI, M, LAVERGNE, F, BERLIN, I, PAYAN, C, PUECH, A. J

“…To assess, in depressed patients, the clinical benefit of mianserin augmentation of fluoxetine or the the benefit of switching treatment from fluoxetine to…”
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Amisulpride, an atypical antipsychotic, in the treatment of acute episodes of schizophrenia: a dose-ranging study vs. haloperidol by Puech, A., Fleurot, O., Rein, W.

“…This 4‐week, double‐blind, randomized study was undertaken to determine the dose‐response relationship of amisulpride in 319 patients with acute exacerbation…”
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Genetics of dark skin in mice by Fitch, Karen R, McGowan, Kelly A, van Raamsdonk, Catherine D, Fuchs, Helmut, Lee, Daekee, Puech, Anne, Hérault, Yann, Threadgill, David W, Hrabé de Angelis, Martin, Barsh, Gregory S

“…Chemical mutagenesis in the mouse is a powerful approach for phenotype-driven genetics, but questions remain about the efficiency with which new mutations…”
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Basal plasma leptin levels in healthy elderly males are related to physical fitness without impact on bone metabolism by MAIMOUN, L, SIMAR, D, CAILLAUD, C, COSTE, O, PUECH, A.-M, JAUSSENT, A, MARIANO-GOULART, D, SULTAN, C

“…Investigated the relationship between leptin levels or bone remodelling and physical fitness level in healthy elderly participants. Twenty women and 18 men…”
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Measures of anhedonia and hedonic responses to sucrose in depressive and schizophrenic patients in comparison with healthy subjects by Berlin, I, Givry-Steiner, L, Lecrubier, Y, Puech, A.J.

“…Anhedonia may be considered as a transnosological feature of depression and schizophrenia. The aim of the present study was to assess hedonic responses to…”
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Treatment of negative symptoms in schizophrenia with amisulpride by Boyer, P, Lecrubier, Y, Puech, A J, Dewailly, J, Aubin, F

“…The efficacy of low doses of certain neuroleptics in improving negative symptoms is still controversial. This study assessed the efficacy of amisulpride, a…”
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Amisulpride improves depressive symptoms in acute exacerbations of schizophrenia: comparison with haloperidol and risperidone by Peuskens, J, Möller, H.J, Puech, A

“…The Brief Psychiatric Rating Scale (BPRS) anxiety/depression subscore has been used to assess affective symptoms in three studies ( n=612) comparing…”
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A reversible monoamine oxidase A inhibitor (moclobemide) facilitates smoking cessation and abstinence in heavy, dependent smokers by Berlin, I, Saïd, S, Spreux-Varoquaux, O, Launay, J M, Olivares, R, Millet, V, Lecrubier, Y, Puech, A J

“…To assess the effectiveness of moclobemide on smoking cessation and abstinence in heavy, dependent smokers. There is a strong association between smoking and…”
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Monoamine oxidase A and B activities in heavy smokers by Berlin, Ivan, Said, Sophie, Spreux-Varoquaux, Odile, Olivares, Robert, Launay, Jean-Marie, Puech, Alain J.

“…There is a strong association between depression and smoking. Because monoamine oxidase (MAO) inhibition leads to antidepressant effect and in vitro studies…”
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Milnacipran, a new serotonin and noradrenaline reuptake inhibitor: an overview of its antidepressant activity and clinical tolerability by Puech, A, Montgomery, S A, Prost, J F, Solles, A, Briley, M

“…Milnacipran (Ixel) is a new antidepressant with essentially equal potency for inhibiting the reuptake of both serotonin and noradrenaline, with no affinity for…”
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Normal Cardiovascular Development in Mice Deficient for 16 Genes in 550 kb of the Velocardiofacial/DiGeorge Syndrome Region by Puech, A, Saint-Jore, B, Merscher, S, Russell, R G, Cherif, D, Sirotkin, H, Xu, H, Factor, S, Kucherlapati, R, Skoultchi, A I

“…Hemizygous interstitial deletions in human chromosome 22q11 are associated with velocardiofacial syndrome and DiGeorge syndrome and lead to multiple congenital…”
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Training and aging modulate the loss-of-balance phenotype observed in a new ENU-induced allele of Otopetrin1 by Besson, Vanessa, Nalesso, Valérie, Herpin, Alexandre, Bizot, Jean-Charles, Messaddeq, Nadia, Romand, Raymond, Puech, Anne, Blanquet, Véronique, Hérault, Yann

“…Background information. The sensing of head movement in mammals depends upon the vestibular endorgan of the inner ear, a complex structure made up of the…”
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A randomized double-blind placebo-controlled study of tropisetron in the treatment of outpatients with generalized anxiety disorder: 5-HT by LECRUBIER, Y, PUECH, A. J, AZCONA, A, BAILEY, P. E, LATASTE, X

“…The selective 5HT3 antagonist tropisetron was studied in 91 outpatients meeting DSM-III criteria for Generalized Anxiety Disorder. Following a placebo washout…”
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Animal behavioural studies in the evaluation of antidepressant drugs by Thiébot, M H, Martin, P, Puech, A J

“…Animal behavioural models of psychiatric disorders cannot exactly simulate human psychopathology, but they can be used to evaluate the behavioural changes…”
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