Search Results - "Pu, Zhijun"
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Curcumin: a calixarene derivative micelle potentiates anti-breast cancer stem cells effects in xenografted, triple-negative breast cancer mouse models
Published in Drug delivery (2017)“…Triple-negative breast cancer (TNBC) is a heterogeneous and clinically aggressive disease with no approved targeted therapy. Curcumin has shown therapeutic…”
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Regulation of Microglia-Activation-Mediated Neuroinflammation to Ameliorate Ischemia-Reperfusion Injury via the STAT5-NF-κB Pathway in Ischemic Stroke
Published in Brain sciences (29-08-2022)“…Inflammatory reaction after ischemia-reperfusion contributes significantly to a worsened prognosis, and microglia activation is the main resource of…”
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Synthetic VSMCs induce BBB disruption mediated by MYPT1 in ischemic stroke
Published in iScience (24-09-2021)“…Vascular smooth muscle cells (VSMCs) have been widely recognized as key players in regulating blood-brain barrier (BBB) function, and their roles are unclear…”
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Antioxidative and antiapoptosis: Neuroprotective effects of dauricine in Alzheimer's disease models
Published in Life sciences (1973) (15-02-2020)“…Dauricine has been found that has significant neuroprotective effect on Alzheimer's disease (AD), but the mechanism is unclear, so we further investigated the…”
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Amyloid-beta Degradation and Neuroprotection of Dauricine Mediated by Unfolded Protein Response in a Caenorhabditis elegans Model of Alzheimer’s disease
Published in Neuroscience (10-11-2018)“…•The pharmacodynamic value of dauricine on preventing and attenuating the progression of AD is confirmed.•Unfolded protein response played a key role during…”
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Lycopene attenuates Aβ1–42 secretion and its toxicity in human cell and Caenorhabditis elegans models of Alzheimer disease
Published in Neuroscience letters (03-11-2015)“…•Lycopene delayed the paralysis in the Aβ1–42-transgenic Caenorhabditis elegans strain GMC101.•Lycopene reduced Aβ1–42 secretion level in human SH-SY5Y…”
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Hypoxia-Induced Myocardial Hypertrophy Companies with Apoptosis Enhancement and p38-MAPK Pathway Activation
Published in High altitude medicine & biology (01-09-2024)“…Li, Xiaoxu, Zhijun Pu, Gang Xu, Yidong Yang, Yu Cui, Xiaoying Zhou, Chenyuan Wang, Zhifeng Zhong, Simin Zhou, Jun Yin, Fabo Shan, Chengzhong Yang, Li Jiao,…”
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Oxoisoaporphine alkaloid derivative 8-1 reduces Aβ1-42 secretion and toxicity in human cell and Caenorhabditis elegans models of Alzheimer's disease
Published in Neurochemistry international (01-09-2017)“…Alzheimer's disease (AD) is a multifactorial neurodegenerative disease and a growing health problem worldwide. Because the drugs currently used to treat AD…”
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Serpine1 Regulates Peripheral Neutrophil Recruitment and Acts as Potential Target in Ischemic Stroke
Published in Journal of inflammation research (30-04-2022)“…Peripheral neutrophil infiltration can exacerbate ischemia-reperfusion injury. We focused on the relationship between various peripheral immune cells and…”
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Application of Multimedia Technology in Male Aerobics Teaching of Physical Education Major
Published in 2021 International Symposium on Advances in Informatics, Electronics and Education (ISAIEE) (01-12-2021)“…Nowadays, sports are attracting more and more attention. Aerobics, which integrates gymnastics, dance and music, can well reflect the static and dynamic beauty…”
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Conference Proceeding -
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Oxoisoaporphine alkaloid derivative 8-1 reduces Aβ 1-42 secretion and toxicity in human cell and Caenorhabditis elegans models of Alzheimer's disease
Published in Neurochemistry international (01-09-2017)“…Alzheimer's disease (AD) is a multifactorial neurodegenerative disease and a growing health problem worldwide. Because the drugs currently used to treat AD…”
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Journal Article