Search Results - "Psyrri, A"

The mutational spectrum of squamous-cell carcinoma of the head and neck: targetable genetic events and clinical impact by Mountzios, G., Rampias, T., Psyrri, A.

“…Squamous-cell cancer of the head and neck (SCCHN) represents a heterogeneous disease entity, with various etiological factors implicated in the genesis of…”
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Beyond BRCA : New hereditary breast cancer susceptibility genes by Economopoulou, P, Dimitriadis, G, Psyrri, A

“…Highlights • Sequencing of specific genes can identify families at risk of breast cancer. • Multigene panel testing should be performed after consultation with…”
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The promise of immunotherapy in head and neck squamous cell carcinoma by Economopoulou, P., Agelaki, S., Perisanidis, C., Giotakis, E.I., Psyrri, A.

“…Squamous cell cancers of the head and neck (HNSCC) comprise a diverse group of malignancies that includes tobacco-related tumors in addition to an increasing…”
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The current and future impact of human papillomavirus on treatment of squamous cell carcinoma of the head and neck by Psyrri, A., Rampias, T., Vermorken, J.B.

“…Squamous cell carcinoma of the head and neck (SCCHN) was traditionally associated with smoking and alcohol use; however, human papillomavirus (HPV) infection…”
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Primary extranodal lymphomas of stomach: clinical presentation, diagnostic pitfalls and management by Psyrri, A., Papageorgiou, S., Economopoulos, T.

“…Gastrointestinal lymphoma is the most common form of extranodal lymphoma, accounting for 30%–40% of cases. The most commonly involved site is the stomach…”
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Epstein–Barr virus DNA detection by targeted sequencing in post-treatment plasma samples and prognosis of locally advanced nasopharyngeal cancer: implications for clinical research by Economopoulou, P., Lianidou, E., Psyrri, A.

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Prognostic significance of PD-L1 expression on circulating tumor cells in patients with head and neck squamous cell carcinoma by Strati, A., Koutsodontis, G., Papaxoinis, G., Angelidis, I., Zavridou, M., Economopoulou, P., Kotsantis, I., Avgeris, M., Mazel, M., Perisanidis, C., Sasaki, C., Alix-Panabières, C., Lianidou, E., Psyrri, A.

“…Successful application of programmed death 1 (PD1) checkpoint inhibitors in the clinic may ultimately benefit from appropriate patient selection based upon…”
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Liquid biopsy: An emerging prognostic and predictive tool in Head and Neck Squamous Cell Carcinoma (HNSCC). Focus on Circulating Tumor Cells (CTCs) by Economopoulou, P., Kotsantis, I., Kyrodimos, E., Lianidou, E.S., Psyrri, A.

“…•Liquid biopsy refers to analysis of circulating genetic material in the blood.•CTCs and ctDNA are detectable in head and neck cancer.•CTCs have been found to…”
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RAS/PI3K Crosstalk and Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma by RAMPIAS, T, GIAGINI, A, SIOLOS, S, MATSUZAKI, H, SASAKI, C, SCORILAS, A, PSYRRI, A

“…Cetuximab, an antibody directed against the EGF receptor, is an effective clinical therapy for patients with head and neck squamous cell cancer (HNSCC)…”
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Impact of tumor HPV status on outcome in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck receiving chemotherapy with or without cetuximab: retrospective analysis of the phase III EXTREME trial by Vermorken, J.B., Psyrri, A., Mesía, R., Peyrade, F., Beier, F., de Blas, B., Celik, I., Licitra, L.

“…Tumor human papillomavirus (HPV) status is an important prognostic factor in locoregionally advanced squamous cell carcinoma of the head and neck (SCCHN)…”
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Durvalumab with or without tremelimumab versus the EXTREME regimen as first-line treatment for recurrent or metastatic squamous cell carcinoma of the head and neck: KESTREL, a randomized, open-label, phase III study by Psyrri, A., Fayette, J., Harrington, K., Gillison, M., Ahn, M.-J., Takahashi, S., Weiss, J., Machiels, J.-P., Baxi, S., Vasilyev, A., Karpenko, A., Dvorkin, M., Hsieh, C.-Y., Thungappa, S.C., Segura, P.P., Vynnychenko, I., Haddad, R., Kasper, S., Mauz, P.-S., Baker, V., He, P., Evans, B., Wildsmith, S., Olsson, R.F., Yovine, A., Kurland, J.F., Morsli, N., Seiwert, T.Y.

“…Patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) have a poor prognosis. The phase III KESTREL study evaluated the…”
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Prognostic role of pretreatment plasma fibrinogen in patients with solid tumors: A systematic review and meta-analysis by Perisanidis, C, Psyrri, A, Cohen, E.E, Engelmann, J, Heinze, G, Perisanidis, B, Stift, A, Filipits, M, Kornek, G, Nkenke, E

“…Highlights • The prognostic value of baseline plasma fibrinogen in solid tumors was assessed. • High fibrinogen is associated with poor prognosis of patients…”
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E6 and E7 Gene Silencing and Transformed Phenotype of Human Papillomavirus 16–Positive Oropharyngeal Cancer Cells by Rampias, Theodore, Sasaki, Clarence, Weinberger, Paul, Psyrri, Amanda

“…Background The E6 and E7 genes of human papillomavirus type 16 (HPV16) encode oncoproteins that bind and degrade p53 and retinoblastoma (pRb) tumor…”
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The prognostic significance of p16 overexpression in oropharyngeal squamous cell carcinoma: implications for treatment strategies and future clinical studies by Langendijk, J.A., Psyrri, A.

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Granulosa cell tumor of the ovary by Pectasides, D, Pectasides, E, Psyrri, A

“…Summary Ovarian granulosa cell tumors (GCTs) are uncommon neoplasms that arise from the sex-cord stromal cells of the ovary. GCTs are characterized by long…”
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KEYNOTE-048: Phase III study of first-line pembrolizumab (P) for recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) by Burtness, B., Harrington, K.J., Greil, R., Soulières, D., Tahara, M., De Castro, G., Psyrri, A., Baste Rotllan, N., Neupane, P.C., Bratland, Å, Fuereder, T., Hughes, B.G.M., Mesia, R., Ngamphaiboon, N., Rordorf, T., Wan Ishak, W.Z., Roy, A., Cheng, J., Jin, F., Rischin, D.

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B-cell infiltration is associated with survival outcomes following programmed cell death protein 1 inhibition in head and neck squamous cell carcinoma by Gavrielatou, N, Fortis, E, Spathis, A, Anastasiou, M, Economopoulou, P, Foukas, G R P, Lelegiannis, I M, Rusakiewicz, S, Vathiotis, I, Aung, T N, Tissot, S, Kastrinou, A, Kotsantis, I, Vagia, E M, Panayiotides, I, Rimm, D L, Coukos, G, Homicsko, K, Foukas, P, Psyrri, A

“…Programmed cell death protein 1 (PD-1) axis blockade has become the mainstay in the treatment of recurrent and/or metastatic (R/M) head and neck squamous cell…”
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Pathologic complete response in patients with localized soft tissue sarcoma treated with neoadjuvant therapy and its correlation with clinical outcomes: A systematic review by Boulouta, A., Kyriazoglou, A., Kotsantis, I., Economopoulou, P., Anastasiou, M., Pantazopoulos, A., Kyrkasiadou, M., Moutafi, M., Gavrielatou, N., Zazas, E., Caglar, C., Nixon, I., Tolia, M., Kavourakis, G., Psyrri, A.

“…•The choice of perioperative treatment for soft tissue sarcomas (STS) remains a challenging decision.•There is a shift towards neoadjuvant therapy due to…”
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Well-differentiated liposarcomas and dedifferentiated liposarcomas: Systemic treatment options for two sibling neoplasms by Kyriazoglou, A., Pagkali, A., Kotsantis, I., Economopoulou, P., Kyrkasiadou, M., Moutafi, M., Gavrielatou, N., Anastasiou, M., Boulouta, A., Pantazopoulos, A., Giannakakou, M., Digklia, A., Psyrri, A.

“…•Anthracyclines remain the gold standard in first-line treatment challenged by molecular targets as mdm2 inhibitors.•PFS and OS endpoints have not been…”
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Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A Hellenic Cooperative Oncology Group (HeCOG) Study by Psyrri, A., Kalogeras, K.T., Kronenwett, R., Wirtz, R.M., Batistatou, A., Bournakis, E., Timotheadou, E., Gogas, H., Aravantinos, G., Christodoulou, C., Makatsoris, T., Linardou, H., Pectasides, D., Pavlidis, N., Economopoulos, T., Fountzilas, G.

“…The ubiquitin–proteasome system (UPS) plays a pivotal role in tumorigenesis. Components of the UPS have recently been implicated in breast cancer progression…”
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