Search Results - "Przybyszewski, Waldemar"
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Ionizing radiation-induced bystander effects, potential targets for modulation of radiotherapy
Published in European journal of pharmacology (25-12-2009)“…Cells exposed to ionizing radiation show DNA damage, apoptosis, chromosomal aberrations or increased mutation frequency and for a long time it was generally…”
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Oxidative stress in prostate hypertrophy and carcinogenesis
Published in Postȩpy higieny i medycyny doświadczalnej (20-07-2009)“…Aging, significant impairment of the oxidation/reduction balance, infection, and inflammation are recognized risk factors of benign hyperplasia and prostate…”
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Dose rate-dependent cellular and molecular effects of ionizing radiation
Published in Postȩpy higieny i medycyny doświadczalnej (11-09-2008)“…The aim of radiation therapy is to kill tumor cells while minimizing damage to normal cells. The ultimate effect of radiation can be apoptotic or necrotic cell…”
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Multiple bystander effect of irradiated megacolonies of melanoma cells on non-irradiated neighbours
Published in Cancer letters (08-10-2004)“…The multicellular megacolonies of human melanoma Me45 line growing on one part of the bottom of culture flasks were irradiated with 5 Gy (60Co), whereas…”
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Bystander normal human fibroblasts reduce damage response in radiation targeted cancer cells through intercellular ROS level modulation
Published in Mutation research (01-03-2012)“…The radiation-induced bystander effect is a well-established phenomenon which results in damage in non-irradiated cells in response to signaling from…”
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Protective effect of local temporary ischemia depends on applied dose of radiation
Published in Cancer letters (10-05-2005)“…The aim of this study was to verify hypothesis that protective effect of local temporary ischemia depends on dose of radiation. 56 male WAG-strain rats were…”
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Investigation of metabolic changes in irradiated rat brain tissue by means of 1H NMR in vitro relaxation study
Published in Solid state nuclear magnetic resonance (2004)“…The effect of irradiation on concentrations and relaxation behaviour of brain metabolites was studied by means of high-resolution 1H NMR in vitro. The studies…”
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PEROXIDATIVE CHANGES IN RAT MYOCARDIUM PRODUCED BY GAMMA RAYS OR FARMORUBICIN: PREVENTION BY CARDIOXANE OR NEOTON
Published in Toxic substance mechanisms (01-01-1998)“…This investigation reports a lack of antioxidant capacity of drugs used as cardioprotectors, Cardioxane and Neoton, to prevent peroxidative heart damage…”
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FAILURE OF CARDIOXANE (ICRF-187, DEXRAZOXANE) TO LIMIT PEROXIDATIVE HEART DAMAGE IN RATS AFTER GAMMA IRRADIATION OR FARMORUBICIN (48-EPIDOXORUBICIN) TREATMENT
Published in Toxic substance mechanisms (01-04-1997)“…The ability of Cardioxane to protect against the peroxidative type of heart damage induced by a single treatm ent with farmorubicin (10 mg/ kg ip) or ionizing…”
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Lipid peroxidation, DNA damage, and cellular morphology of R1 Rhabdomyosarcoma cell line irradiated in vitro by gamma-rays with different dose rates
Published in Teratogenesis, carcinogenesis, and mutagenesis (2002)“…The study examines the relationship between lipid peroxidation, DNA damage, and cell morphology after the exposure of R1 Rhabdomyosarcoma cells to two…”
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High resolution proton nuclear magnetic resonance (1H NMR) spectroscopy of surviving C6 glioma cells after X-ray irradiation
Published in Folia neuropathologica (2013)“…To study biochemical response of living model of glioma to X-rays irradiation using high resolution proton nuclear magnetic resonance (1H NMR) spectroscopy…”
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Radiation-induced bystander effect: the important part of ionizing radiation response. Potential clinical implications
Published in Postȩpy higieny i medycyny doświadczalnej (18-08-2009)“…It has long been a central radiobiological dogma that the damaging effects of ionizing radiation, such as cell death, cytogenetic changes, apoptosis,…”
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Inhibitory effect of local ischaemic preconditioning in total body irradiated rats
Published in Teratogenesis, carcinogenesis, and mutagenesis (2003)“…The aim of this study was to explore the relationship between local ischaemic preconditioning and the effectiveness of fractionated radiotherapy. The rat…”
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Radical mechanism of hydroxyurea side toxicity
Published in Postȩpy higieny i medycyny doświadczalnej (2006)“…It has been shown that hydroxyurea (HU) induces free radicals which exert cytotoxic effects on cells. However, the molecular mechanism of this effect is still…”
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Regulation of intracellular processes by fatty acids and end products of lipid peroxidation
Published in Postȩpy higieny i medycyny doświadczalnej (2002)“…Products of ingested fat metabolism and also products of lipid peroxidation influenced on genes expression being natural ligands for nuclear receptors…”
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Fatty acids as a potentially helpful supplement in cancer therapy
Published in Postȩpy higieny i medycyny doświadczalnej (2002)“…This review presents pro- and anticancer effects of fatty acids in vitro and in vivo. The epidemiological and experimental data indicate that short-chain…”
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Cardiotoxic consequences of ionizing radiation and anthracyclines
Published in Postȩpy higieny i medycyny doświadczalnej (2006)“…The mechanisms of the toxic side effects of radiation and anthracyclines are generally based on free radical reactions. Target molecules for free radicals are…”
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Influence of local peripheral temporary ischaemia on biochemical and histological effects in small intestine and serum of rats following abdominal irradiation
Published in Folia biologica (01-01-2008)“…The local temporary ischaemia effect on radiation-induced lipid peroxidation, superoxide dismutase isoenzyme activities, and intestinal crypt number was…”
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