Search Results - "Przybyło, Małgorzata"

Altered Glycosylation in Progression and Management of Bladder Cancer by Wilczak, Magdalena, Surman, Magdalena, Przybyło, Małgorzata

“…Bladder cancer (BC) is the 10th most common malignancy worldwide, with an estimated 573,000 new cases and 213,000 deaths in 2020. Available therapeutic…”
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Lectin-Based Study Reveals the Presence of Disease-Relevant Glycoepitopes in Bladder Cancer Cells and Ectosomes by Surman, Magdalena, Wilczak, Magdalena, Przybyło, Małgorzata

“…Bladder cancer is a malignancy that remains a therapeutic challenge and requires the identification of new biomarkers and mechanisms of progression. Several…”
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Extracellular Vesicles as Drug Delivery Systems - Methods of Production and Potential Therapeutic Applications by Surman, Magdalena, Drożdż, Anna, Stępień, Ewa, Przybyło, Małgorzata

“…Drug delivery systems are created to achieve the desired therapeutic effect of a specific pharmaceutical compound. Numerous drawbacks and side effects such as…”
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Shotgun proteomics of thyroid carcinoma exosomes – Insight into the role of exosomal proteins in carcinogenesis and thyroid homeostasis by Surman, Magdalena, Wilczak, Magdalena, Jankowska, Urszula, Skupień-Rabian, Bożena, Przybyło, Małgorzata

“…Transport of molecules via exosomes is one of the factors involved in thyroid cancer development, and transported molecules may serve as cancer biomarkers. The…”
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Similarities and Differences in the Protein Composition of Cutaneous Melanoma Cells and Their Exosomes Identified by Mass Spectrometry by Surman, Magdalena, Jankowska, Urszula, Wilczak, Magdalena, Przybyło, Małgorzata

“…Intercellular transport of proteins mediated by extracellular vesicles (EVs)-exosomes and ectosomes-is one of the factors facilitating carcinogenesis…”
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Human melanoma-derived ectosomes are enriched with specific glycan epitopes by Surman, Magdalena, Hoja-Łukowicz, Dorota, Szwed, Sabina, Drożdż, Anna, Stępień, Ewa, Przybyło, Małgorzata

“…Numerous studies confirmed the involvement of extracellular vesicles in cancer development and progression. The present study was designed to investigate the…”
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Proteomic Profiling of Ectosomes Derived from Paired Urothelial Bladder Cancer and Normal Cells Reveals the Presence of Biologically-Relevant Molecules by Surman, Magdalena, Kędracka-Krok, Sylwia, Jankowska, Urszula, Drożdż, Anna, Stępień, Ewa, Przybyło, Małgorzata

“…Protein content of extracellular vesicles (EVs) can modulate different processes during carcinogenesis. Novel proteomic strategies have been applied several…”
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The Clinical Trial Landscape for Melanoma Therapies by Wróbel, Sonia, Przybyło, Małgorzata, Stępień, Ewa

“…(1) Despite many years of research, melanoma still remains a big challenge for modern medicine. The purpose of this article is to review publicly available…”
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Deciphering the role of ectosomes in cancer development and progression: focus on the proteome by Surman, Magdalena, Stępień, Ewa, Hoja-Łukowicz, Dorota, Przybyło, Małgorzata

“…Ectosomes are small heterogeneous membrane vesicles generated by budding from the plasma membrane in a variety of cell types and, more frequently, in tumor…”
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An Insight into the Proteome of Uveal Melanoma-Derived Ectosomes Reveals the Presence of Potentially Useful Biomarkers by Surman, Magdalena, Hoja-Łukowicz, Dorota, Szwed, Sabina, Kędracka-Krok, Sylwia, Jankowska, Urszula, Kurtyka, Magdalena, Drożdż, Anna, Lityńska, Anna, Stępień, Ewa, Przybyło, Małgorzata

“…Cancer cells are known to release extracellular vesicles that often promote disease development and progression. The present study investigated the protein…”
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The Proangiogenic Effects of Melanoma-Derived Ectosomes Are Mediated by αvβ5 Integrin Rather than αvβ3 Integrin by Surman, Magdalena, Wilczak, Magdalena, Bzowska, Małgorzata, Tylko, Grzegorz, Przybyło, Małgorzata

“…Ectosomes are carriers of proangiogenic factors during cancer progression. This study investigated whether the proangiogenic effect exerted by melanoma-derived…”
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On the trail of the glycan codes stored in cancer-related cell adhesion proteins by Hoja-Łukowicz, Dorota, Przybyło, Małgorzata, Duda, Małgorzata, Pocheć, Ewa, Bubka, Monika

“…Changes in the profile of protein glycosylation are a hallmark of ongoing neoplastic transformation. A unique set of tumor-associated carbohydrate antigens…”
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Mass Spectrometry-Based Proteomic Characterization of Cutaneous Melanoma Ectosomes Reveals the Presence of Cancer-Related Molecules by Surman, Magdalena, Kędracka-Krok, Sylwia, Hoja-Łukowicz, Dorota, Jankowska, Urszula, Drożdż, Anna, Stępień, Ewa Ł, Przybyło, Małgorzata

“…Cutaneous melanoma (CM) is an aggressive type of skin cancer for which effective biomarkers are still needed. Recently, the protein content of extracellular…”
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Melanoma-Derived Extracellular Vesicles: Focus on Their Proteome by Surman, Magdalena, Stępień, Ewa, Przybyło, Małgorzata

“…Malignant melanoma is one of the most aggressive types of cancer, and its incidence is increasing rapidly each year. Despite the extensive research into…”
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X-ray microtomography as a new approach for imaging and analysis of tumor spheroids by Karimi, Hanieh, Leszczyński, Bartosz, Kołodziej, Tomasz, Kubicz, Ewelina, Przybyło, Małgorzata, Stępień, Ewa

“…•3D spheroids visualization by micro-CT.•Two different cell lines: malignant (WM266-4) and primary (WM115) can form spheroids.•Micro-CT provides detailed…”
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Fourier-Transform InfraRed (FT-IR) spectroscopy to show alterations in molecular composition of EV subpopulations from melanoma cell lines in different malignancy by Stępień, Ewa Ł., Kamińska, Agnieszka, Surman, Magdalena, Karbowska, Dagmara, Wróbel, Andrzej, Przybyło, Małgorzata

“…Melanoma cells release extracellular vesicles (EVs) subpopulations which differ in size, phenotype and molecular content. Melanoma derived EVs play a role in…”
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Large extracellular vesicles do not mitigate the harmful effect of hyperglycemia on endothelial cell mobility by Drożdż, Anna, Kołodziej, Tomasz, Wróbel, Sonia, Misztal, Krzysztof, Targosz-Korecka, Marta, Drab, Marek, Jach, Robert, Rząca, Carina, Surman, Magdalena, Przybyło, Małgorzata, Rajfur, Zenon, Stępień, Ewa Ł.

“…Extracellular vesicles, especially the larger fraction (LEVs – large extracellular vesicles), are believed to be an important means of intercellular…”
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Towards understanding the role of sialylation in melanoma progression by Kolasińska, Ewa, Przybyło, Małgorzata, Janik, Marcelina, Lityńska, Anna

“…Aberrant expression of sialic acids or altered linkage types is closely associated with malignant phenotype and metastatic potential, and can have prognostic…”
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Comparative Proteomic Profiling of Ectosomes Derived from Thyroid Carcinoma and Normal Thyroid Cells Uncovers Multiple Proteins with Functional Implications in Cancer by Surman, Magdalena, Kędracka-Krok, Sylwia, Wilczak, Magdalena, Rybczyński, Piotr, Jankowska, Urszula, Przybyło, Małgorzata

“…Proteins carried by tumor-derived ectosomes play an important role in cancer progression, and are considered promising diagnostic markers. In the present…”
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Low-Vacuum Filtration as an Alternative Extracellular Vesicle Concentration Method: A Comparison with Ultracentrifugation and Differential Centrifugation by Drożdż, Anna, Kamińska, Agnieszka, Surman, Magdalena, Gonet-Surówka, Agnieszka, Jach, Robert, Huras, Hubert, Przybyło, Małgorzata, Stępień, Ewa Łucja

“…Recent years have brought great focus on the development of drug delivery systems based on extracellular vesicles (EVs). Considering the possible applications…”
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