Search Results - "Pryzdial, Ed L.G."

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    Persistence Of Dengue Virus In Stored Platelets and Red Blood Cells by Sutherland, Michael R, Simon, Ayo Y, Serrano, Katherine, Schubert, Peter, Acker, Jason, Pryzdial, Ed L.G.

    Published in Blood (15-11-2013)
    “…Dengue virus (DENV), a single stranded RNA member of the Flavivirus family, is responsible for morbidity and mortality, causes ∼50 million infections annually,…”
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    Journal Article
  3. 3

    Tissue Factor On The Herpes Simplex Virus Type 1 Surface Enhances Infection In Vivo by Sutherland, Michael R, Simon, Ayo Y, Shanina, Iryna, Horwitz, Marc S, Ruf, Wolfram, Pryzdial, Ed L.G.

    Published in Blood (15-11-2013)
    “…Tissue factor (TF) is a multifunctional transmembrane receptor. As the pivotal initiator of the coagulant response to vascular damage, it accelerates factor…”
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    Covalent Stabilization Of Coagulation Factor Xa Enhances Its Fibrinolytic Function In Vitro and In Vivo: A Novel Cofactor-Based Thrombolytic Agent by Pryzdial, Ed L.G., Talbot, Kimberley, Meixner, Scott C., Eltringham-Smith, Louise J., Sheffield, William P

    Published in Blood (15-11-2013)
    “…The key “clot-busting” enzyme, tissue plasminogen activator (tPA), functions to activate plasminogen (Pg) to plasmin, which directly cleaves and solubilizes…”
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    Journal Article
  5. 5

    Herpesviruses Enhance Fibrinogen Clot Lysis by Gershom, Edwin S, Hoek, Amanda Vanden, Sutherland, Michael R, Pryzdial, Ed L.G.

    Published in Blood (19-11-2010)
    “…Abstract 1153 Members of the Herpesvirus family have been implicated in vascular disease. To explain the correlation on a molecular basis we have shown that…”
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    Identification of a Novel Coagulation Factor X Compound Heterozygous Mutation Associated with Differential Initiating Clotting Pathway Function by Hoek, Amanda L Vanden, Talbot, Kimberley, Carter, Isis, Vickars, Linda, Carter, Cedric John, MacGillivray, Ross T.A., Pryzdial, Ed L.G.

    Published in Blood (19-11-2010)
    “…Abstract 1129 Factor × (FX) deficiency is a rare form of haemophilia characterized by a decrease in circulating FX antigen and/or activity levels, which can…”
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    Identification and Cloning of Novel Mutations In a Compound Heterozygous Factor V Deficient Patient by Talbot, Kimberley, Song, Jina, Eghdami, Lily, Tamura-Wells, Jessica, Hewitt, Jeff, Vickars, Linda, Carter, Cedric John, MacGillivray, Ross T.A., Pryzdial, Ed L.G.

    Published in Blood (19-11-2010)
    “…Abstract 2210 Congenital factor V (FV) deficiency is a rare clotting disorder associated with mild to severe hemorrhagic symptoms and a prevalence of…”
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    Novel Compound Heterozygous Factor V Deficiency with Severe Clinical Phenotype by Talbot, Kimberley, Song, Jina, Eghdami, Lily, Hewitt, Jeff, Carter, Cedric J., MacGillivray, Ross T.A., Pryzdial, Ed L.G.

    Published in Blood (20-11-2009)
    “…Abstract 3490 Poster Board III-427 Congenital factor V (FV) deficiency is a rare clotting disorder associated with mild to severe hemorrhagic symptoms and a…”
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    Journal Article
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    Plasmin-Mediated Coagulation Factor Xa Derivative, Xa33/13, Enhances Plasminogen Activation and Fibrin Clot Lysis by Pryzdial, Ed L.G., Talbot, Kimberley, Meixner, Scott C.

    Published in Blood (16-11-2006)
    “…Previous reports showed that coagulation factor Xa (FXa) treated with the fibrinolysis protease, plasmin, loses procoagulant activity and can accelerate tissue…”
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