Search Results - "Pryhuber, Gloria"

Proteomic Analysis of Single Mammalian Cells Enabled by Microfluidic Nanodroplet Sample Preparation and Ultrasensitive NanoLC‐MS by Zhu, Ying, Clair, Geremy, Chrisler, William B., Shen, Yufeng, Zhao, Rui, Shukla, Anil K., Moore, Ronald J., Misra, Ravi S., Pryhuber, Gloria S., Smith, Richard D., Ansong, Charles, Kelly, Ryan T.

“…We report on the quantitative proteomic analysis of single mammalian cells. Fluorescence‐activated cell sorting was employed to deposit cells into a newly…”
Get full text

Renewed Promise of Nonionizing Radiation Imaging for Chronic Lung Disease in Preterm Infants by Pryhuber, Gloria S

“…More than 40% of postnatal deaths are attributable to lung disease, and almost 40% of deaths in preterm infants at least 28 days old are the result of chronic…”
Get full text

Guided construction of single cell reference for human and mouse lung by Guo, Minzhe, Morley, Michael P., Jiang, Cheng, Wu, Yixin, Li, Guangyuan, Du, Yina, Zhao, Shuyang, Wagner, Andrew, Cakar, Adnan Cihan, Kouril, Michal, Jin, Kang, Gaddis, Nathan, Kitzmiller, Joseph A., Stewart, Kathleen, Basil, Maria C., Lin, Susan M., Ying, Yun, Babu, Apoorva, Wikenheiser-Brokamp, Kathryn A., Mun, Kyu Shik, Naren, Anjaparavanda P., Clair, Geremy, Adkins, Joshua N., Pryhuber, Gloria S., Misra, Ravi S., Aronow, Bruce J., Tickle, Timothy L., Salomonis, Nathan, Sun, Xin, Morrisey, Edward E., Whitsett, Jeffrey A., Xu, Yan

“…Accurate cell type identification is a key and rate-limiting step in single-cell data analysis. Single-cell references with comprehensive cell types,…”
Get full text

Type VI collagen promotes lung epithelial cell spreading and wound-closure by Mereness, Jared A, Bhattacharya, Soumyaroop, Wang, Qian, Ren, Yue, Pryhuber, Gloria S, Mariani, Thomas J

“…Basement membrane (BM) is an essential part of the extracellular matrix (ECM) that plays a crucial role in mechanical support and signaling to epithelial cells…”
Get full text

LungMAP: The Molecular Atlas of Lung Development Program by Ardini-Poleske, Maryanne E, Clark, Robert F, Ansong, Charles, Carson, James P, Corley, Richard A, Deutsch, Gail H, Hagood, James S, Kaminski, Naftali, Mariani, Thomas J, Potter, Steven S, Pryhuber, Gloria S, Warburton, David, Whitsett, Jeffrey A, Palmer, Scott M, Ambalavanan, Namasivayam

“…The National Heart, Lung, and Blood Institute is funding an effort to create a molecular atlas of the developing lung (LungMAP) to serve as a research resource…”
Get more information

Lung Gene Expression Analysis (LGEA): an integrative web portal for comprehensive gene expression data analysis in lung development by Du, Yina, Kitzmiller, Joseph A, Sridharan, Anusha, Perl, Anne K, Bridges, James P, Misra, Ravi S, Pryhuber, Gloria S, Mariani, Thomas J, Bhattacharya, Soumyaroop, Guo, Minzhe, Potter, S Steven, Dexheimer, Phillip, Aronow, Bruce, Jobe, Alan H, Whitsett, Jeffrey A, Xu, Yan

“…'LungGENS', our previously developed web tool for mapping single-cell gene expression in the developing lung, has been well received by the pulmonary research…”
Get more information

Preparation of noninfectious scRNAseq samples from SARS-CoV-2-infected epithelial cells by Osborn, Raven M, Leach, Justin, Zanche, Michelle, Ashton, John M, Chu, ChinYi, Thakar, Juilee, Dewhurst, Stephen, Rosenberger, Sonia, Pavelka, Martin, Pryhuber, Gloria S, Mariani, Thomas J, Anderson, Christopher S

“…Coronavirus disease (COVID-19) is an infectious disease caused by the SARS coronavirus 2 (SARS-CoV-2) virus. Direct assessment, detection, and quantitative…”
Get full text

Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs by Syed, Mansoor, Das, Pragnya, Pawar, Aishwarya, Aghai, Zubair H., Kaskinen, Anu, Zhuang, Zhen W., Ambalavanan, Namasivayam, Pryhuber, Gloria, Andersson, Sture, Bhandari, Vineet

“…Hyperoxia-induced acute lung injury (HALI) is a key contributor to the pathogenesis of bronchopulmonary dysplasia (BPD) in neonates, for which no specific…”
Get full text

Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia by Hirani, Dharmesh, Alvira, Cristina M, Danopoulos, Soula, Milla, Carlos, Donato, Michele, Tian, Lu, Mohr, Jasmine, Dinger, Katharina, Vohlen, Christina, Selle, Jaco, V Koningsbruggen-Rietschel, Silke, Barbarino, Verena, Pallasch, Christian, Rose-John, Stefan, Odenthal, Margarete, Pryhuber, Gloria S, Mansouri, Siavash, Savai, Rajkumar, Seeger, Werner, Khatri, Purvesh, Al Alam, Denise, Dötsch, Jörg, Alejandre Alcazar, Miguel A

“…Premature infants exposed to oxygen are at risk for bronchopulmonary dysplasia (BPD), which is characterised by lung growth arrest. Inflammation is important,…”
Get full text

Postnatal Infections and Immunology Affecting Chronic Lung Disease of Prematurity by Pryhuber, Gloria S., MD

“…Premature infants suffer significant respiratory morbidity during infancy with long-term negative consequences on health, quality of life, and health care…”
Get full text

Integration of transcriptomic and proteomic data identifies biological functions in cell populations from human infant lung by Du, Yina, Clair, Geremy C, Al Alam, Denise, Danopoulos, Soula, Schnell, Daniel, Kitzmiller, Joseph A, Misra, Ravi S, Bhattacharya, Soumyaroop, Warburton, David, Mariani, Thomas J, Pryhuber, Gloria S, Whitsett, Jeffrey A, Ansong, Charles, Xu, Yan

“…Systems biology uses computational approaches to integrate diverse data types to understand cell and organ behavior. Data derived from complementary…”
Get more information

Early Neonatal Oxygen Exposure Predicts Pulmonary Morbidity and Functional Deficits at 1 Year by Dylag, Andrew M., Kopin, Hannah G., O'Reilly, Michael A., Wang, Hongyue, Davis, Stephanie D., Ren, Clement L., Pryhuber, Gloria S.

“…To evaluate the predictive value of cumulative oxygen exposure thresholds over the first 2 postnatal weeks, linking them to bronchopulmonary dysplasia (BPD)…”
Get full text

CX3CR1 as a respiratory syncytial virus receptor in pediatric human lung by Anderson, Christopher S., Chu, Chin-Yi, Wang, Qian, Mereness, Jared A., Ren, Yue, Donlon, Kathy, Bhattacharya, Soumyaroop, Misra, Ravi S., Walsh, Edward E., Pryhuber, Gloria S., Mariani, Thomas J.

“…Background Data on the host factors that contribute to infection of young children by respiratory syncytial virus (RSV) are limited. The human chemokine…”
Get full text

Anatomical structures, cell types and biomarkers of the Human Reference Atlas by Börner, Katy, Teichmann, Sarah A., Quardokus, Ellen M., Gee, James C., Browne, Kristen, Osumi-Sutherland, David, Herr, Bruce W., Bueckle, Andreas, Paul, Hrishikesh, Haniffa, Muzlifah, Jardine, Laura, Bernard, Amy, Ding, Song-Lin, Miller, Jeremy A., Lin, Shin, Halushka, Marc K., Boppana, Avinash, Longacre, Teri A., Hickey, John, Lin, Yiing, Valerius, M. Todd, He, Yongqun, Pryhuber, Gloria, Sun, Xin, Jorgensen, Marda, Radtke, Andrea J., Wasserfall, Clive, Ginty, Fiona, Ho, Jonhan, Sunshine, Joel, Beuschel, Rebecca T., Brusko, Maigan, Lee, Sujin, Malhotra, Rajeev, Jain, Sanjay, Weber, Griffin

“…The Human Reference Atlas (HRA) aims to map all of the cells of the human body to advance biomedical research and clinical practice. This Perspective presents…”
Get full text

Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes by Wang, Allen, Chiou, Joshua, Poirion, Olivier B, Buchanan, Justin, Valdez, Michael J, Verheyden, Jamie M, Hou, Xiaomeng, Kudtarkar, Parul, Narendra, Sharvari, Newsome, Jacklyn M, Guo, Minzhe, Faddah, Dina A, Zhang, Kai, Young, Randee E, Barr, Justinn, Sajti, Eniko, Misra, Ravi, Huyck, Heidie, Rogers, Lisa, Poole, Cory, Whitsett, Jeffery A, Pryhuber, Gloria, Xu, Yan, Gaulton, Kyle J, Preissl, Sebastian, Sun, Xin

“…Respiratory failure associated with COVID-19 has placed focus on the lungs. Here, we present single-nucleus accessible chromatin profiles of 90,980 nuclei and…”
Get full text

Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury by Ha, Alison W, Bai, Tao, Ebenezer, David L, Sethi, Tanvi, Sudhadevi, Tara, Mangio, Lizar Ace, Garzon, Steven, Pryhuber, Gloria S, Natarajan, Viswanathan, Harijith, Anantha

“…Neonatal lung injury as a consequence of hyperoxia (HO) therapy and ventilator care contribute to the development of bronchopulmonary dysplasia (BPD)…”
Get more information

Spatial and temporal changes in extracellular elastin and laminin distribution during lung alveolar development by Luo, Yongfeng, Li, Nan, Chen, Hui, Fernandez, G. Esteban, Warburton, David, Moats, Rex, Mecham, Robert P., Krenitsky, Daria, Pryhuber, Gloria S., Shi, Wei

“…Lung alveolarization requires precise coordination of cell growth with extracellular matrix (ECM) synthesis and deposition. The role of extracellular matrices…”
Get full text

Single-cell resolution of human airway epithelial cells exposed to bronchiolitis obliterans-associated chemicals by Chu, Chin-Yi, Kim, So-Young, Pryhuber, Gloria S, Mariani, Thomas J, McGraw, Matthew D

“…Bronchiolitis obliterans (BO) is a fibrotic lung disease characterized by progressive luminal narrowing and obliteration of the small airways. In the…”
Get more information

Pharmacotherapy of acute lung injury and acute respiratory distress syndrome by Raghavendran, Krishnan, Pryhuber, Gloria S, Chess, Patricia R, Davidson, Bruce A, Knight, Paul R, Notter, Robert H

“…Acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) are characterized by rapid-onset respiratory failure following a variety of direct…”
Get more information

Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication by Bozyk, Paul D, Bentley, J Kelley, Popova, Antonia P, Anyanwu, Anuli C, Linn, Marisa D, Goldsmith, Adam M, Pryhuber, Gloria S, Moore, Bethany B, Hershenson, Marc B

“…In bronchopulmonary dysplasia (BPD), alveolar septae are thickened with collagen and α-smooth muscle actin, transforming growth factor (TGF)-β-positive…”
Get full text