Search Results - "Prusty, Archana B."

Histone Methylation by PRC2 Is Inhibited by Active Chromatin Marks by Schmitges, Frank W., Prusty, Archana B., Faty, Mahamadou, Stützer, Alexandra, Lingaraju, Gondichatnahalli M., Aiwazian, Jonathan, Sack, Ragna, Hess, Daniel, Li, Ling, Zhou, Shaolian, Bunker, Richard D., Wirth, Urs, Bouwmeester, Tewis, Bauer, Andreas, Ly-Hartig, Nga, Zhao, Kehao, Chan, Homan, Gu, Justin, Gut, Heinz, Fischle, Wolfgang, Müller, Jürg, Thomä, Nicolas H.

“…The Polycomb repressive complex 2 (PRC2) confers transcriptional repression through histone H3 lysine 27 trimethylation (H3K27me3). Here, we examined how PRC2…”
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A missense mutation in SNRPE linked to non-syndromal microcephaly interferes with U snRNP assembly and pre-mRNA splicing by Chen, Tao, Zhang, Bin, Ziegenhals, Thomas, Prusty, Archana B, Fröhler, Sebastian, Grimm, Clemens, Hu, Yuhui, Schaefke, Bernhard, Fang, Liang, Zhang, Min, Kraemer, Nadine, Kaindl, Angela M, Fischer, Utz, Chen, Wei

“…Malfunction of pre-mRNA processing factors are linked to several human diseases including cancer and neurodegeneration. Here we report the identification of a…”
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Selective inhibition of miRNA processing by a herpesvirus-encoded miRNA by Hennig, Thomas, Prusty, Archana B., Kaufer, Benedikt B., Whisnant, Adam W., Lodha, Manivel, Enders, Antje, Thomas, Julius, Kasimir, Francesca, Grothey, Arnhild, Klein, Teresa, Herb, Stefanie, Jürges, Christopher, Sauer, Markus, Fischer, Utz, Rudel, Thomas, Meister, Gunter, Erhard, Florian, Dölken, Lars, Prusty, Bhupesh K.

“…Herpesviruses have mastered host cell modulation and immune evasion to augment productive infection, life-long latency and reactivation 1 , 2 . A long…”
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TOR signaling regulates liquid phase separation of the SMN complex governing snRNP biogenesis by Schilling, Maximilian, Prusty, Archana B., Boysen, Björn, Oppermann, Felix S., Riedel, Yannick L., Husedzinovic, Alma, Rasouli, Homa, König, Angelika, Ramanathan, Pradhipa, Reymann, Jürgen, Erfle, Holger, Daub, Henrik, Fischer, Utz, Gruss, Oliver J.

“…The activity of the SMN complex in promoting the assembly of pre-mRNA processing UsnRNPs correlates with condensation of the complex in nuclear Cajal bodies…”
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