Search Results - "Pruess, Harald"
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Comparison of Standard Versus Wide-Field Composite Images of the Corneal Subbasal Layer by In Vivo Confocal Microscopy
Published in Investigative ophthalmology & visual science (01-09-2015)“…To evaluate whether the densities of corneal subbasal nerves and epithelial immune dendritiform cells (DCs) are comparable between a set of three…”
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Glutamic acid decarboxylase antibody-associated neurological syndromes: Clinical and antibody characteristics and therapy response
Published in Journal of the neurological sciences (15-02-2023)“…Antibodies against glutamic acid decarboxylase (GAD-abs) at high serum levels are associated with diverse autoimmune neurological syndromes (AINS), including…”
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Autoimmune encephalitis-An update
Published in Nervenarzt (01-06-2023)“…Detection of autoantibodies against neurons and glia cells has brought about the early and specific diagnosis of autoimmune encephalitis in patients with…”
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Autoantibodies in neurological disease
Published in Nature reviews. Immunology (01-12-2021)“…The realization that autoantibodies can contribute to dysfunction of the brain has brought about a paradigm shift in neurological diseases over the past…”
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Postviral autoimmune encephalitis: manifestations in children and adults
Published in Current opinion in neurology (01-06-2017)“…Autoimmune encephalitis is an increasingly recognized neuropsychiatric condition seen in patients of all ages. Herpes virus infections of the brain can…”
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Red Flags: Clinical Signs for Identifying Autoimmune Encephalitis in Psychiatric Patients
Published in Frontiers in psychiatry (16-02-2017)“…Autoimmune mechanisms causing diverse psychiatric symptoms are increasingly recognized and brought about a paradigm shift in neuropsychiatry. Identification of…”
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Molecular disease mechanisms of human antineuronal monoclonal autoantibodies
Published in Trends in molecular medicine (01-01-2023)“…Autoantibodies targeting brain antigens can mediate a wide range of neurological symptoms ranging from epileptic seizures to psychosis to dementia. Although…”
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Evolution from viral encephalitis to autoimmune encephalitis to multiple sclerosis: a case report
Published in Journal of neurology (01-10-2024)“…Background There are established associations between viral and autoimmune encephalitis as well as between autoimmune encephalitis and demyelinating central…”
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Long-term seizure outcome and antiseizure medication use in autoimmune encephalitis
Published in Seizure (London, England) (01-03-2021)“…•Acute-symptomatic seizures are common at onset of autoimmune encephalitis (AE).•In most patients, seizures subside after the acute phase of AE.•Early…”
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Reader Response: Teaching NeuroImage: Atypical Unilateral Cortical Ribboning in Anti-NMDA Receptor Encephalitis
Published in Neurology (02-05-2023)Get full text
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Paraneoplastic Autoimmune Neurological Syndromes and the Role of Immune Checkpoint Inhibitors
Published in Neurotherapeutics (01-04-2022)“…The introduction of immune checkpoint inhibitors (ICIs) in oncologic therapies has led to a paradigm shift in cancer treatment. ICIs have increased the overall…”
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Pathogenic role of autoantibodies against inhibitory synapses
Published in Brain research (15-12-2018)“…•Autoantibodies against inhibitory synapses cause neuropsychiatric diseases.•Human antibodies against GABAergic and glycinergic synapses are directly…”
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Structural mechanisms of GABAA receptor autoimmune encephalitis
Published in Cell (07-07-2022)“…Autoantibodies targeting neuronal membrane proteins can cause encephalitis, seizures, and severe behavioral abnormalities. While antibodies for several…”
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High frequency of cerebrospinal fluid autoantibodies in COVID-19 patients with neurological symptoms
Published in Brain, behavior, and immunity (01-03-2021)“…•COVID-19 patients show a broad spectrum of neurological manifestations.•SARS-CoV-2 is scarcely detected in cerebrospinal fluid.•Viral-triggered autoimmune…”
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Frequencies of neuronal autoantibodies in healthy controls: Estimation of disease specificity
Published in Neurology : neuroimmunology & neuroinflammation (01-09-2017)“…To provide an extensive overview on the prevalence of antibodies against neuronal surfaces (neuronal surface antibody [NSAb]) in healthy participants and…”
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Do cross-reactive antibodies cause neuropathology in COVID-19?
Published in Nature reviews. Immunology (01-11-2020)“…Neurological symptoms are seen in patients with COVID-19 and can persist or re-emerge after clearance of SARS-CoV-2. Recent findings suggest that antibodies to…”
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Autoimmune encephalitis with psychosis: Warning signs, step-by-step diagnostics and treatment
Published in The world journal of biological psychiatry (20-04-2020)“…Objectives: Despite intensive research, schizophrenia and schizoaffective disorders continue to be theoretical constructs that describe clinical syndromes and…”
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Functional connectivity of large-scale brain networks in patients with anti-NMDA receptor encephalitis: an observational study
Published in The Lancet. Psychiatry (01-10-2017)“…In anti-NMDA receptor (NMDAR) encephalitis, antibody-mediated dysfunction of NMDARs causes severe neuropsychiatric symptoms, including psychosis, memory…”
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NMDA receptor autoantibodies primarily impair the extrasynaptic compartment
Published in Brain (London, England : 1878) (01-08-2024)“…Autoantibodies directed against the N-methyl-D-aspartate receptor (NMDAR-Ab) are pathogenic immunoglobulins detected in patients suffering from NMDAR…”
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Antibodies in neurological diseases: Established, emerging, explorative
Published in Immunological reviews (01-10-2024)“…Within a few years, autoantibodies targeting the nervous system resulted in a novel disease classification. For several of them, which we termed 'established',…”
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