Search Results - "Prucker, Isabel"
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The Ip6k1 and Ip6k2 Kinases Are Critical for Normal Renal Tubular Function
Published in Journal of the American Society of Nephrology (01-04-2024)“…Kidneys are gatekeepers of systemic inorganic phosphate balance because they control urinary phosphate excretion. In yeast and plants, inositol…”
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Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase
Published in mBio (14-08-2024)“…Inositol pyrophosphate 1,5-IP regulates expression of a fission yeast phosphate homeostasis regulon, comprising phosphate acquisition genes , , and , via its…”
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Bacterial Pathogen Infection Triggers Magic Spot Nucleotide Signaling in Arabidopsis thaliana Chloroplasts through Specific RelA/SpoT Homologues
Published in Journal of the American Chemical Society (26-07-2023)“…Magic spot nucleotides (p)ppGpp are important signaling molecules in bacteria and plants. In the latter, RelA-SpoT homologue (RSH) enzymes are responsible for…”
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β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner
Published in Proceedings of the National Academy of Sciences - PNAS (22-08-2023)“…Inositol pyrophosphates (PP-InsPs) are energetic signaling molecules with important functions in mammals. As their biosynthesis depends on ATP concentration,…”
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Photoaffinity Capture Compounds to Profile the Magic Spot Nucleotide Interactomes
Published in Angewandte Chemie International Edition (23-05-2022)“…Magic Spot Nucleotides (MSN) regulate the stringent response, a highly conserved bacterial stress adaptation mechanism, enabling survival under adverse…”
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Photoaffinity Capture Compounds to Profile the Magic Spot Nucleotide Interactomes
Published in Angewandte Chemie (23-05-2022)“…Magic Spot Nucleotides (MSN) regulate the stringent response, a highly conserved bacterial stress adaptation mechanism, enabling survival under adverse…”
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Journal Article