Search Results - "Provoost, Sharen"

Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung by De Grove, Katrien C, Provoost, Sharen, Verhamme, Fien M, Bracke, Ken R, Joos, Guy F, Maes, Tania, Brusselle, Guy G

“…Innate lymphoid cells (ILC) are a new family of innate immune cells that have emerged as important regulators of tissue homeostasis and inflammation. However,…”
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The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus –derived serine protease–like protein D by Teufelberger, Andrea R., MSc, Nordengrün, Maria, MSc, Braun, Harald, PhD, Maes, Tania, PhD, De Grove, Katrien, MSc, Holtappels, Gabriele, BSc, O'Brien, Clara, BSc, Provoost, Sharen, PhD, Hammad, Hamida, PhD, Gonçalves, Amanda, MSc, Beyaert, Rudi, PhD, Declercq, Wim, PhD, Vandenabeele, Peter, PhD, Krysko, Dmitri V., PhD, Bröker, Barbara M., PhD, Bachert, Claus, PhD, Krysko, Olga, PhD

“…Background Chronic airway inflammatory diseases, such as chronic rhinosinusitis with nasal polyps and asthma, show increased nasal Staphylococcus aureus…”
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Dermal exposure determines the outcome of repeated airway exposure in a long-term chemical-induced asthma-like mouse model by Pollaris, Lore, Van Den Broucke, Sofie, Decaesteker, Tatjana, Cremer, Jonathan, Seys, Sven, Devos, Fien C., Provoost, Sharen, Maes, Tania, Verbeken, Erik, Vande Velde, Greetje, Nemery, Benoit, Hoet, Peter H.M., Vanoirbeek, Jeroen A.J.

“…Exposure to diisocyanates is an important cause of occupational asthma (OA) in the industrialized world. Since OA occurs after long-term exposure to…”
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Aggravation of Allergic Airway Inflammation by Cigarette Smoke in Mice Is CD44-Dependent by Kumar, Smitha, Lanckacker, Ellen, Dentener, Mieke, Bracke, Ken, Provoost, Sharen, De Grove, Katrien, Brusselle, Guy, Wouters, Emiel, Maes, Tania, Joos, Guy

“…Although epidemiological studies reveal that cigarette smoke (CS) facilitates the development and exacerbation of allergic asthma, these studies offer limited…”
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miR449 Protects Airway Regeneration by Controlling AURKA/HDAC6-Mediated Ciliary Disassembly by Wildung, Merit, Herr, Christian, Riedel, Dietmar, Wiedwald, Cornelia, Moiseenko, Alena, Ramírez, Fidel, Tasena, Hataitip, Heimerl, Maren, Alevra, Mihai, Movsisyan, Naira, Schuldt, Maike, Volceanov-Hahn, Larisa, Provoost, Sharen, Nöthe-Menchen, Tabea, Urrego, Diana, Freytag, Bernard, Wallmeier, Julia, Beisswenger, Christoph, Bals, Robert, van den Berge, Maarten, Timens, Wim, Hiemstra, Pieter S., Brandsma, Corry-Anke, Maes, Tania, Andreas, Stefan, Heijink, Irene H., Pardo, Luis A., Lizé, Muriel

“…Airway mucociliary regeneration and function are key players for airway defense and are impaired in chronic obstructive pulmonary disease (COPD). Using…”
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Mouse models to unravel the role of inhaled pollutants on allergic sensitization and airway inflammation by Maes, Tania, Provoost, Sharen, Lanckacker, Ellen A, Cataldo, Didier D, Vanoirbeek, Jeroen A J, Nemery, Benoit, Tournoy, Kurt G, Joos, Guy F

“…Air pollutant exposure has been linked to a rise in wheezing illnesses. Clinical data highlight that exposure to mainstream tobacco smoke (MS) and…”
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Quantification and role of innate lymphoid cell subsets in Chronic Obstructive Pulmonary Disease by Blomme, Evy E, Provoost, Sharen, De Smet, Elise G, De Grove, Katrien C, Van Eeckhoutte, Hannelore P, De Volder, Joyceline, Hansbro, Philip M, Bonato, Matteo, Saetta, Marina, Wijnant, Sara RA, Verhamme, Fien, Joos, Guy F, Bracke, Ken R, Brusselle, Guy G, Maes, Tania

“…Objectives Innate lymphoid cells (ILCs) secrete cytokines, such as IFN‐γ, IL‐13 and IL‐17, which are linked to chronic obstructive pulmonary disease (COPD)…”
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Inflammasomes in Respiratory Disease by Brusselle, Guy G., MD, PhD, Provoost, Sharen, PhD, Bracke, Ken R., PhD, Kuchmiy, Anna, PhD, Lamkanfi, Mohamed, PhD

“…The respiratory tract of human subjects is constantly exposed to harmful microbes and air pollutants. The immune system responds to these offenders to protect…”
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Role of tumor necrosis factor–α and its receptors in diesel exhaust particle-induced pulmonary inflammation by Kumar, Smitha, Joos, Guy, Boon, Louis, Tournoy, Kurt, Provoost, Sharen, Maes, Tania

“…Inhalation of diesel exhaust particles (DEP) induces an inflammatory reaction in the lung. However, the underlying mechanisms remain to be elucidated. Tumor…”
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Inflammasomes in respiratory disease: from bench to bedside by Brusselle, Guy G, Provoost, Sharen, Bracke, Ken R, Kuchmiy, Anna, Lamkanfi, Mohamed

“…The respiratory tract of human subjects is constantly exposed to harmful microbes and air pollutants. The immune system responds to these offenders to protect…”
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Role of B Cell-Activating Factor in Chronic Obstructive Pulmonary Disease by Seys, Leen J M, Verhamme, Fien M, Schinwald, Anja, Hammad, Hamida, Cunoosamy, Danen Mootoosamy, Bantsimba-Malanda, Claudie, Sabirsh, Alan, McCall, Eileen, Flavell, Liz, Herbst, Ronald, Provoost, Sharen, Lambrecht, Bart N, Joos, Guy F, Brusselle, Guy G, Bracke, Ken R

“…B cell-activating factor (BAFF) plays a major role in activation of B cells and in adaptive humoral immune responses. In chronic obstructive pulmonary disease…”
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Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses by De Grove, Katrien C., Provoost, Sharen, Hendriks, Rudi W., McKenzie, Andrew N.J., Seys, Leen J.M., Kumar, Smitha, Maes, Tania, Brusselle, Guy G., Joos, Guy F.

“…Although the prominent role of TH2 cells in type 2 immune responses is well established, the newly identified type 2 innate lymphoid cells (ILC2s) can also…”
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Monocyte-derived dendritic cell recruitment and allergic T(H)2 responses after exposure to diesel particles are CCR2 dependent by Provoost, Sharen, Maes, Tania, Joos, Guy F, Tournoy, Kurt G

“…The inhalation of diesel exhaust particles (DEPs) is associated with increased sensitization toward inhaled allergens. Dendritic cells (DCs) are important…”
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IL‐33 signalling contributes to pollutant‐induced allergic airway inflammation by De Grove, Katrien C., Provoost, Sharen, Braun, Harald, Blomme, Evy E., Teufelberger, Andrea R., Krysko, Olga, Beyaert, Rudi, Brusselle, Guy G., Joos, Guy F., Maes, Tania

“…Summary Background Clinical and experimental studies have identified a crucial role for IL‐33 and its receptor ST2 in allergic asthma. Inhalation of…”
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Prostaglandin D2 receptor antagonism: a novel therapeutic option for eosinophilic asthma? by Brusselle, Guy G, Provoost, Sharen, Maes, Tania

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Prostaglandin D 2 receptor antagonism: a novel therapeutic option for eosinophilic asthma? by Brusselle, Guy G, Provoost, Sharen, Maes, Tania

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NLRP3/Caspase-1–Independent IL-1β Production Mediates Diesel Exhaust Particle-Induced Pulmonary Inflammation by Provoost, Sharen, Maes, Tania, Pauwels, Nele S., Vanden Berghe, Tom, Vandenabeele, Peter, Lambrecht, Bart N., Joos, Guy F., Tournoy, Kurt G.

“…Abstract Inhalation of diesel exhaust particles (DEP) induces an inflammatory reaction in the lung; however, the mechanisms are largely unclear. IL-1β/IL-1RI…”
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Innate lymphoid cells in isocyanate-induced asthma: role of microRNA-155 by Blomme, Evy E, Provoost, Sharen, Bazzan, Erica, Van Eeckhoutte, Hannelore P, Roffel, Mirjam P, Pollaris, Lore, Bontinck, Annelies, Bonato, Matteo, Vandenbroucke, Louise, Verhamme, Fien, Joos, Guy F, Cosio, Manuel G, Vanoirbeek, Jeroen A J, Brusselle, Guy G, Saetta, Marina, Maes, Tania

“…Occupational asthma, induced by workplace exposures to low molecular weight agents such as toluene 2,4-diisocyanate (TDI), causes a significant burden to…”
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Pro- and Anti-Inflammatory Role of ChemR23 Signaling in Pollutant-Induced Inflammatory Lung Responses by Provoost, Sharen, De Grove, Katrien C, Fraser, Graeme L, Lannoy, Vincent J, Tournoy, Kurt G, Brusselle, Guy G, Maes, Tania, Joos, Guy F

“…Inhalation of traffic-related particulate matter (e.g., diesel exhaust particles [DEPs]) is associated with acute inflammatory responses in the lung, and it…”
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Diesel Exhaust Particles Stimulate Adaptive Immunity by Acting on Pulmonary Dendritic Cells by Provoost, Sharen, Maes, Tania, Willart, Monique A. M, Joos, Guy F, Lambrecht, Bart N, Tournoy, Kurt G

“…Particulate matter, such as diesel exhaust particles (DEPs), modulate adaptive immune responses in the lung; however, their mechanism of action remains largely…”
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