Search Results - "Protti, Giulia"
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Amnion responses to intrauterine inflammation and effects of inhibition of TNF signaling in preterm Rhesus macaque
Published in iScience (17-11-2023)“…Intrauterine infection/inflammation (IUI) is a frequent complication of pregnancy leading to preterm labor and fetal inflammation. How inflammation is…”
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A primer on single-cell RNA-seq analysis using dendritic cells as a case study
Published in FEBS letters (08-09-2024)“…Recent advances in single-cell (sc) transcriptomics have revolutionized our understanding of dendritic cells (DCs), pivotal players of the immune system…”
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CCR4+CD8+ T cells clonally expand to differentiated effectors in murine psoriasis and in human psoriatic arthritis
Published in European journal of immunology (01-04-2023)“…Psoriasis is a chronic inflammatory skin disease with an autoimmune component and associated with joint inflammation in up to 30% of cases. To investigate…”
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Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing
Published in European journal of immunology (01-01-2022)“…Growing evidence suggests that conventional dendritic cells (cDCs) undergo aberrant maturation in COVID‐19, which negatively affects T‐cell activation. The…”
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Abstract LB-B13: Lurbinectedin down-regulates ASCL1 transcription factor in Small Cell Lung Cancer (SCLC)
Published in Molecular cancer therapeutics (01-12-2019)“…Abstract The reported clinical activity of lurbinectedin in Small Cell Lung Cancer (SCLC) prompted us to investigate the selective mechanism of this drug in…”
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iNKT cell-neutrophil crosstalk promotes colorectal cancer pathogenesis
Published in Mucosal immunology (01-06-2023)“…iNKT cells account for a relevant fraction of effector T-cells in the intestine and are considered an attractive platform for cancer immunotherapy. Although…”
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Abstract 3: Multiomics analyses reveal functional DNA, methylation pattern changes in clinical transgenic T-cell receptor cell therapy products
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: Transgenic T-cell receptor T-cells (TCR-T) directed against tumor-specific antigens are associated with robust initial clinical responses…”
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