Search Results - "Protein & cell"

Naringenin reduces lung metastasis in a breast cancer resection model by Qin, Lei, Jin, Lingtao, Lu, Linlin, Lu, Xiaoyan, Zhang, Chunling, Zhang, Fayun, Liang, Wei

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Gadd45a deletion aggravates hematopoietic stem cell dysfunction in ATM-deficient mice by Chen, Yulin, Yang, Runan, Guo, Peng, Ju, Zhenyu

“…Ataxia telangiectasia mutated （ATM） kinase plays an essential role in the maintenance of genomic stability. ATM-deficient （ATM-/-） mice exhibit hematopoietic…”
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Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy by Koppula, Pranavi, Zhuang, Li, Gan, Boyi

“…The cystine/glutamate antiporter SLC7A11 (also commonly known as xCT) functions to import cystine for glutat hione biosynthesis and antioxidant defense and is…”
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A practical guide to amplicon and metagenomic analysis of microbiome data by Liu, Yong-Xin, Qin, Yuan, Chen, Tong, Lu, Meiping, Qian, Xubo, Guo, Xiaoxuan, Bai, Yang

“…Advances in high-throughput sequencing (HTS) have fostered rapid developments in the field of microbiome research, and massive microbiome datasets are now…”
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Metabolic reprogramming and epigenetic modifications on the path to cancer by Sun, Linchong, Zhang, Huafeng, Gao, Ping

“…Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally regulate each other, are among the well-known cancer hallmarks. Recent…”
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Ferroptosis, radiotherapy, and combination therapeutic strategies by Lei, Guang, Mao, Chao, Yan, Yuelong, Zhuang, Li, Gan, Boyi

“…Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages of polyunsaturated-fatty-acid-containing phospholipids in cellular…”
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Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids by Zhao, Bing, Ni, Chao, Gao, Ran, Wang, Yuyan, Yang, Li, Wei, Jinsong, Lv, Ting, Liang, Jianqing, Zhang, Qisheng, Xu, Wei, Xie, Youhua, Wang, Xiaoyue, Yuan, Zhenghong, Liang, Junbo, Zhang, Rong, Lin, Xinhua

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The role of the gut microbiome and its metabolites in metabolic diseases by Wu, Jiayu, Wang, Kai, Wang, Xuemei, Pang, Yanli, Jiang, Changtao

“…It is well known that an unhealthy lifestyle is a major risk factor for metabolic diseases, while in recent years, accumulating evidence has demonstrated that…”
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Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332 by Zhao, Yao, Fang, Chao, Zhang, Qi, Zhang, Ruxue, Zhao, Xiangbo, Duan, Yinkai, Wang, Haofeng, Zhu, Yan, Feng, Lu, Zhao, Jinyi, Shao, Maolin, Yang, Xiuna, Zhang, Leike, Peng, Chao, Yang, Kailin, Ma, Dawei, Rao, Zihe, Yang, Haitao

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Oral microbiomes: more and more importance in oral cavity and whole body by Gao, Lu, Xu, Tiansong, Huang, Gang, Jiang, Song, Gu, Yan, Chen, Feng

“…Microbes appear in every corner of human life, and microbes affect every aspect of human life. The human oral cavity contains a number of different habitats…”
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Antibody-drug conjugates: recent advances in conjugation and linker chemistries by Tsuchikama, Kyoji, An, Zhiqiang

“…The antibody-drug conjugate (ADC), a humanized or human monoclonal antibody conjugated with highly cytotoxic small molecules (payloads) through chemical…”
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Mapping the epigenetic modifications of DNA and RNA by Zhao, Lin-Yong, Song, Jinghui, Liu, Yibin, Song, Chun-Xiao, Yi, Chengqi

“…Over 17 and 160 types of chemical modifications have been identified in DNA and RNA, respectively. The interest in understanding the various biological…”
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Effect of pH, temperature and freezing-thawing on quantity changes and cellular uptake of exosomes by Cheng, Yirui, Zeng, Qingyu, Han, Qing, X ia, Weiliang

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Targeting the alternative bile acid synthetic pathway for metabolic diseases by Jia, Wei, Wei, Meilin, Rajani, Cynthia, Zheng, Xiaojiao

“…The gut microbiota is profoundly involved in glucose and lipid metabolism, in part by regulating bile acid (BA) metabolism and affecting multiple BA-receptor…”
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The microbiome in inflammatory bowel diseases: from pathogenesis to therapy by Liu, Sheng, Zhao, Wenjing, Lan, Ping, Mou, Xiangyu

“…Inflammatory bowel disease (IBD) has become a global disease with accelerating incidence worldwide in the 21st century while its accurate etiology remains…”
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A human circulating immune cell landscape in aging and COVID-19 by Zheng, Yingfeng, Liu, Xiuxing, Le, Wenqing, Xie, Lihui, Li, He, Wen, Wen, Wang, Si, Ma, Shuai, Huang, Zhaohao, Ye, Jinguo, Shi, Wen, Ye, Yanxia, Liu, Zunpeng, Song, Moshi, Zhang, Weiqi, Han, Jing-Dong J., Izpisua Belmonte, Juan Carlos, Xiao, Chuanle, Qu, Jing, Wang, Hongyang, Liu, Guang-Hui, Su, Wenru

“…Age-associated changes in immune cells have been linked to an increased risk for infection. However, a global and detailed characterization of the changes that…”
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Memory T cells: strategies for optimizing tumor immunotherapy by Liu, Qingjun, Sun, Zhongjie, Chen, Ligong

“…Several studies have demonstrated that memory T cells including stem cell memory (Tscm) T cells and central memory (Tcm) T cells show superior persistence and…”
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Gut microbiota derived metabolites in cardiovascular health and disease by Wang, Zeneng, Zhao, Yongzhong

“…Trillions of microbes inhabit the human gut, not only providing nutrients and energy to the host from the ingested food, but also producing metabolic bioactive…”
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Unexpected guests in the tumor microenvironment: microbiome in cancer by Wong-Rolle, Abigail, Wei, Haohan Karen, Zhao, Chen, Jin, Chengcheng

“…Although intestinal microbiome have been established as an important biomarker and regulator of cancer development and therapeutic response, less is known…”
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The hierarchy quorum sensing network in Pseudomonas aeruginosa by Lee, Jasmine, Zhang, Lianhui

“…Pseudomonas aeruginosa causes severe and persistent infections in immune compromised individuals and cystic fibrosis sufferers. The infection is hard to…”
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