Search Results - "Prophete, Colette"
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Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
Published in The Journal of experimental medicine (14-02-2011)“…Hematopoietic stem cells (HSCs) reside in specialized bone marrow (BM) niches regulated by the sympathetic nervous system (SNS). Here, we have examined whether…”
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2
Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice
Published in Blood (04-10-2012)“…Inhibition of leukocyte adhesion to the vascular endothelium represents a novel and important approach for decreasing sickle cell disease (SCD) vaso-occlusion…”
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3
Longitudinal impact on rat cardiac tissue transcriptomic profiles due to acute intratracheal inhalation exposures to isoflurane
Published in PloS one (14-10-2021)“…Isoflurane (ISO) is a widely used inhalation anesthetic in experiments with rodents and humans during surgery. Though ISO has not been reported to impart…”
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Complementary biobank of rodent tissue samples to study the effect of World Trade Center exposure on cancer development
Published in Journal of translational medicine (11-10-2019)“…World Trade Center (WTC) responders were exposed to mixture of dust, smoke, chemicals and carcinogens. New York University (NYU) and Mount Sinai have recreated…”
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Chemical Analysis of World Trade Center Fine Particulate Matter for Use in Toxicologic Assessment
Published in Environmental health perspectives (01-06-2003)“…The catastrophic destruction of the World Trade Center (WTC) on 11 September 2001 caused the release of high levels of airborne pollutants into the local…”
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Comparison of WTC dust size on macrophage inflammatory cytokine release in vivo and in vitro
Published in PloS one (18-07-2012)“…The WTC collapse exposed over 300,000 people to high concentrations of WTC-PM; particulates up to ∼50 mm were recovered from rescue workers' lungs. Elevated…”
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A novel system to generate WTC dust particles for inhalation exposures
Published in Journal of exposure science & environmental epidemiology (01-01-2014)“…First responders (FRs) present at Ground Zero within the critical first 72 h after the World Trade Center (WTC) collapse have progressively exhibited…”
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3189 – ELEVATED CLONAL HEMATOPOIESIS SEEN IN WTC 9/11 FIRST RESPONDERS HAS DISTINCT AGE-RELATED PATTERNS AND RELIES ON IL1RAP FOR CLONAL EXPANSION
Published in Experimental hematology (01-08-2024)“…The terrorist attacks on the World Trade Center (WTC) had an unprecedented environmental impact, exposing people to aerosolized dust and potential carcinogens…”
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Artery-Associated Sympathetic Innervation Drives Rhythmic Vascular Inflammation of Arteries and Veins
Published in Circulation (New York, N.Y.) (24-09-2019)“…BACKGROUND:The incidence of acute cardiovascular complications is highly time-of-day dependent. However, the mechanisms driving rhythmicity of ischemic…”
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Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Published in Molecular cancer research (01-08-2019)“…An excess incidence of prostate cancer has been identified among World Trade Center (WTC) responders. In this study, we hypothesized that WTC dust, which…”
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Impact on rats from acute intratracheal inhalation exposures to WTC dusts
Published in Inhalation toxicology (15-04-2020)“…Background: Studies have revealed the increased incidence of health disorders in First Responders (FR) who were at Ground Zero over the initial 72 hr after the…”
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Longitudinal Impact of WTC Dust Inhalation on Rat Cardiac Tissue Transcriptomic Profiles
Published in International journal of environmental research and public health (14-01-2022)“…First responders (FR) exposed to the World Trade Center (WTC) Ground Zero air over the first week after the 9/11 disaster have an increased heart disease…”
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13
Physiological Contribution of CD44 as a Ligand for E-Selectin during Inflammatory T-Cell Recruitment
Published in The American journal of pathology (01-05-2011)“…Endothelial selectins guide the migration of inflammatory T cells to extralymphoid tissues. Whereas P-selectin glycoprotein ligand-1 (PSGL-1) functions as the…”
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Prostate Cancer in World Trade Center Responders Demonstrate Evidence of an Inflammatory Cascade
Published in Molecular cancer research (20-06-2019)“…An excess incidence of prostate cancer (PCa) has been identified among World Trade Center (WTC) responders. In this study, we hypothesized that WTC dust, which…”
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Impact of acute exposure to WTC dust on ciliated and goblet cells in lungs of rats
Published in Inhalation toxicology (01-01-2015)“…Clinical studies and the World Trade Center (WTC) Health Registry have revealed increases in the incidence of chronic (non-cancer) lung disorders among first…”
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Characterization of the Dust/Smoke Aerosol That Settled East of the World Trade Center (WTC) in Lower Manhattan after the Collapse of the WTC 11 September 2001
Published in Environmental health perspectives (01-07-2002)“…The explosion and collapse of the World Trade Center (WTC) was a catastrophic event that produced an aerosol plume impacting many workers, residents, and…”
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Acute high-level exposure to WTC particles alters expression of genes associated with oxidative stress and immune function in the lung
Published in Journal of immunotoxicology (01-04-2015)“…First responders (FR) present at Ground Zero in the first 72 h after the World Trade Center (WTC) collapsed have progressively exhibited significant…”
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Interactive Effect of Cigarette Smoke Extract and World Trade Center Dust Particles on Airway Cell Cytotoxicity
Published in Journal of Toxicology and Environmental Health, Part A (01-01-2011)“…Rescue workers and residents exposed to the environment surrounding the collapse of the World Trade Center (WTC) on September 11, 2001, have suffered a…”
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Effects of metal compounds with distinct physicochemical properties on iron homeostasis and antibacterial activity in the lungs: chromium and vanadium
Published in Inhalation toxicology (01-02-2010)“…In situ reactions of metal ions or their compounds are important mechanisms by which particles alter lung immune responses. The authors hypothesized that major…”
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Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust
Published in Journal of immunotoxicology (01-12-2010)“…The World Trade Center (WTC) collapse on September 11, 2001 released copious amounts of particulate matter (PM) into the atmosphere of New York City. Follow-up…”
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