Search Results - "Properzi"
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IDPi Catalysis
Published in Angewandte Chemie International Edition (09-09-2019)“…High acidity and structural confinement are pivotal elements in asymmetric acid catalysis. The recently introduced imidodiphosphorimidate (IDPi) Brønsted acids…”
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Sex Differences in the Association of Global Amyloid and Regional Tau Deposition Measured by Positron Emission Tomography in Clinically Normal Older Adults
Published in JAMA neurology (01-05-2019)“…Mounting evidence suggests that sex differences exist in the pathologic trajectory of Alzheimer disease. Previous literature shows elevated levels of…”
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3
Exosomes: the future of biomarkers in medicine
Published in Biomarkers in medicine (01-10-2013)“…Exosomes are nanovesicles secreted into the extracellular environment upon internal vesicle fusion with the plasma membrane. The molecular content of exosomes…”
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Asymmetric Catalysis with CO2: The Direct [alpha]-Allylation of Ketones
Published in Angewandte Chemie International Edition (10-05-2016)“…Quaternary stereocenters are found in numerous bioactive molecules. The Tsuji-Trost reaction has proven to be a powerful C-C bond forming process, and, at…”
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5
Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates
Published in Science (American Association for the Advancement of Science) (12-10-2018)“…Reactions that form a product with the same reactive functionality as that of one of the starting compounds frequently end in oligomerization. As a salient…”
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6
Asymmetric Catalysis with CO2: The Direct α-Allylation of Ketones
Published in Angewandte Chemie International Edition (10-05-2016)“…Quaternary stereocenters are found in numerous bioactive molecules. The Tsuji–Trost reaction has proven to be a powerful C−C bond forming process, and, at…”
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7
Catalytic enantiocontrol over a non-classical carbocation
Published in Nature chemistry (01-12-2020)“…Carbocations can be categorized into classical carbenium ions and non-classical carbonium ions. These intermediates are ubiquitous in reactions of both…”
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Body Model and Biosynthetic Devices: Interpreting Technological Incorporation with the Help of Edmund Husserl's Genetic Phenomenology
Published in Agathos : an international review of the humanities and social sciences (01-01-2022)“…The body model is a relatively new concept, which originates from the science of human embodiment. Cognitive neuroscientists and psychologists that work in…”
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Construction of heterocyclic structures by trivalent cerium salts promoted bond forming reactions
Published in Chemical Society reviews (07-02-2014)“…Cerium(III) salts have recently gained increasing attention in the synthetic community, owing to the powerful features that are reviewed in detail in this…”
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10
Associations between baseline amyloid, sex, and APOE on subsequent tau accumulation in cerebrospinal fluid
Published in Neurobiology of aging (01-06-2019)“…We investigated the effect of baseline Aβ, sex, and APOE on longitudinal tau accumulation in cerebrospinal fluid (CSF) in clinically normal older adults. Two…”
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Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults
Published in NeuroImage (Orlando, Fla.) (15-10-2020)“…Neurofibrillary tau tangles are a hallmark pathology of Alzheimer's disease (AD) and are more closely associated with AD-related cortical atrophy and symptom…”
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Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer's disease
Published in Alzheimer's & dementia (01-03-2019)“…The tau protein plays a central role in Alzheimer's disease (AD), and there is huge interest in measuring tau in blood and cerebrospinal fluid (CSF). We…”
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Extremely Active Organocatalysts Enable a Highly Enantioselective Addition of Allyltrimethylsilane to Aldehydes
Published in Angewandte Chemie International Edition (10-10-2016)“…The enantioselective allylation of aldehydes to form homoallylic alcohols is one of the most frequently used carbon–carbon bond‐forming reaction in chemical…”
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14
Ad Libitum Mediterranean and Low‐Fat Diets Both Significantly Reduce Hepatic Steatosis: A Randomized Controlled Trial
Published in Hepatology (Baltimore, Md.) (01-11-2018)“…Although diet‐induced weight loss is first‐line treatment for patients with nonalcoholic fatty liver disease (NAFLD), long‐term maintenance is difficult. The…”
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15
Region-Specific Association of Subjective Cognitive Decline With Tauopathy Independent of Global β-Amyloid Burden
Published in JAMA neurology (01-12-2017)“…The ability to explore associations between reports of subjective cognitive decline (SCD) and biomarkers of early Alzheimer disease (AD) pathophysiologic…”
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Association of cortical microstructure with amyloid-β and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults
Published in Molecular psychiatry (01-12-2021)“…Noninvasive biomarkers of early neuronal injury may help identify cognitively normal individuals at risk of developing Alzheimer’s disease (AD). A recent…”
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Organocatalytic DYKAT of Si-Stereogenic Silanes
Published in Journal of the American Chemical Society (08-03-2023)“…Chiral organosilanes do not exist in nature and are therefore absent from the “chiral pool”. As a consequence, synthetic approaches toward enantiopure silanes,…”
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18
Corpo vissuto ed esperienza virtuale. Una prospettiva fenomenologica
Published in Rivista internazionale di filosofia e psicologia (01-12-2019)“…In what sense can corporality still be considered a constitutive condition for experience in the current digital age? Recent scholarship in the fields of…”
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The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography
Published in Science translational medicine (20-01-2021)“…Advances in molecular positron emission tomography (PET) have enabled anatomic tracking of brain pathology in longitudinal studies of normal aging and…”
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Sex Mediates Relationships Between Regional Tau Pathology and Cognitive Decline
Published in Annals of neurology (01-11-2020)“…Objective The goal of this study was to examine sex differences in tau distribution across the brain of older adults, using positron emission tomography (PET),…”
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