Search Results - "Proot, Pieter"
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Exploring early combination strategy in Latin American patients with newly diagnosed type 2 diabetes: a sub-analysis of the VERIFY study
Published in Diabetology and metabolic syndrome (15-06-2021)“…Abstract Background Patients with type 2 diabetes mellitus (T2DM) from Latin American countries face challenges in access to healthcare, leading to…”
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Long-Term Glycaemic Durability of Early Combination Therapy Strategy versus Metformin Monotherapy in Korean Patients with Newly Diagnosed Type 2 Diabetes Mellitus
Published in Diabetes & metabolism journal (01-11-2021)“…We assessed the glycaemic durability with early combination (EC; vildagliptin+metformin [MET], n=22) versus MET monotherapy (n=17), among newly-diagnosed type…”
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Glycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial
Published in The Lancet (British edition) (26-10-2019)“…Early treatment intensification leading to sustained good glycaemic control is essential to delay diabetic complications. Although initial combination therapy…”
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Licogliflozin, a Novel SGLT1 and 2 Inhibitor: Body Weight Effects in a Randomized Trial in Adults with Overweight or Obesity
Published in Obesity (Silver Spring, Md.) (01-05-2020)“…Objective The aim of this study was to explore the dose response of licogliflozin, a dual inhibitor of sodium/glucose cotransporter 1 (SGLT1) and 2 (SGLT2), by…”
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Effects of the dual sodium–glucose linked transporter inhibitor, licogliflozin vs placebo or empagliflozin in patients with type 2 diabetes and heart failure
Published in British journal of clinical pharmacology (01-07-2020)“…Aims Explore the efficacy, safety and tolerability of the dual sodium–glucose cotransporter (SGLT) 1 and 2 inhibitor, licogliflozin in patients with type‐2…”
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94-LB: Long-Term Clinical Benefits of Early Combination Approach in Latin American Subpopulation of VERIFY Study
Published in Diabetes (New York, N.Y.) (01-06-2020)“…The VERIFY study showed long-term clinical benefits of the early combination therapy of vildagliptin with metformin (EC) vs. traditional stepwise approach…”
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A pre‐specified statistical analysis plan for the VERIFY study: Vildagliptin efficacy in combination with metformin for early treatment of T2DM
Published in Diabetes, obesity & metabolism (01-10-2019)“…Aims To ensure the integrity of the planned analyses and maximize the clinical utility of the VERIFY study results by describing the detailed concepts behind…”
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FTY720 combined with tacrolimus in de novo renal transplantation: 1-year, multicenter, open-label randomized study
Published in Nephrology, dialysis, transplantation (01-11-2011)“…Background. FTY720 (fingolimod), a novel immunomodulator, has demonstrated potential for prevention of acute rejection in combination with cyclosporine…”
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Pharmacokinetics of Sotrastaurin Combined With Tacrolimus or Mycophenolic Acid in De Novo Kidney Transplant Recipients
Published in Transplantation (15-02-2011)“…Sotrastaurin is a protein kinase C inhibitor in the development for prevention of organ rejection after renal transplantation. In a multicenter phase 2 trial,…”
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Differential cytotoxic effects induced after photosensitization by hypericin
Published in Journal of photochemistry and photobiology. B, Biology (01-04-1997)“…The cytotoxic effects of the natural photosensitizing agent hypericin were evaluated. A dramatic difference in the sensitivity of several different human and…”
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Stability of adenosine in infusion
Published in Journal of pharmaceutical and biomedical analysis (01-07-1998)“…Using liquid chromatography the stability of adenosine in aqueous solution was investigated at five different temperatures, namely 4, 22, 37, 60 and 72°C over…”
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