Search Results - "Pronk, Manon C A"

CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity by Majolée, Jisca, Pronk, Manon C. A., Jim, Kin K., van Bezu, Jan S. M., van der Sar, Astrid M., Hordijk, Peter L., Kovačević, Igor

“…RhoGTPases regulate cytoskeletal dynamics, migration and cell-cell adhesion in endothelial cells. Besides regulation at the level of guanine nucleotide…”
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RhoA, RhoB and RhoC differentially regulate endothelial barrier function by Pronk, Manon C. A., van Bezu, Jan S. M., van Nieuw Amerongen, Geerten P., van Hinsbergh, Victor W. M., Hordijk, Peter L.

“…RhoGTPases are known regulators of intracellular actin dynamics that are important for maintaining endothelial barrier function. RhoA is most extensively…”
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Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity by Botros, Liza, Pronk, Manon C A, Juschten, Jenny, Liddle, John, Morsing, Sofia K H, van Buul, Jaap D, Bates, Robert H, Tuinman, Pieter R, van Bezu, Jan S M, Huveneers, Stephan, Bogaard, Harm Jan, van Hinsbergh, Victor W M, Hordijk, Peter L, Aman, Jurjan

“…Endothelial barrier dysfunction leads to edema and vascular leak, causing high morbidity and mortality. Previously, Abl kinase inhibition has been shown to…”
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FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB by Pronk, Manon C A, Majolée, Jisca, Loregger, Anke, van Bezu, Jan S M, Zelcer, Noam, Hordijk, Peter L, Kovačević, Igor

“…Rho GTPases control both the actin cytoskeleton and adherens junction stability and are recognized as essential regulators of endothelial barrier function…”
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Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity by Botros, Liza, Pronk, Manon C A, Juschten, Jenny, Liddle, John, Morsing, Sofia K S H, van Buul, Jaap D, Bates, Robert H, Tuinman, Pieter R, van Bezu, Jan S M, Huveneers, Stephan, Bogaard, Harm Jan, van Hinsbergh, Victor W M, Hordijk, Peter L, Aman, Jurjan

“…Endothelial barrier dysfunction leads to edema and vascular leak, carrying high morbidity and mortality. Previously, Abl kinase inhibition was shown to protect…”
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