Search Results - "Pronk, Manon C"
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The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB
Published in The Journal of cell biology (05-03-2018)“…RhoGTPases control endothelial cell (EC) migration, adhesion, and barrier formation. Whereas the relevance of RhoA for endothelial barrier function is widely…”
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Journal Article -
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CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity
Published in Scientific reports (31-05-2019)“…RhoGTPases regulate cytoskeletal dynamics, migration and cell-cell adhesion in endothelial cells. Besides regulation at the level of guanine nucleotide…”
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Journal Article -
3
RhoA, RhoB and RhoC differentially regulate endothelial barrier function
Published in Small GTPases (02-11-2019)“…RhoGTPases are known regulators of intracellular actin dynamics that are important for maintaining endothelial barrier function. RhoA is most extensively…”
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4
Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity
Published in Journal of cell science (01-05-2020)“…Endothelial barrier dysfunction leads to edema and vascular leak, causing high morbidity and mortality. Previously, Abl kinase inhibition has been shown to…”
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Journal Article -
5
FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB
Published in Molecular biology of the cell (01-03-2019)“…Rho GTPases control both the actin cytoskeleton and adherens junction stability and are recognized as essential regulators of endothelial barrier function…”
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Journal Article -
6
Bosutinib prevents vascular leakage by reducing focal adhesion turnover and reinforcing junctional integrity
Published in Journal of cell science (01-01-2020)“…Endothelial barrier dysfunction leads to edema and vascular leak, carrying high morbidity and mortality. Previously, Abl kinase inhibition was shown to protect…”
Get full text
Journal Article