Search Results - "Promislow, Daniel E. L"

The Size–Life Span Trade-Off Decomposed: Why Large Dogs Die Young by Kraus, Cornelia, Pavard, Samuel, Promislow, Daniel E. L.

“…Large body size is one of the best predictors of long life span across species of mammals. In marked contrast, there is considerable evidence that, within…”
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The dog aging project: translational geroscience in companion animals by Kaeberlein, Matt, Creevy, Kate E., Promislow, Daniel E. L.

“…Studies of the basic biology of aging have identified several genetic and pharmacological interventions that appear to modulate the rate of aging in laboratory…”
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Dog size and patterns of disease history across the canine age spectrum: Results from the Dog Aging Project by Nam, Yunbi, White, Michelle, Karlsson, Elinor K, Creevy, Kate E, Promislow, Daniel E L, McClelland, Robyn L

“…Age in dogs is associated with the risk of many diseases, and canine size is a major factor in that risk. However, the size patterns are complex. While small…”
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Reproductive capability is associated with lifespan and cause of death in companion dogs by Hoffman, Jessica M, Creevy, Kate E, Promislow, Daniel E L

“…Reproduction is a risky affair; a lifespan cost of maintaining reproductive capability, and of reproduction itself, has been demonstrated in a wide range of…”
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Geographical Distribution and Diversity of Bacteria Associated with Natural Populations of Drosophila melanogaster by Corby-Harris, Vanessa, Pontaroli, Ana Clara, Shimkets, Lawrence J, Bennetzen, Jeffrey L, Habel, Kristin E, Promislow, Daniel E.L

“…Drosophila melanogaster is one of the most widely used model systems in biology. However, little is known about its associated bacterial community. As a first…”
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The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster by Harrison, Benjamin R, Wang, Lu, Gajda, Erika, Hoffman, Elise V, Chung, Brian Y, Pletcher, Scott D, Raftery, Daniel, Promislow, Daniel E L

“…Genetic association studies that seek to explain the inheritance of complex traits typically fail to explain a majority of the heritability of the trait under…”
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PHYLOGENETIC PERSPECTIVES IN THE EVOLUTION OF PARENTAL CARE IN RAY-FINNED FISHES by Mank, Judith E, Promislow, Daniel E. L, Avise, John C

“…Among major vertebrate groups, ray-finned fishes (Actinopterygii) collectively display a nearly unrivaled diversity of parental care activities. This fact,…”
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Metabolic Characterization of the Common Marmoset (Callithrix jacchus) by Go, Young-Mi, Liang, Yongliang, Uppal, Karan, Soltow, Quinlyn A, Promislow, Daniel E L, Wachtman, Lynn M, Jones, Dean P

“…High-resolution metabolomics has created opportunity to integrate nutrition and metabolism into genetic studies to improve understanding of the diverse…”
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Functional and evolutionary inference in gene networks: does topology matter by Siegal, Mark L, Promislow, Daniel E. L, Bergman, Aviv

“…The relationship between the topology of a biological network and its functional or evolutionary properties has attracted much recent interest. It has been…”
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Metabolome-wide association study of phenylalanine in plasma of common marmosets by Go, Young-Mi, Walker, Douglas I., Soltow, Quinlyn A., Uppal, Karan, Wachtman, Lynn M., Strobel, Fredrick H., Pennell, Kurt, Promislow, Daniel E. L., Jones, Dean P.

“…Little systematic knowledge exists concerning the impacts of cumulative lifelong exposure, termed the exposome, on requirements for nutrients. Phenylalanine…”
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Serotonin signaling modulates aging-associated metabolic network integrity in response to nutrient choice in Drosophila melanogaster by Lyu, Yang, Promislow, Daniel E. L., Pletcher, Scott D.

“…Aging arises from complex interactions among multiple biochemical products. Systems-level analyses of biological networks may provide insights into the causes…”
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Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes by Lee, Mitchell B., Dowsett, Ian T., Carr, Daniel T., Wasko, Brian M., Stanton, Sarah G., Chung, Michael S., Ghodsian, Niloufar, Bode, Anna, Kiflezghi, Michael G., Uppal, Priya A., Grayden, Katherine A., Elala, Yordanos C., Tang, Thao T., Tran, Ngoc H. B., Tran, Thu H. B., Diep, Anh B., Hope, Michael, Promislow, Daniel E. L., Kennedy, Scott R., Kaeberlein, Matt, Herr, Alan J.

“…Mutations accumulate within somatic cells and have been proposed to contribute to aging. It is unclear what level of mutation burden may be required to…”
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Evolution of female preference for younger males by Beck, Christopher W, Promislow, Daniel E L

“…Previous theoretical work has suggested that females should prefer to mate with older males, as older males should have higher fitness than the average fitness…”
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Evolution of alternative sex-determining mechanisms in teleost fishes by MANK, JUDITH E., PROMISLOW, DANIEL E. L., AVISE, JOHN C.

“…We compiled information from the literature on the taxonomic distributions in extant teleost fishes of alternative sex‐determination systems:…”
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The companion dog as a model for human aging and mortality by Hoffman, Jessica M., Creevy, Kate E., Franks, Alexander, O'Neill, Dan G., Promislow, Daniel E. L.

“…Summary Around the world, human populations have experienced large increases in average lifespan over the last 150 years, and while individuals are living…”
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All's well that ends well: why large species have short telomeres by Risques, Rosa Ana, Promislow, Daniel E. L.

“…Among mammal species, almost all life-history traits are strongly size dependent. This size dependence even occurs at a molecular level. For example, both…”
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THE ROLE OF PARENTAL AGE EFFECTS ON THE EVOLUTION OF AGING by Priest, Nicholas K, Mackowiak, Benjamin, Promislow, Daniel E. L

“…Many studies have found that older parents have shorter-lived offspring. However, the evolutionary significance of these findings is poorly understood. We…”
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Lifespan of companion dogs seen in three independent primary care veterinary clinics in the United States by Urfer, Silvan R, Kaeberlein, Matt, Promislow, Daniel E L, Creevy, Kate E

“…The privately owned companion dog is an emerging model in comparative medicine, notably because it shares the human environment including its risk factors, is…”
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Correction: Metabolic Characterization of the Common Marmoset (Callithrix jacchus) by Go, Young-Mi, Liang, Yongliang, Uppal, Karan, Soltow, Quinlyn A, Promislow, Daniel E L, Wachtman, Lynn M, Jones, Dean P

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CorDiffViz: an R package for visualizing multi-omics differential correlation networks by Yu, Shiqing, Drton, Mathias, Promislow, Daniel E L, Shojaie, Ali

“…Differential correlation networks are increasingly used to delineate changes in interactions among biomolecules. They characterize differences between omics…”
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