Search Results - "Prokop, J. W."

Beyond thermoregulation: metabolic function of cetacean blubber in migrating bowhead and beluga whales by Ball, H. C., Londraville, R. L., Prokop, J. W., George, John C., Suydam, R. S., Vinyard, C., Thewissen, J. G. M., Duff, R. J.

“…The processes of lipid deposition and utilization, via the gene leptin ( Lep ), are poorly understood in taxa with varying degrees of adipose storage. This…”
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Leptin and leptin receptor: Analysis of a structure to function relationship in interaction and evolution from humans to fish by Prokop, J.W., Duff, R.J., Ball, H.C., Copeland, D.L., Londraville, R.L.

“…Informative docking of Lep and LepR based on sequence alignments and functional data. Amino acids in red are known natural variants associated with disease…”
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Chromosome Y genetic variants: impact in animal models and on human disease by Prokop, J W, Deschepper, C F

“…Chromosome Y (chrY) variation has been associated with many complex diseases ranging from cancer to cardiovascular disorders. Functional roles of chrY genes…”
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Molecular modeling in the age of clinical genomics, the enterprise of the next generation by Prokop, Jeremy W., Lazar, Jozef, Crapitto, Gabrielle, Smith, D. Casey, Worthey, Elizabeth A., Jacob, Howard J.

“…Protein modeling and molecular dynamics hold a unique toolset to aide in the characterization of clinical variants that may result in disease. Not only do…”
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A method for in silico identification of SNAIL/SLUG DNA binding potentials to the E-box sequence using molecular dynamics and evolutionary conserved amino acids by Prokop, Jeremy W., Liu, Yuanjie, Milsted, Amy, Peng, Hongzhuang, Rauscher, Frank J.

“…Binding of transcription factors to DNA is a dynamic process allowing for spatial- and sequence-specificity. Many methods for determination of DNA–protein…”
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