Search Results - "Prokofiev, A B"

Comparative evaluation of recommendations for preclinical studies of transporter-mediated drug–drug interactions by Evteev, V. A., Bunyatyan, N. D., Demchenkova, E. Yu, Prokofiev, A. B.

“…Scientific relevance. Sound recommendations for preclinical studies of transporter- mediated pharmacokinetic interactions of medicinal products can help…”
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Evaluation of Nephrotoxic Properties of Favipiravir Using the RPTEC cell model by Evteev, V. A., Semenova, I. S., Bunyatyan, N. D., Prokofiev, A. B.

“…Scientific relevance. Favipiravir is an antiviral RNA polymerase inhibitor used to treat COVID-19. An adverse drug reaction associated with the use of…”
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Study of Antibacterial Drugs’ Nephrotoxicity in the RPTEC Cell Line by V. A. Evteev, I. S. Semenova, N. D. Bunyatyan, A. B. Prokofiev, V. G. Kukes

“…The created cell line of human proximal renal tubules RPTEC/TERT1 showed maximum compliance with primary human RPTEC, which makes it optimal for use in studies…”
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Susceptibility of HEK293 and RPTEC Cell Lines to Nephrotoxic Effects of Cefuroxime and Cefepime: A Comparative Study by Evteev, V. A., Semenova, I. S., Bunyatyan, N. D., Prokofiev, A. B.

“…Researchers need to identify the nephrotoxic properties of medicinal products both during preclinical development and when exploring options to optimise…”
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Clinical Pharmacology of Antimicrobials: Focus on the Safety of Vancomycin and Linezolid by Zhuravleva, M. V., Kuznetsova, E. V., Berdnikova, N. G., Prokofiev, A. B., Kameneva, T. R., Demchenkova, E. Yu

“…Scientific relevance. Vancomycin and linezolid are the antibacterial agents of choice for severe infections caused by multidrug-resistant pathogens, including…”
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Evaluation of the Effect of Comorbidity on the Efficacy and Safety of β-Lactam Antibiotics in Patients with Community-Acquired Pneumonia by Muslimova, O. V., Sokova, E. A., Prokofiev, A. B., Zhuravleva, M. V., Shapchenko, A. V., Alexandrova, T. V.

“…Lower respiratory tract infections, which include community-acquired pneumonia (CAP), are the most common cause of death among all infectious diseases. The…”
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Retrospective Analysis of the Safety of Antibacterial Medicinal Products for Elderly Patients with Community-Acquired Lower Respiratory Tract Infections by Gorodetskaya, G. I., Prokofiev, A. B., Serebrova, S. Yu, Demchenkova, E. Yu, Zhuravleva, M. V., Demidova, O. A., Alexandrova, T. V., Mazerkina, I. A., Sokova, E. A., Muslimova, O. V.

“…Cephalosporins are the empirical antibiotic therapy (ABT) of choice for patients with community-acquired pneumonia (CAP). When treated with antibiotics,…”
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Experimental Cell Line Models for Nephrotoxicity Screening by Mazerkina, I. A., Evteev, V. A., Prokofiev, A. B., Muslimova, O. V., Demchenkova, E. Yu

“…The aim of the study was to review literature data on cell models for experimental assessment of drug nephrotoxicity in vitro . Because of nephrotoxicity, 2%…”
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Comparative Dissolution Kinetics of Several Multisource Thioctic Acid Products by Vasilenko, G. F., Krasnykh, L. M., Zhuravleva, M. V., Prokofiev, A. B., Gorodetskaya, G. I., Smirnov, V. V., Bunyatyan, N. D.

“…The relationship between dissolution and bioavailability is an example of the interdependency between the quality of a medicinal product and its safety and…”
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Study of Cases of Bacteremia with Gram-Negative Pathogens with Multiple and Extreme Antibiotic Resistance in Real Clinical Practice by M. V. Zhuravleva, B. A. Rodionov, M. A. Lysenko, S. V. Yakovlev, S. S. Andreev, N. N. Ilyukhina, A. B. Prokofiev

“…Aim: To study cases of bacteremia caused by multidrug-resistant (MDR) and extremely-resistant (XDR) gram-negative bacteria in the departments of a…”
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Experience of Using Therapeutic Drug Monitoring to Control the Safety of Vancomycin in Intensive Care Unit Patients with Sepsis by Prokofiev, A. B., Belkov, S. A., Kazakov, R. E., Berdnikova, N. G., Rodina, T. A., Melnikov, E. S., Danko, A. A., Voronova, N. E., Vafina, R. Z., Zavtoniev, A. V., Tsyganko, D. V., Demchenkova, E. Yu

“…Vancomycin is prescribed to patients in serious condition with infections caused by Gram-positive microorganisms; however, if the therapeutic plasma…”
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Nephrotoxicity Biomarkers: Role and Significance in the Diagnosis of Drug-Induced Kidney Injury by Muslimova, O. V., Evteev, V. A., Mazerkina, I. A., Sokova, E. A., Prokofiev, A. B., Shapchenko, A. V., Alexandrova, T. V.

“…Drug-induced kidney injury (DIKI) accounts for 8 to 60% of episodes of acute kidney injury (AKI) among hospital patients. Early DIKI detection and timely…”
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β-Lactam Antibiotics—Drug-Drug Interaction Mediated by Organic Anion Transporters OAT1 and OAT3 by Mazerkina, I. A., Evteev, V. A., Prokofiev, A. B., Muslimova, O. V., Demchenkova, E. Yu

“…Organic anion transporters OAT1 and OAT3 play a key role in elimination of most β-lactam antibiotics. Since nonsteroidal anti-inflammatory drugs, antivirals,…”
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Inhibitors in the Management of Patients with Atherosclerotic Cardiovascular Diseases: Guidelines and Reimbursement Issues by Zhuravleva, M. V., Prokofiev, A. B., Shikh, E. V., Serebrova, S. Yu, Gorodetskaya, G. I., Demchenkova, E. Yu

“…Current guidelines for the management of patients with dyslipidemia define low-density lipoprotein cholesterol (LDL-C) as the primary target in addressing…”
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Carboxytherapy - an innovative trend in resort medicine by Bunyatyan, N D, Drogovoz, S M, Kononenko, A V, Prokofiev, A B

“…Carboxytherapy (the treatment based on carbon dioxide injections) is a multipurpose and widely used medical technology. The use of CO injections…”
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Pharmacogenetic Approaches to Enhancing Efficacy and Safety of Statins as Illustrated by the Example of Atorvastatin by Kazakov, R. Ye, Checha, O. A., Mazerkina, I. A., Demchenkova, E. Yu, Aleksandrova, T. A., Evteev, V. A., Belkov, S. A., Prokofiev, A. B.

“…Statins are efficacious lipid-lowering drugs used for prevention of cardiovascular complications in patients with high blood cholesterol. The efficacy and…”
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The Mechanism of Action of Ethoxidol on Oxidative Stress Indices in Heart Failure and Hypotension by Kukes, V G, Parfenova, O K, Romanov, B K, Prokofiev, A B, Parfenova, E V, Sidorov, N G, Gazdanova, A A, Pavlova, L I, Zozina, V I, Andreev, A D, Aleksandrova, T V, Chernova, S V, Ramenskaya, G V

“…was to study the effect of 2-ethyl-6-methyl-3-hydroxypyridine malate (Ethoxidol) on the concentration of oxidative stress metabolites in patients with chronic…”
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The Mechanism of Action of Follistatin-like Protein-1 (FSTL-1) by Kukes, V. G., Olefir, Yu. V., Romanov, B. K., Prokofiev, A. B., Parfenova, E. V., Boldyreva, M. A., Goroshko, O. A., Parfenova, O. K., Gazdanova, A. A., Demchenkova, E. Yu

“…The paper provides current data on some proteins of the TGF- p family which are potentially capable of exerting a protective effect in diseases of the heart,…”
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Key elements of toxic myocardiopathy pathogenesis by Bunyatyan, N. D., Vlasova, T. I., Myshkina, N. A., Vlasov, A. P., Polozova, E. I., Leshchankina, N. Yu, Prokofiev, A. B., Gurevich, K. G.

“…Goal. To identify key links in the pathogenesis of toxic myocardiopathy in conditions of endogenous intoxication in peritonitis. Materials and methods…”
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PERSONALIZED MEDICINE IN INTERNAL MEDICINE by Kukes, V G, Marinin, V F, Olefir, Yu V, Ramenskaya, G V, Lazareva, N B, Smirnov, V V, Zhuravleva, M V, Prokofiev, A B, Shih, E V, Zhestovskaia, A S, Rumyantsev, N A, Mandich, D V, Goroshko, O A

“…Personalized medicine - a new direction in medicine, which is based on the study of various biomarkers and the use of new methods of molecular analysis…”
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