Search Results - "Proietti Silvestri, Ilaria"

Recent developments in enantio- and diastereoselective hydrogenation of N-heteroaromatic compounds by Gunasekar, Ramachandran, Goodyear, Ross L, Proietti Silvestri, Ilaria, Xiao, Jianliang

“…The enantioselective and diastereoselective hydrogenation of N-heteroaromatic compounds is an efficient strategy to access chirally enriched cyclic…”
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The effect of flavonoids on the reduction of cupric ions, the copper-driven Fenton reaction and copper-triggered haemolysis by Lomozová, Zuzana, Hrubša, Marcel, Conte, Palma Federica, Papastefanaki, Eugenia, Moravcová, Monika, Catapano, Maria Carmen, Proietti Silvestri, Ilaria, Karlíčková, Jana, Kučera, Radim, Macáková, Kateřina, Mladěnka, Přemysl

“…•24 structurally related flavonoids were tested.•Most of them were potent copper reductants.•Eight flavonoids potentiated copper-based Fenton reaction.•Most…”
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Kinetic Resolution of 2‐Aryldihydroquinolines Using Lithiation – Synthesis of Chiral 1,2‐ and 1,4‐Dihydroquinolines by Yeo, Song‐Hee, Choi, Anthony, Greaves, Sophie, Meijer, Anthony J. H. M., Silvestri, Ilaria Proietti, Coldham, Iain

“…Highly enantiomerically enriched dihydrohydroquinolines were prepared in two steps from quinoline. Addition of aryllithiums to quinoline with…”
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Asymmetric Synthesis of 2‐Arylindolines and 2,2‐Disubstituted Indolines by Kinetic Resolution by Choi, Anthony, El‐Tunsi, Ashraf, Wang, Yuhang, Meijer, Anthony J. H. M., Li, Jia, Li, Xiabing, Proietti Silvestri, Ilaria, Coldham, Iain

“…Kinetic resolution of 2‐arylindolines (2,3‐dihydroindoles) was achieved by treatment of their N‐tert‐butoxycarbonyl (Boc) derivatives with n‐butyllithium and…”
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Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N‑Methyl‑d‑aspartate (NMDA) Receptor Antagonist by Gynther, Mikko, Proietti Silvestri, Ilaria, Hansen, Jacob C., Hansen, Kasper B., Malm, Tarja, Ishchenko, Yevheniia, Larsen, Younes, Han, Liwei, Kayser, Silke, Auriola, Seppo, Petsalo, Aleksanteri, Nielsen, Birgitte, Pickering, Darryl S., Bunch, Lennart

“…The most common solid tumors show intrinsic multidrug resistance (MDR) or inevitably acquire such when treated with anticancer drugs. In this work, we describe…”
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Engineered polyester-PEG nanoparticles prepared through a “grafting through” strategy and post-functionalization via Michael type addition by Celentano, Wanda, Battistella, Jonathan, Silvestri, Ilaria Proietti, Bruni, Riccardo, Huang, Xiaoyi, Li, Min, Messa, Piergiorgio, Ordanini, Stefania, Cellesi, Francesco

“…Free radical polymerization (FRP) is widely used in industrial processes as an efficient and versatile method to engineer polymeric nanoparticles (PNPs) of…”
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Iron reduction potentiates hydroxyl radical formation only in flavonols by Macáková, Kateřina, Mladěnka, Přemysl, Filipský, Tomáš, Říha, Michal, Jahodář, Luděk, Trejtnar, František, Bovicelli, Paolo, Proietti Silvestri, Ilaria, Hrdina, Radomír, Saso, Luciano

“…► Flavonoids are potent reductants. ► Iron reduction may intensify Fenton chemistry. ► The majority of flavonoids reduce iron. ► Only a few flavonoids,…”
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Convergent synthesis of mosloflavone, negletein and baicalein from crysin by Righi, Giuliana, Antonioletti, Roberto, Silvestri, Ilaria Proietti, D'Antona, Nicola, Lambusta, Daniela, Bovicelli, Paolo

“…An expeditious synthesis of three polyoxygenated flavones: mosloflavone, negletein and baicalein, starting from crysin, an easily available flavone, by a…”
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Chirality: a key parameter in chemical probes by McGown, Andrew, Nafie, Jordan, Otayfah, Mohammed, Hassell-Hart, Storm, Tizzard, Graham J, Coles, Simon J, Banks, Rebecca, Marsh, Graham P, Maple, Hannah J, Kostakis, George E, Proietti Silvestri, Ilaria, Colbon, Paul, Spencer, John

“…Many small molecule bioactive and marketed drugs are chiral. They are often synthesised from commercially available chiral building blocks. However, chirality…”
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Copper(I)-catalyzed cycloaddition of silver acetylides and azides: incorporation of volatile acetylenes into the triazole core by Proietti Silvestri, Ilaria, Andemarian, Fikre, Khairallah, George N, Yap, Su Wan, Quach, Tim, Tsegay, Sammi, Williams, Craig M, O'Hair, Richard A J, Donnelly, Paul S, Williams, Spencer J

“…Silver acetylides and organic azides react under copper(I) catalysis to afford 1,4-disubstituted 1,2,3-triazoles. Mechanistic studies implicate a process…”
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Protection of cells against oxidative stress by nanomolar levels of hydroxyflavones indicates a new type of intracellular antioxidant mechanism by Lombardo, Emanuele, Sabellico, Cristian, Hájek, Jan, Staňková, Veronika, Filipský, Tomáš, Balducci, Valentina, De Vito, Paolo, Leone, Stefano, Bavavea, Eugenia I, Silvestri, Ilaria Proietti, Righi, Giuliana, Luly, Paolo, Saso, Luciano, Bovicelli, Paolo, Pedersen, Jens Z, Incerpi, Sandra

“…Natural polyphenol compounds are often good antioxidants, but they also cause damage to cells through more or less specific interactions with proteins. To…”
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Simple and efficient synthesis of benzofuran derivatives from tyrosol by Bovicelli, Paolo, Bottaro, Fabrizio, Sappino, Carla, Tomei, Michela, Nardi, Valentina, Proietti Silvestri, Ilaria, Macchi, Beatrice, Frezza, Caterina, Righi, Giuliana

“…A convenient strategy for the preparation of compounds bearing the benzofuran skeleton starting from tyrosol, a phenol largely present in olive oil production…”
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Synthesis and biological evaluation of gallic acid analogs by Barontini, Maurizio, Proietti Silvestri, Ilaria, Nardi, Valentina, Crisante, Fernanda, Pepe, Gaetano, Pari, Luigi, Gallucci, Francesco, Bovicelli, Paolo, Righi, Giuliana

“…A novel and efficient synthesis of pyrogallol moiety through a copper(I)-mediated C–O bond forming reaction is described. In particular, syntheses of…”
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Kinetic Resolution of 2‑Aryl-4-methylenepiperidines toward Enantioenriched Functionalizable Piperidine Fragments by Choi, Anthony, Meijer, Anthony J. H. M., Silvestri, Ilaria Proietti, Coldham, Iain

“…The base n-BuLi with sparteine allows a kinetic resolution of N-Boc-2-aryl-4-methylenepiperidines. The 2,2-disubstituted products and recovered starting…”
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In vitro analysis of iron chelating activity of flavonoids by Mladěnka, Přemysl, Macáková, Kateřina, Filipský, Tomáš, Zatloukalová, Libuše, Jahodář, Luděk, Bovicelli, Paolo, Silvestri, Ilaria Proietti, Hrdina, Radomír, Saso, Luciano

“…Flavonoids have been demonstrated to possess miscellaneous health benefits which are, at least partly, associated with iron chelation. In this in vitro study,…”
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The Growing Importance of Chirality in 3D Chemical Space Exploration and Modern Drug Discovery Approaches for Hit-ID: Topical Innovations by Silvestri, Ilaria Proietti, Colbon, Paul J. J

“…Modern-day drug discovery is now blessed with a wide range of high-throughput hit identification (hit-ID) strategies that have been successfully validated in…”
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AGET ATRP of Poly[poly(ethylene glycol) methyl ether methacrylate] Catalyzed by Hydrophobic Iron(III)-Porphyrins by Proietti Silvestri, I., Cellesi, F.

“…Commercially available hydrophobic porphyrins are investigated as an environmentally friendly catalytic system for iron‐mediated atom transfer radical…”
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Copper and Silver Complexes of Tris(triazole)amine and Tris(benzimidazole)amine Ligands: Evidence that Catalysis of an Azide–Alkyne Cycloaddition (“Click”) Reaction by a Silver Tris(triazole)amine Complex Arises from Copper Impurities by Connell, Timothy U, Schieber, Christine, Silvestri, Ilaria Proietti, White, Jonathan M, Williams, Spencer J, Donnelly, Paul S

“…The synthesis and characterization of a silver complex of the tripodal triazole ligand, tris(benzyltriazolylmethyl)amine (TBTA, L 1 ), that is used as promoter…”
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Augmentation of anti-cancer drug efficacy in murine hepatocellular carcinoma cellsby aperipherally acting competitive N-methyl-D-aspartate (NMDA) receptor antagonist by Gynther, Mikko, Silvestri, Ilaria Proietti, Hansen, Jacob C., Hansen, Kasper B., Malm, Tarja, Ishchenko, Yevheniia, Larsen, Younes, Han, Liwei, Kayser, Silke, Auriola, Seppo, Petsalo, Aleksanteri, Nielsen, Birgitte, Pickering, Darryl S., Bunch, Lennart

“…The most common solid tumors show intrinsic multidrug resistance (MDR) or inevitably acquire suchwhen treated with anticancer drugs. In this work, we describe…”
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Easy Eco-Friendly Phenonium Ion Production from Phenetyl Alcohols in Dimethyl Carbonate by Barontini, Maurizio, Proietti Silvestri, Ilaria, Nardi, V., Bovicelli, Paolo, Pari, L., Gallucci, F., Spezia, Riccardo, Righi, G.

“…An efficient and simple one-pot procedure for selective etherification of 2-aryl-ethylalcohols has been achieved through Amberlyst 15-catalyzed reaction in…”
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