Search Results - "Progress in retinal and eye research"

The progress in understanding and treatment of diabetic retinopathy by Stitt, Alan W., Curtis, Timothy M., Chen, Mei, Medina, Reinhold J., McKay, Gareth J., Jenkins, Alicia, Gardiner, Thomas A., Lyons, Timothy J., Hammes, Hans-Peter, Simó, Rafael, Lois, Noemi

“…Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and remains a leading cause of vision loss globally. Its aetiology and…”
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Immune responses to retinal gene therapy using adeno-associated viral vectors – Implications for treatment success and safety by Bucher, Kirsten, Rodríguez-Bocanegra, Eduardo, Dauletbekov, Daniyar, Fischer, M. Dominik

“…Recombinant adeno-associated virus (AAV) is the leading vector for gene therapy in the retina. As non-pathogenic, non-integrating, replication deficient…”
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Aqueous outflow - A continuum from trabecular meshwork to episcleral veins by Carreon, Teresia, van der Merwe, Elizabeth, Fellman, Ronald L., Johnstone, Murray, Bhattacharya, Sanjoy K.

“…In glaucoma, lowered intraocular pressure (IOP) confers neuroprotection. Elevated IOP characterizes glaucoma and arises from impaired aqueous humor (AH)…”
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Diagnosis and treatment guideline for myopic choroidal neovascularization due to pathologic myopia by Ohno-Matsui, Kyoko, Ikuno, Yasushi, Lai, Timothy Y.Y., Gemmy Cheung, Chui Ming

“…Pathologic myopia is a leading cause of visual impairment. Development of myopic choroidal neovascularization (CNV) is one of the most common complications…”
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Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fish by Lenkowski, Jenny R., Raymond, Pamela A.

“…Adult zebrafish generate new neurons in the brain and retina throughout life. Growth-related neurogenesis allows a vigorous regenerative response to damage,…”
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Innate immune response in retinal homeostasis and inflammatory disorders by Murakami, Yusuke, Ishikawa, Keijiro, Nakao, Shintaro, Sonoda, Koh-Hei

“…Innate immune cells such as neutrophils, monocyte-macrophages and microglial cells are pivotal for the health and disease of the retina. For the maintenance of…”
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X-linked juvenile retinoschisis: Clinical diagnosis, genetic analysis, and molecular mechanisms by Molday, Robert S., Kellner, Ulrich, Weber, Bernhard H.F.

“…X-linked juvenile retinoschisis (XLRS, MIM 312700) is a common early onset macular degeneration in males characterized by mild to severe loss in visual acuity,…”
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Mystery eye: Human adenovirus and the enigma of epidemic keratoconjunctivitis by Jonas, Rahul A., Ung, Lawson, Rajaiya, Jaya, Chodosh, James

“…Known to occur in widespread outbreaks, epidemic keratoconjunctivitis (EKC) is a severe ocular surface infection with a strong historical association with…”
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Polypoidal choroidal vasculopathy and neovascular age-related macular degeneration: Same or different disease? by Laude, Augustinus, Cackett, Peter D., Vithana, Eranga N., Yeo, Ian Y., Wong, Doric, Koh, Adrian H., Wong, Tien Y., Aung, Tin

“…Neovascular age-related macular degeneration (nAMD) is the commonest cause of severe visual impairment in older adults in Caucasian white populations…”
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Optical coherence tomography angiography by Spaide, Richard F., Fujimoto, James G., Waheed, Nadia K., Sadda, Srinivas R., Staurenghi, Giovanni

“…Optical coherence tomography (OCT) was one of the biggest advances in ophthalmic imaging. Building on that platform, OCT angiography (OCTA) provides depth…”
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Digital technology, tele-medicine and artificial intelligence in ophthalmology: A global perspective by Li, Ji-Peng Olivia, Liu, Hanruo, Ting, Darren S.J., Jeon, Sohee, Chan, R.V. Paul, Kim, Judy E., Sim, Dawn A., Thomas, Peter B.M., Lin, Haotian, Chen, Youxin, Sakomoto, Taiji, Loewenstein, Anat, Lam, Dennis S.C., Pasquale, Louis R., Wong, Tien Y., Lam, Linda A., Ting, Daniel S.W.

“…The simultaneous maturation of multiple digital and telecommunications technologies in 2020 has created an unprecedented opportunity for ophthalmology to adapt…”
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Non-syndromic retinitis pigmentosa by Verbakel, Sanne K., van Huet, Ramon A.C., Boon, Camiel J.F., den Hollander, Anneke I., Collin, Rob W.J., Klaver, Caroline C.W., Hoyng, Carel B., Roepman, Ronald, Klevering, B. Jeroen

“…Retinitis pigmentosa (RP) encompasses a group of inherited retinal dystrophies characterized by the primary degeneration of rod and cone photoreceptors. RP is…”
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The epidemics of myopia: Aetiology and prevention by Morgan, Ian G., French, Amanda N., Ashby, Regan S., Guo, Xinxing, Ding, Xiaohu, He, Mingguang, Rose, Kathryn A.

“…There is an epidemic of myopia in East and Southeast Asia, with the prevalence of myopia in young adults around 80–90%, and an accompanying high prevalence of…”
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Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration by Kaarniranta, Kai, Uusitalo, Hannu, Blasiak, Janusz, Felszeghy, Szabolcs, Kannan, Ram, Kauppinen, Anu, Salminen, Antero, Sinha, Debasish, Ferrington, Deborah

“…Oxidative stress-induced damage to the retinal pigment epithelium (RPE) is considered to be a key factor in age-related macular degeneration (AMD) pathology…”
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Inflammation in Glaucoma: From the back to the front of the eye, and beyond by Baudouin, Christophe, Kolko, Miriam, Melik-Parsadaniantz, Stéphane, Messmer, Elisabeth M.

“…The pathophysiology of glaucoma is complex, multifactorial and not completely understood. Elevated intraocular pressure (IOP) and/or impaired retinal blood…”
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Central serous chorioretinopathy: Towards an evidence-based treatment guideline by van Rijssen, Thomas J., van Dijk, Elon H.C., Yzer, Suzanne, Ohno-Matsui, Kyoko, Keunen, Jan E.E., Schlingemann, Reinier O., Sivaprasad, Sobha, Querques, Giuseppe, Downes, Susan M., Fauser, Sascha, Hoyng, Carel B., Piccolino, Felice Cardillo, Chhablani, Jay K., Lai, Timothy Y.Y., Lotery, Andrew J., Larsen, Michael, Holz, Frank G., Freund, K. Bailey, Yannuzzi, Lawrence A., Boon, Camiel J.F.

“…Central serous chorioretinopathy (CSC) is a common cause of central vision loss, primarily affecting men 20–60 years of age. To date, no consensus has been…”
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Deep learning in ophthalmology: The technical and clinical considerations by Ting, Daniel S.W., Peng, Lily, Varadarajan, Avinash V., Keane, Pearse A., Burlina, Philippe M., Chiang, Michael F., Schmetterer, Leopold, Pasquale, Louis R., Bressler, Neil M., Webster, Dale R., Abramoff, Michael, Wong, Tien Y.

“…The advent of computer graphic processing units, improvement in mathematical models and availability of big data has allowed artificial intelligence (AI) using…”
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Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications by Kashani, Amir H., Chen, Chieh-Li, Gahm, Jin K., Zheng, Fang, Richter, Grace M., Rosenfeld, Philip J., Shi, Yonggang, Wang, Ruikang K.

“…OCT has revolutionized the practice of ophthalmology over the past 10–20 years. Advances in OCT technology have allowed for the creation of novel OCT-based…”
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Artificial intelligence in retina by Schmidt-Erfurth, Ursula, Sadeghipour, Amir, Gerendas, Bianca S., Waldstein, Sebastian M., Bogunović, Hrvoje

“…Major advances in diagnostic technologies are offering unprecedented insight into the condition of the retina and beyond ocular disease. Digital images…”
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The cell biology of the retinal pigment epithelium by Lakkaraju, Aparna, Umapathy, Ankita, Tan, Li Xuan, Daniele, Lauren, Philp, Nancy J., Boesze-Battaglia, Kathleen, Williams, David S.

“…The retinal pigment epithelium (RPE), a monolayer of post-mitotic polarized epithelial cells, strategically situated between the photoreceptors and the…”
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