Search Results - "Prodeus, Andrey P"
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Prospective Study of a Cohort of Russian Nijmegen Breakage Syndrome Patients Demonstrating Predictive Value of Low Kappa-Deleting Recombination Excision Circle (KREC) Numbers and Beneficial Effect of Hematopoietic Stem Cell Transplantation (HSCT)
Published in Frontiers in immunology (24-07-2017)“…Nijmegen breakage syndrome (NBS) is a combined primary immunodeficiency with DNA repair defect, microcephaly, and other phenotypical features. It predominantly…”
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A prospective, open-label, non-comparative study of palivizumab prophylaxis in children at high risk of serious respiratory syncytial virus disease in the Russian Federation
Published in BMC research notes (04-09-2012)“…Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections (LRTIs) in children globally. Predisposing conditions for the…”
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Quantitative indicators of TREC and KREC excision circles in malignancies: a prospective cohort study
Published in Sovremennaia onkologiia : zhurnal kafedry onkologii RMAPO dlia nepreryvnogo poslediplomnogo obrazovaniia (03-07-2024)“…Background. In oncology, of particular interest is the study of the T-cell receptor excision circles (TREC) and the κ-deletion B-cell receptor excision circles…”
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Changes in Intestinal Microbiota Composition in 1–5 Years Old Children with Atopic Dermatitis: Cross Sectional Study
Published in Pediatricheskai͡a︡ farmakologii͡a︡ : nauchno-prakticheskiĭ zhurnal Soi͡u︡za pediatrov Rossii (01-12-2021)“…Background . Atopic dermatitis (AD) arouses high research interest these days due to its significant morbidity rate. The most crucial risk factor for its…”
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Immunodeficiency Disorders in Congenital Heart Diseases (Review)
Published in Pediatricheskai͡a︡ farmakologii͡a︡ : nauchno-prakticheskiĭ zhurnal Soi͡u︡za pediatrov Rossii (17-11-2023)“…The study data of the last two decades on primary and secondary immunodeficiency in congenital heart defects (CHD) as a cause of frequent infectious…”
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A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection
Published in The Journal of experimental medicine (21-12-1998)“…To evaluate the role of natural immunoglobulin (Ig)M in the immediate response against microbial infection, we tested mutant mice that are deficient in…”
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A Critical Role for Complement in Maintenance of Self-Tolerance
Published in Immunity (Cambridge, Mass.) (01-11-1998)“…The role of complement in the maintenance of self-tolerance has been examined in two models: an immunoglobulin transgenic model of peripheral tolerance and a…”
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Linkages of innate and adaptive immunity
Published in Current opinion in immunology (01-02-1998)“…The innate immune system is activate by pathogens or environmental antigens following their binding by recognition melocules such as mannan-binding lectin,…”
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Dependence of Germinal Center B Cells on Expression of CD21/CD35 for Survival
Published in Science (American Association for the Advancement of Science) (24-04-1998)“…Affinity-driven selection of B lymphocytes within germinal centers is critical for the development of high-affinity memory cells and host protection. To…”
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Impaired mast cell-dependent natural immunity in complement C3-deficient mice
Published in Nature (London) (01-11-1997)Get full text
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Impaired mast cell-dependent natural immunity in complement C3-deficient mice
Published in Nature (London) (13-11-1997)“…The complement system is widely regarded as essential for normal inflammation, not least because of its ability to activate mast cells. However, recent studies…”
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Endotoxin shock in antibody-deficient mice: unraveling the role of natural antibody and complement in the clearance of lipopolysaccharide
Published in The Journal of immunology (1950) (15-07-1997)“…While the significance of natural Ab is not entirely clear, one proposed role is clearance of bacterial Ags. To determine whether natural Ab was involved in…”
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Increased susceptibility to endotoxin shock in complement C3- and C4- deficient mice is corrected by C1 inhibitor replacement
Published in The Journal of immunology (1950) (15-07-1997)“…Endotoxin shock is a life-threatening syndrome associated with a Gram-negative infection and mediated by a systemic inflammatory response. As a major effector…”
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A small molecular weight factor in aqueous humor acts on C1q to prevent antibody-dependent complement activation
Published in Investigative ophthalmology & visual science (01-05-1998)“…Aqueous humor inhibits activation of the classic complement pathway; however, the mechanism of this inhibition is unknown. We have examined at the molecular…”
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Corneal transplantation in antibody-deficient hosts
Published in Investigative ophthalmology & visual science (01-01-1999)“…To examine the role of donor-specific antibodies, with or without complement, in rejection of orthotopic corneal transplants by using mice as recipients in…”
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Deficiency in complement C4 or receptors CD21/CD35 leads to increased anti-nuclear and -dsDNA antibodies and disease in lpr mice
Published in Molecular immunology (05-04-1998)Get full text
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Role of CD35 in the complement-dependent activation of mast cells
Published in Molecular immunology (05-04-1998)Get full text
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Natural antibody repertoire is dependent on complement receptors CD21/CD35
Published in Molecular immunology (05-04-1998)Get full text
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A critical role of complement in regulation of self-reactive B cells
Published in Molecular immunology (05-04-1998)Get full text
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