Search Results - "Procyshyn, Ric M."
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Long-acting injectable antipsychotics for early psychosis: A comprehensive systematic review
Published in PloS one (29-04-2022)“…Long acting injectable (LAI) antipsychotics are an alternative to oral antipsychotic (OAP) treatment and may be beneficial for patients in the early stages of…”
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A comparison of the metabolic side-effects of the second-generation antipsychotic drugs risperidone and paliperidone in animal models
Published in PloS one (28-01-2021)“…The second generation antipsychotic drugs represent the most common form of pharmacotherapy for schizophrenia disorders. It is now well established that most…”
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Antipsychotic Induced Dopamine Supersensitivity Psychosis: A Comprehensive Review
Published in Current neuropharmacology (01-01-2017)“…Chronic prescription of antipsychotics seems to lose its therapeutic benefits in the prevention of recurring psychotic symptoms. In many instances, the…”
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A Focused Review of the Metabolic Side-Effects of Clozapine
Published in Frontiers in endocrinology (Lausanne) (25-02-2021)“…The second generation antipsychotic drug clozapine represents the most effective pharmacotherapy for treatment-resistant psychosis. It is also associated with…”
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Cardiovascular side-effects of antipsychotic drugs: the role of the autonomic nervous system
Published in Pharmacology & therapeutics (Oxford) (01-08-2012)“…Cardiovascular disease is the leading cause of death in people with severe mental disorders, and rates are proportionally greater than for other diseases such…”
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Associations of substance use, psychosis, and mortality among people living in precarious housing or homelessness: A longitudinal, community-based study in Vancouver, Canada
Published in PLoS medicine (06-07-2020)“…Background The "trimorbidity" of substance use disorder and mental and physical illness is associated with living in precarious housing or homelessness. The…”
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Preclinical models of antipsychotic drug-induced metabolic side effects
Published in Trends in pharmacological sciences (Regular ed.) (01-10-2010)“…Antipsychotic drugs (APDs), and the ‘atypical’ APDs in particular, are commonly associated with metabolic side effects in humans. These include glucose…”
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Clozapine-Induced Cardiovascular Side Effects and Autonomic Dysfunction: A Systematic Review
Published in Frontiers in neuroscience (04-04-2018)“…Clozapine is the antipsychotic of choice for treatment-resistant schizophrenia and has minimal risk for extrapyramidal symptoms. Therapeutic benefits, however,…”
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Antipsychotic prescribing patterns on admission to and at discharge from a tertiary care program for treatment-resistant psychosis
Published in PloS one (10-08-2018)“…Retrospective data were collected from 330 individuals who were treated at a tertiary care program for treatment-resistant psychosis between 1994 and 2010. The…”
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Association between Serum Lipids and Antipsychotic Response in Schizophrenia
Published in Current neuropharmacology (01-01-2019)“…Metabolic abnormalities are serious health problems in individuals with schizophrenia. Paradoxically, studies have noted an association where individuals who…”
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Developing prediction models for symptom severity around the time of discharge from a tertiary-care program for treatment-resistant psychosis
Published in Frontiers in psychiatry (07-06-2023)“…Antipsychotics are the only therapeutic class indicated in the symptomatic management of psychotic disorders. However, individuals diagnosed with schizophrenia…”
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Differential Effects of Acute Treatment With Antipsychotic Drugs on Peripheral Catecholamines
Published in Frontiers in psychiatry (01-12-2020)“…Antipsychotic drugs represent the most effective treatment for chronic psychotic disorders. The newer second generation drugs offer the advantage of fewer…”
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Characterization of mental health in cannabis dispensary users, using structured clinical interviews and standardized assessment instruments
Published in BMC psychiatry (01-11-2019)“…Cannabis is commonly used for its medical properties. In particular, cannabis is purported to have beneficial effects on a wide range of neuropsychiatric…”
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Cognitive profiles and associated structural brain networks in a multimorbid sample of marginalized adults
Published in PloS one (13-06-2019)“…Cognition is impaired in homeless and vulnerably housed persons. Within this heterogeneous and multimorbid group, distinct profiles of cognitive dysfunction…”
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Antipsychotic Drug-Induced Increases in Peripheral Catecholamines are Associated With Glucose Intolerance
Published in Frontiers in pharmacology (15-02-2022)“…The second-generation antipsychotic drugs are widely used in the field of psychiatry, for an expanding number of different conditions. While their clinical…”
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Antipsychotic-Associated Symptoms of Tourette Syndrome: A Systematic Review
Published in CNS drugs (01-10-2018)“…Background Although antipsychotics are used to treat Tourette syndrome, there have been reports of paradoxical induction of tics by first- and…”
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Metabolic side-effects of the novel second-generation antipsychotic drugs asenapine and iloperidone: a comparison with olanzapine
Published in PloS one (09-01-2013)“…The second generation antipsychotic (SGA) drugs are widely used in psychiatry due to their clinical efficacy and low incidence of neurological side-effects…”
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Need for Bioequivalence Standards that Reflect the Clinical Importance of the Complex Pharmacokinetics of Paliperidone Palmitate Long-Acting Injectable Suspension
Published in Journal of pharmacy & pharmaceutical sciences (2019)“…Paliperidone palmitate is a second generation antipsychotic, approved for the treatment of schizophrenia in the form of the long-acting injectable (LAI)…”
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Component Processes of Decision Making in a Community Sample of Precariously Housed Persons: Associations With Learning and Memory, and Health-Risk Behaviors
Published in Frontiers in psychology (02-07-2021)“…The Iowa Gambling Task (IGT) is a widely used measure of decision making, but its value in signifying behaviors associated with adverse, "real-world"…”
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A systematic review of the effects of CYP2D6 phenotypes on risperidone treatment in children and adolescents
Published in Child and adolescent psychiatry and mental health (16-07-2018)“…The second generation antipsychotic drug risperidone is widely used in the field of child and adolescent psychiatry to treat conditions associated with…”
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