Search Results - "Prochazka, Katharina"
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Clinical implications of subclonal TP53 mutations in acute myeloid leukemia
Published in Haematologica (Roma) (01-03-2019)“…The role of subclonal mutations, defined by a variant allele frequency of <20%, has not been addressed in acute myeloid leukemia yet. We, therefore, analyzed…”
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Immune Regulatory Processes of the Tumor Microenvironment under Malignant Conditions
Published in International journal of molecular sciences (10-12-2021)“…The tumor microenvironment (TME) is a critical regulator of tumor growth, progression, and metastasis. Since immune cells represent a large fraction of the…”
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Chronic lymphocytic leukaemia—what is new and notable in 2021, with a special focus on COVID-19
Published in Memo - Magazine of European medical oncology (2021)“…Summary In the last few years, treatment of patients exhibiting chronic lymphocytic leukaemia has changed extensively due to advances in the development of…”
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NCCN-IPI score-independent prognostic potential of pretreatment uric acid levels for clinical outcome of diffuse large B-cell lymphoma patients
Published in British journal of cancer (08-11-2016)“…Background: Blood-based parameters are gaining increasing interest as potential prognostic biomarkers in patients with diffuse large B-cell lymphoma (DLBCL)…”
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Immunohistochemistry for c‐myc and bcl‐2 overexpression improves risk stratification in primary central nervous system lymphoma
Published in Hematological oncology (01-08-2020)“…Overexpression of bcl‐2 and c‐myc are defining features of double‐expressor‐lymphoma (DEL) but may also occur separately in patients with primary central…”
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Distinct Chemokine Receptor Expression Profiles in De Novo DLBCL, Transformed Follicular Lymphoma, Richter's Trans-Formed DLBCL and Germinal Center B-Cells
Published in International journal of molecular sciences (17-07-2022)“…Chemokine receptors and their ligands have been identified as playing an important role in the development of diffuse large B-cell lymphoma (DLBCL), follicular…”
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The CXCR4-CXCL12 -Axis Is of Prognostic Relevance in DLBCL and Its Antagonists Exert Pro-Apoptotic Effects In Vitro
Published in International journal of molecular sciences (24-09-2019)“…In tumor cells of more than 20 different cancer types, the -axis is involved in multiple key processes including proliferation, survival, migration, invasion,…”
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Vinorelbine as substitute for vincristine in patients with diffuse large B cell lymphoma and vincristine-induced neuropathy
Published in Supportive care in cancer (01-09-2021)“…Background A combination of rituximab with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) is the standard first-line therapy for diffuse…”
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A Novel Prognostic Marker for Primary CNS Lymphoma: Lactate Dehydrogenase-to-Lymphocyte Ratio Improves Stratification of Patients Within the Low and Intermediate MSKCC Risk Groups
Published in Frontiers in oncology (03-08-2021)“…Primary central nervous system lymphoma (PCNSL) is a highly aggressive and rare extranodal non-Hodgkin lymphoma (NHL). The MSKCC and the IELSG scores represent…”
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NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes
Published in Cancer research (Chicago, Ill.) (01-05-2017)“…Nuclear orphan receptor NR4A1 exerts an essential tumor suppressor function in aggressive lymphomas. In this study, we investigated the hypothesized…”
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The Role of Immunohistochemical Overexpression of p53 as Adverse Prognostic Factor in Primary Testicular Diffuse Large B Cell Lymphoma
Published in Pathology oncology research (01-10-2020)Get full text
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Impact of the microenvironment on the pathogenesis of mucosa-associated lymphoid tissue lymphomas
Published in World journal of gastrointestinal oncology (15-01-2022)“…Approximately 8% of all non-Hodgkin lymphomas are extranodal marginal zone B cell lymphomas of mucosa-associated lymphoid tissue (MALT), also known as MALT…”
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Prognostic Value of Baseline and Interim Positron Emission Tomography Markers in Diffuse Large B‐cell Lymphoma Patients: A Real‐world Perspective
Published in HemaSphere (01-08-2021)Get full text
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Quantifying the driving factors for language shift in a bilingual region
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2017)“…Many of the world’s around 6,000 languages are in danger of disappearing as people give up use of a minority language in favor of the majority language in a…”
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Best of hematology—2021
Published in Memo - Magazine of European medical oncology (2023)Get full text
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Antibody–drug conjugates in the treatment of lymphoid neoplasms
Published in Memo - Magazine of European medical oncology (01-05-2024)“…Summary Antibody-drug conjugates (ADCs) are a new class of monoclonal antibodies with the characteritic to specifically target tumor cells and to deliver a…”
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Bcl2 inhibitor venetoclax +/− Anti-CD20: what do deep remissions mean?
Published in Memo - Magazine of European medical oncology (01-02-2022)“…Summary In recent years, treatment of patients exhibiting chronic lymphocytic leukemia has changed extensively due to advances in the development of targeted…”
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