Search Results - "Probst, Christine"
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1
Quantum dots as a platform for nanoparticle drug delivery vehicle design
Published in Advanced drug delivery reviews (01-05-2013)“…Nanoparticle-based drug delivery (NDD) has emerged as a promising approach to improving upon the efficacy of existing drugs and enabling the development of new…”
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Journal Article -
2
Rapid Multitarget Immunomagnetic Separation through Programmable DNA Linker Displacement
Published in Journal of the American Chemical Society (02-11-2011)“…Immunomagnetic separation has become an essential tool for high-throughput and low-cost isolation of biomolecules and cells from heterogeneous samples…”
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Journal Article -
3
Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material
Published in Journal of extracellular vesicles (01-01-2019)“…Extracellular vesicles (EVs) mediate targeted cellular interactions in normal and pathophysiological conditions and are increasingly recognised as potential…”
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Journal Article -
4
The in vitro micronucleus assay using imaging flow cytometry and deep learning
Published in NPJ systems biology and applications (18-05-2021)“…The in vitro micronucleus (MN) assay is a well-established assay for quantification of DNA damage, and is required by regulatory bodies worldwide to screen…”
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Journal Article -
5
MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life
Published in Proceedings of the National Academy of Sciences - PNAS (22-08-2017)“…The prenatal period of cortical development is important for the establishment of neural circuitry and functional connectivity of the brain; however, the…”
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Journal Article -
6
Characterization of Protein Aggregates, Silicone Oil Droplets, and Protein-Silicone Interactions Using Imaging Flow Cytometry
Published in Journal of pharmaceutical sciences (01-01-2020)“…Protein therapeutic exposure to siliconized surfaces during manufacturing and storage has potential to induce protein aggregation or generate protein-silicone…”
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Journal Article -
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Characterization of Protein Particles in Therapeutic Formulations Using Imaging Flow Cytometry
Published in Journal of pharmaceutical sciences (01-08-2017)“…Quantitation of particles >10 μm in therapeutic protein formulations is required by pharmacopeia guidelines, and characterization of particles <10 μm is…”
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Journal Article -
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Identifying exosome binding and internalization in blood cell subsets by imaging flow cytometry
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Only recently has the importance of extracellular vesicles as key mediators of intercellular communication been appreciated. Extracellular vesicles…”
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Journal Article -
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Quantitation of sub-visible particles in therapeutic protein formulations using Imaging Flow Cytometry
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Monitoring particles within therapeutic protein formulations is necessary to evaluate drug safety and efficacy. Current regulations require analysis…”
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Journal Article -
10
Silicone oil‐free syringes, siliconized syringes and needles: quantitative assessment of silicone oil release with drugs used for intravitreal injection
Published in Acta ophthalmologica (Oxford, England) (01-12-2021)“…Purpose This study aimed to quantify the amount of silicone oil (SO) released across a variety of syringe and needle models routinely used for intravitreal…”
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Journal Article -
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An Interlaboratory Comparison on the Characterization of a Sub-micrometer Polydisperse Particle Dispersion
Published in Journal of pharmaceutical sciences (01-03-2022)“…The measurement of polydisperse protein aggregates and particles in biotherapeutics remains a challenge, especially for particles with diameters of ≈ 1 µm and…”
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Journal Article -
12
In-vitro assessment of release of silicone oil droplets with the use of variety of syringes and needles used in intravitreal injections
Published in European journal of ophthalmology (01-03-2022)“…Purpose: To assess the variability of silicone oil (SO) particles released across syringes from the same lot and the role of different needle gauges. Materials…”
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Journal Article -
13
Rapid Multi-Target Immuno-Magnetic Separation through Programmable DNA Linker Displacement
Published in Journal of the American Chemical Society (11-10-2011)“…Immuno-magnetic separation has become an essential tool for high throughout and low cost isolation of biomolecules and cells from heterogeneous samples…”
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Journal Article -
14
A Silicone Oil-Free Syringe Tailored for Intravitreal Injection of Biologics
Published in Frontiers in ophthalmology (2022)“…Intravitreal injections (IVI) of biologics targeting vascular endothelial growth factor (anti-VEGF) led to a paradigm shift in the management and prognosis of…”
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Journal Article -
15
Stand-mediated DNA displacement for multiplexed analyte separation and detection
Published 01-01-2012“…Medical and biological research is progressing at an astonishing rate, with an increasing emphasis on the understanding of complex biological systems. At the…”
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Dissertation -
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Reizdarmsyndrom – Colon irritabile
Published in Swiss medical forum (26-09-2012)Get full text
Journal Article -
17
Colon irritable
Published in Forum médical suisse (En ligne) (26-09-2012)Get full text
Journal Article -
18
Technology-Enabled Remote Monitoring and Self-Management - Vision for Patient Empowerment Following Cardiac and Vascular Surgery: User Testing and Randomized Controlled Trial Protocol
Published in JMIR research protocols (01-08-2016)“…Tens of thousands of cardiac and vascular surgeries (CaVS) are performed on seniors in Canada and the United Kingdom each year to improve survival, relieve…”
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Journal Article -
19
Stand-mediated DNA displacement for multiplexed analyte separation and detection
Published in Masters Abstracts International. Vol. 51, no. 03, 58 p. 2012 (01-01-2012)“…Medical and biological research is progressing at an astonishing rate, with an increasing emphasis on the understanding of complex biological systems. At the…”
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Book Chapter -
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Das Europäische Parlament — Bilanz und Perspektiven
Published in Integration (Bonn, Germany) (01-01-1987)Get full text
Journal Article