Search Results - "Probst, Alphonse"

Brain homogenates from human tauopathies induce tau inclusions in mouse brain by Clavaguera, Florence, Akatsu, Hiroyasu, Fraser, Graham, Crowther, R. Anthony, Frank, Stephan, Hench, Jürgen, Probst, Alphonse, Winkler, David T., Reichwald, Julia, Staufenbiel, Matthias, Ghetti, Bernardino, Goedert, Michel, Tolnay, Markus

“…Filamentous inclusions made of hyperphosphorylated tau are characteristic of numerous human neurodegenerative diseases, including Alzheimer’s disease,…”
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Transmission and spreading of tauopathy in transgenic mouse brain by Crowther, R. Anthony, Clavaguera, Florence, Abramowski, Dorothee, Goedert, Michel, Bolmont, Tristan, Probst, Alphonse, Tolnay, Markus, Fraser, Graham, Staufenbiel, Matthias, Stalder, Anna K, Jucker, Mathias, Beibel, Martin, Frank, Stephan

“…Hyperphosphorylated tau makes up the filamentous intracellular inclusions of several neurodegenerative diseases, including Alzheimer's disease. In the disease…”
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Cortical thinning of parahippocampal subregions in very early Alzheimer's disease by Krumm, Sabine, Kivisaari, Sasa L, Probst, Alphonse, Monsch, Andreas U, Reinhardt, Julia, Ulmer, Stephan, Stippich, Christoph, Kressig, Reto W, Taylor, Kirsten I

“…Abstract The stereotypical pattern of neurofibrillary tangle spreading in the earliest stages of typical Alzheimer's dementia (AD) predicts that medial…”
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Anatomic localization of the transentorhinal region of the perirhinal cortex by Taylor, Kirsten I, Probst, Alphonse

“…Abstract Brain imaging measures of entorhinal cortex and hippocampus volumes provide valid and reliable markers of Alzheimer's disease (AD). Since AD…”
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Two Amyloid Precursor Protein Transgenic Mouse Models with Alzheimer Disease-Like Pathology by Sturchler-Pierrat, Christine, Abramowski, Dorothee, Duke, Mairead, Wiederhold, Karl-Heinz, Mistl, Claudia, Rothacher, Sabin, Ledermann, Brigit, Bürki, Kurt, Frey, Peter, Paganetti, Paolo A., Waridel, Caroline, Calhoun, Michael E., Jucker, Mathias, Probst, Alphonse, Staufenbiel, Matthias, Sommer, Bernd

“…Mutations in the amyloid precursor protein (APP) gene cause early-onset familial Alzheimer disease (AD) by affecting the formation of the amyloid β (Aβ )…”
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Delayed Embryonic Lethality in Mice Lacking Protein Phosphatase 2A Catalytic Subunit Cα by Gotz, Jurgen, Probst, Alphonse, Ehler, Elisabeth, Hemmings, Brian, Kues, Wilfried

“…Protein phosphatase 2A (PP2A) is a multimeric enzyme, containing a catalytic subunit complexed with two regulatory subunits. The catalytic subunit PP2A C is…”
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Analysis of gial acidic fibrillary protein in the human entorhinal cortex during aging and in Alzheimer's disease by Porchet, Raymonde, Probst, Alphonse, Bouras, Constantin, Dráberová, Eduarda, Dráber, Pavel, Riederer, Beat M.

“…Glial fibrillary acidic protein, GFAP, is a major intermediate filament protein of glial cells and major cytoskeletal structure in astrocytes. The entorhinal…”
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Intrinsic connectivity of human superior colliculus by Tardif, Eric, Delacuisine, Brigitte, Probst, Alphonse, Clarke, Stephanie

“…The superior colliculus (SC) is believed to play an important role in sensorimotor integration and orienting behavior. It is classically divided into…”
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Ataxin-10, the Spinocerebellar Ataxia Type 10 Neurodegenerative Disorder Protein, Is Essential for Survival of Cerebellar Neurons by März, Pia, Probst, Alphonse, Lang, Sigrid, Schwager, Martine, Rose-John, Stefan, Otten, Uwe, Ozbek, Suat

“…Spinocerebellar ataxia (SCA) type 10, an autosomal dominant disease characterized by cerebellar ataxia, is caused by a novel pentanucleotide (ATTCT) repeat…”
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Oligodendroglial tau filament formation in transgenic mice expressing G272V tau by Götz, Jürgen, Tolnay, Markus, Barmettler, Robi, Chen, Feng, Probst, Alphonse, Nitsch, Roger M.

“…Genetic evidence indicates that several mutations in tau, including G272V, are linked to frontotemporal dementia with parkinsonism. We expressed this mutation…”
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Clinical course of neuropathologically confirmed frontal-variant Alzheimer's disease by Tolnay, Markus, Taylor, Kirsten I, Probst, Alphonse, Miserez, André R, Monsch, Andreas U

“…In this Case Study, a 66-year-old man presented with a clinical syndrome consistent with frontal variant frontotemporal dementia, but neuropathological…”
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Lobar Dementia due to Extreme Widening of Virchow-Robin Spaces in One Hemisphere by Buerge, Christine, Steiger, Gregor, Kneifel, Stefan, Wetzel, Stephan, Wollmer, M.Axel, Probst, Alphonse, Baumann, Thomas P.

“…Widened perivascular spaces known as Virchow-Robin spaces (VRS) are often seen on MRI and are usually incidental findings. It is unclear if enlarged VRS can be…”
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Epilepsia partialis continua: A new manifestation of anti-Hu-associated paraneoplastic encephalomyelitis by Bellaïche Shavit, Yaël, Graus, Francesc, Probst, Alphonse, Rene, Ramon, Steck, Andreas J.

“…We report on 3 anti‐Hu–positive patients who presented with clinical and electroencephalographic (EEG) features of epilepsia partialis continua (EPC). Two of…”
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Tau and neurofilaments in a family with frontotemporal dementia unlinked to chromosome 17q21–22 by Savioz, Armand, Riederer, Beat M, Heutink, Peter, Rizzu, Patrizia, Tolnay, Markus, Kövari, Enikö, Probst, Alphonse, Riederer, I.rène M, Bouras, Constantin, Leuba, Geneviève

“…A Swiss frontotemporal dementia (FTD) kindred with extrapyramidal-like features and without motor neuron disease shows a brain pathology with…”
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Confocal microscopic localization of anti-myelin-associated glycoprotein autoantibodies in a patient with peripheral neuropathy initially lacking a detectable IgM gammopathy by GABRIEL, J.-M, ERNE, B, BERNASCONI, L, TOSI, C, PROBST, A, LANDMANN, L, STECK, A. J

“…We report here on a patient with anti-myelin-associated glycoprotein (MAG) neuropathy in whom examination of a sural nerve biopsy by multichannel confocal…”
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Hippocampal sclerosis dementia: a reappraisal by Probst, Alphonse, Taylor, Kirsten I, Tolnay, Markus

“…Hippocampal sclerosis (HpScl) is characterized by neuronal loss and gliosis in CA1 and subiculum of the hippocampus, and may be one contributing factor to…”
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Argyrophilic grain disease by Tolnay, Markus, Probst, Alphonse

“…This chapter reviews argyrophilic grain disease (AgD), which has emerged as a dementing disorder of old age more frequent than initially thought…”
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Development and Characterization of Antibodies Against the N Terminus of the Human Dopamine D4 Receptor by Lanau, Fabienne, Brockhaus, Manfred, Pink, J. Richard L., Franchet, Christelle, Wildt‐Perinic, Dunja, Goepfert, Corine, Probst, Alphonse, Hartman, Deborah S.

“…: The human dopamine D4 receptor (hD4R), which has been implicated in human diseases such as schizophrenia and in a personality trait called “novelty seeking,”…”
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Subcellular Localization of Wild-Type and Parkinson's Disease-Associated Mutant alpha -Synuclein in Human and Transgenic Mouse Brain by Kahle, Philipp J, Neumann, Manuela, Ozmen, Laurence, Muller, Veronika, Jacobsen, Helmut, Schindzielorz, Alice, Okochi, Masayasu, Leimer, Uwe, van der Putten, Herman, Probst, Alphonse, Kremmer, Elisabeth, Kretzschmar, Hans A, Haass, Christian

“…Mutations in the alpha-synuclein (alphaSYN) gene are associated with rare cases of familial Parkinson's disease, and alphaSYN is a major component of Lewy…”
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Association of Microglia with Amyloid Plaques in Brains of APP23 Transgenic Mice by Stalder, Martina, Phinney, Amie, Probst, Alphonse, Sommer, Bernd, Staufenbiel, Matthias, Jucker, Mathias

“…Microglia are a key component of the inflammatory response in the brain and are associated with senile plaques in Alzheimer's disease (AD). Although there is…”
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