Search Results - "Priyadarshani, Garima"

Oxidative Dearomatization of Indoles via Pd-Catalyzed C–H Oxygenation: An Entry to C2-Quaternary Indolin-3-ones by Guchhait, Sankar K, Chaudhary, Vikas, Rana, Vijay A, Priyadarshani, Garima, Kandekar, Somnath, Kashyap, Maneesh

“…An oxidative dearomatization chemistry of 2-arylindole via a unique pathway involving Pd-catalyzed C–H peroxygenation is documented. Coupled with cascade…”
Get full text

CuSO 4 –Glucose for in Situ Generation of Controlled Cu(I)–Cu(II) Bicatalysts: Multicomponent Reaction of Heterocyclic Azine and Aldehyde with Alkyne, and Cycloisomerization toward Synthesis of N-Fused Imidazoles by Guchhait, Sankar K., Chandgude, Ajay L., Priyadarshani, Garima

Get full text

CuSO4–Glucose for in Situ Generation of Controlled Cu(I)–Cu(II) Bicatalysts: Multicomponent Reaction of Heterocyclic Azine and Aldehyde with Alkyne, and Cycloisomerization toward Synthesis of N-Fused Imidazoles by Guchhait, Sankar K, Chandgude, Ajay L, Priyadarshani, Garima

“…The catalytic efficiency of mixed Cu(I)–Cu(II) system in situ generated by partial reduction of CuSO4 with glucose in ethanol (nonanhydrous) under open air has…”
Get full text

Pd-Catalyzed Ag(I)-Promoted C3-Arylation of Pyrido[1,2‑a]pyrimidin-4-ones with Bromo/Iodo-Arenes by Guchhait, Sankar K, Priyadarshani, Garima

“…A regioselective Ag­(I)-promoted Pd-catalyzed C3–H activation–arylation of pyrido­[1,2-a]­pyrimidin-4-ones with bromo/iodo-(hetero)­arenes under aqueous…”
Get full text

Synthesis of 2‑Arylpyridopyrimidinones, 6‑Aryluracils, and Tri- and Tetrasubstituted Conjugated Alkenes via Pd-Catalyzed Enolic C–O Bond Activation–Arylation by Guchhait, Sankar K, Priyadarshani, Garima

“…A new and efficient approach for the synthesis of biologically important 2-aryl-4H-pyrido­[1,2-a]­pyrimidin-4-ones and 6-aryluracils via previously unknown…”
Get full text

Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of topoisomerase IIα by Priyadarshani, Garima, Amrutkar, Suyog, Nayak, Anmada, Banerjee, Uttam C., Kundu, Chanakya N., Guchhait, Sankar K.

“…A strategy of scaffold-hopping of bioactive natural products, flavones and isoflavones, leading to target-based discovery of potent anticancer agents has been…”
Get full text

Abstract 1713: Novel, potent and orally bioavailable small molecule CD73 inhibitors for cancer immunotherapy by Venkateshappa, Chandregowda, Narayanan, Kishore, Kothandaraman, Prasath, Priyadarshani, Garima, Nair, Rashmi, Goyal, Megha, Ahuja, Vijay Kamal, Dadhania, Sagar, Aravind, AB, Samiulla, DS, Daginakkatte, Girish, Antony, Thomas, Nellore, Kavitha, Panigrahi, Sunil, Chikkanna, Dinesh, Samajdar, Susanta, Ramachandra, Murali

“…CD73 is a cell surface ectoenzyme, which is overexpressed in many types of human and mouse cancers. CD73 is the primary enzymatic producer of immunosuppressive…”
Get full text

Scaffold-Hopping of Aurones: 2‑Arylideneimidazo[1,2‑a]pyridinones as Topoisomerase IIα-Inhibiting Anticancer Agents by Priyadarshani, Garima, Nayak, Anmada, Amrutkar, Suyog M, Das, Sarita, Guchhait, Sankar K, Kundu, Chanakya N, Banerjee, Uttam C

“…Scaffold-hopping of bioactive natural product aurones has been studied for the first time. 2-Arylideneimidazo­[1,2-a]­pyridinones as potential topoisomerase…”
Get full text