Search Results - "Priya, Smriti"

Recent advances in the sustainable design and applications of biodegradable polymers by Rai, Pawankumar, Mehrotra, Srishti, Priya, Smriti, Gnansounou, Edgard, Sharma, Sandeep K.

“…•Plastic recycling models are quantitatively inadequate for sustainability.•Developments in the field of biopolymer degradation to reduce carbon…”
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A natural small molecule‐mediated inhibition of alpha‐synuclein aggregation leads to neuroprotection in Caenorhabditis elegans by Srivastava, Tulika, Tyagi, Divya, Fatima, Siraj, Sathyan, Malur Thirumalesh Vishnu, Raj, Ritu, Sharma, Aniket, Chaturvedi, Minal, Sinha, Meetali, Shishodia, Sonia Kumari, Kumar, Dinesh, Sharma, Sandeep K., Shankar, Jata, Satish, Aruna, Priya, Smriti

“…Small molecules are being explored intensively for their applications as therapeutic molecules in the management of metabolic and neurological disorders. The…”
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Fast kinetics of environmentally induced α-synuclein aggregation mediated by structural alteration in NAC region and result in structure dependent cytotoxicity by Srivastava, Tulika, Raj, Ritu, Dubey, Amit, Kumar, Dinesh, Chaturvedi, Rajnish K., Sharma, Sandeep K., Priya, Smriti

“…Aggregation of α-synuclein (α-syn) is associated with the manifestation of various pathogenic synucleinopathies, including Parkinson’s disease attributed to…”
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Development and Clinical Validation of RT-LAMP-Based Lateral-Flow Devices and Electrochemical Sensor for Detecting Multigene Targets in SARS-CoV-2 by Saxena, Apoorva, Rai, Pawankumar, Mehrotra, Srishti, Baby, Samiya, Singh, Suman, Srivastava, Vikas, Priya, Smriti, Sharma, Sandeep K.

“…Consistently emerging variants and the life-threatening consequences of SARS-CoV-2 have prompted worldwide concern about human health, necessitating rapid and…”
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A polylactic acid-carbon nanofiber-based electro-conductive sensing material and paper-based colorimetric sensor for detection of nitrates by Rai, Pawankumar, Mehrotra, Srishti, Gautam, Krishna, Verma, Rahul, Anbumani, Sadasivam, Patnaik, Satyakam, Priya, Smriti, Sharma, Sandeep K

“…Plastics are ubiquitous in today's lifestyle, and their indiscriminate use has led to the accumulation of plastic waste in landfills and oceans. The waste…”
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Differential interactions of α-synuclein conformers affect refolding and activity of proteins by Bagree, Gayatri, Srivastava, Tulika, Mahasivam, Sanje, Sinha, Meetali, Bansal, Vipul, Ramanathan, Rajesh, Priya, Smriti, Sharma, Sandeep K

“…The accumulation of protein aggregates as intracellular inclusions interferes with cellular protein homeostasis leading to protein aggregation diseases…”
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GroEL and CCT are catalytic unfoldases mediating out-of-cage polypeptide refolding without ATP by Priya, Smriti, Sharma, Sandeep Kumar, Sood, Vishal, Mattoo, Rayees U. H., Finka, Andrija, Azem, Abdussalam, De Los Rios, Paolo, Goloubinoff, Pierre

“…Chaperonins are cage-like complexes in which nonnative polypeptides prone to aggregation are thought to reach their native state optimally. However, they also…”
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Identification of Natural Products as Potential Pharmacological Chaperones for Protein Misfolding Diseases by Sharma, Richa, Srivastava, Tulika, Pandey, Alka Raj, Mishra, Tripti, Gupta, Bhagyashri, Reddy, Sabbu Sathish, Singh, Suriya P., Narender, Tadigoppula, Tripathi, Aradhya, Chandramouli, Balasubramanian, Sashidhara, Koneni V., Priya, Smriti, Kumar, Niti

“…Defective protein folding and accumulation of misfolded proteins is associated with neurodegenerative, cardiovascular, secretory, and metabolic disorders…”
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Engineered Nanoparticle-Protein Interactions Influence Protein Structural Integrity and Biological Significance by Jaiswal, Surabhi, Manhas, Amit, Pandey, Alok Kumar, Priya, Smriti, Sharma, Sandeep K

“…Engineered nanoparticles (ENPs) are artificially synthesized particles with unique physicochemical properties. ENPs are being extensively used in several…”
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A multiplex DNA probe-based method for simultaneous identification of adulteration in meat samples by Singh Yadav, Smriti, Tariq, Ramsha, Kumar Padhy, Prabeen, Saxena, Apoorva, Rai, Pawankumar, Srivastava, Vikas, Kumar, Navjot, Kumar Sharma, Sandeep, Priya, Smriti

“…[Display omitted] •A multiplex TaqMan qRT-PCR method was developed for rapid meat authentication.•Species-specific primers & probes were designed for chicken,…”
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Environmental factors modulating protein conformations and their role in protein aggregation diseases by Devi, Shweta, Chaturvedi, Minal, Fatima, Siraj, Priya, Smriti

“…The adverse physiological conditions have been long known to impact protein synthesis, folding and functionality. Major physiological factors such as the…”
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Mimicking Native Liver Lobule Microarchitecture In Vitro with Parenchymal and Non-parenchymal Cells Using 3D Bioprinting for Drug Toxicity and Drug Screening Applications by Janani, G, Priya, Smriti, Dey, Souradeep, Mandal, Biman B

“…Bioengineering an in vitro liver model recapitulating the native liver microarchitecture consisting of parenchymal and non-parenchymal cells is crucial in…”
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Molecular chaperones as enzymes that catalytically unfold misfolded polypeptides by Priya, Smriti, Sharma, Sandeep K., Goloubinoff, Pierre

“…Stress-denatured or de novo synthesized and translocated unfolded polypeptides can spontaneously reach their native state without assistance of other proteins…”
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Expanding role of molecular chaperones in regulating [alpha]-synuclein misfolding; implications in Parkinson's disease by Sharma, Sandeep K, Priya, Smriti

“…Protein misfolding under stressful environmental conditions cause several cellular problems owing to the disturbed cellular protein homeostasis, which may…”
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Expanding role of molecular chaperones in regulating α-synuclein misfolding; implications in Parkinson’s disease by Sharma, Sandeep K., Priya, Smriti

“…Protein misfolding under stressful environmental conditions cause several cellular problems owing to the disturbed cellular protein homeostasis, which may…”
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Sensor-integrated biocomposite membrane for food quality assessment by Rai, Pawankumar, Verma, Suryansh, Mehrotra, Srishti, Priya, Smriti, Sharma, Sandeep K.

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Pesticide interactions induce alterations in secondary structure of malate dehydrogenase to cause destability and cytotoxicity by Devi, Shweta, Karsauliya, Kajal, Srivastava, Tulika, Raj, Ritu, Kumar, Dinesh, Priya, Smriti

“…Environmental exposure to pesticides increases the risk of neurotoxicity and neurodegenerative diseases. The mechanism of pesticide-induced toxicity is…”
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Advancements in enzyme-based wearable sensors for health monitoring by Mehrotra, Srishti, Rai, Pawankumar, Saxena, Apoorva, Priya, Smriti, Sharma, Sandeep K.

“…[Display omitted] •Wearable sensors gaining popularity owing to their ease-of-use in health monitoring.•Categorization of wearable sensors based on their…”
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Bisphenol-A (BPA) Impairs Hippocampal Neurogenesis via Inhibiting Regulation of the Ubiquitin Proteasomal System by Singh, Sangh Jyoti, Tandon, Ankit, Phoolmala, Srivastava, Tulika, Singh, Nivedita, Goyal, Shweta, Priya, Smriti, Chaturvedi, Rajnish Kumar

“…The ubiquitin–proteasome system (UPS) controls protein homeostasis to maintain cell functionality and survival. Neurogenesis relies on proteasome function, and…”
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Hsp110 Is a Bona Fide Chaperone Using ATP to Unfold Stable Misfolded Polypeptides and Reciprocally Collaborate with Hsp70 to Solubilize Protein Aggregates by Mattoo, Rayees U.H., Sharma, Sandeep K., Priya, Smriti, Finka, Andrija, Goloubinoff, Pierre

“…Structurally and sequence-wise, the Hsp110s belong to a subfamily of the Hsp70 chaperones. Like the classical Hsp70s, members of the Hsp110 subfamily can bind…”
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